TISSUES PROSTATE CANCER CELL LINES AND CANCER TISSUES

was set as 100%. Data are presented asmean ± standard deviation from at leastthree independent experiments.MicroRNA-22 and estrogen receptor a J. Xiong et al.1686 FEBS Journal 277 (2010) 1684–1694 ª 2010 The Authors Journal compilation ª 2010 FEBSABCDGFEFig. 2. Direct regulation of ERa expres[r]

to ensure cell attachment, serial dilutions of the extractsin culture medium were added and incubated for 24 or48 h. Then, cytotoxicity and DNA synthesis rate weredetermined using the MTT assay and tritiated thymidineincorporation, respectively.In testing the cytotoxic or[r]

in our TMA immunoscreen will help us to identify novelJournal of Translational Medicine 2009, 7:8 http://www.translational-medicine.com/content/7/1/8Page 11 of 15(page number not for citation purposes)TRIP-Br2 expression is dysregulated in many human cancer cell linesFigure 4TRIP-Br2 e[r]

expression in all ovarian carcinomas tested, includingundifferentiated subtypes. This could suggest thatHOXA7 is associated with Müllerian differentiation b utis not sufficient to maintain it (Figure 1).Several oth er studies have reported altered HOX geneexpression in ovarian carcinomas when compar[r]

against human antigens used were: mouse monoclonal anti-body against tPA from Abcam (Cambridge, MA, USA);rabbit polyclonal antibody against enolase, mouse mono-clonal antibody against annexin II and rabbit polyclonalantibody against annexin II from Santa Cruz (Santa Cruz,CA, USA); and[r]

lation of CRHSP-28 phosphorylation in cultured muco-sal T84 cells. Am J Physiol Gastrointest Liver Physiol285, G1300–G1309.16 Tiacci E, Orvietani PL, Bigerna B, Pucciarini A, Cor-thals GL, Pettirossi V, Martelli MP, Liso A, BenedettiR, Pacini R et al. (2005) Tumor protein D52 (TPD52):a novel B-ce[r]

[17-19]. Moreover, Moriai et. al reported high levels ofSTYK1 expression even in early stages of breast cancer. Inthis study, we demonstrated the presence of STYK1 immu-noreactivity, in benign and malignant ovarian tissues andcell lines but not in normal ovarian tissue. M[r]

concentration of VD3 exerts its stimulating effects onthe induction of apoptosis in gastric cancer cells, andthis process is tightly associated with the action of epi-genetic modification agents such as TSA ⁄ NaBu and 5-Aza, which either directly, or through transcriptionfactor Egr-1, i[r]

failed to detect the virus in cohorts of prostate cancer patients [5-9]. Very recently, Paprotka et al. (2011) have challenged an association of XMRV with human diseases [10]. These authors have reported that XMRV may have originated by a rare recombination event during tumor passaging[r]

failed to detect the virus in cohorts of prostate cancer patients [5-9]. Very recently, Paprotka et al. (2011) have challenged an association of XMRV with human diseases [10]. These authors have reported that XMRV may have originated by a rare recombination event during tumor passaging[r]

prognosis in comparison with those who had reduced or absent expression levels. Using over-expression andknockdown approach, we created sublines from ESCC cells and further demonstrated that MTSS1 expression inESCC cells significantly influenced the aggressiveness of the oesophageal cancer[r]

prognosis in comparison with those who had reduced or absent expression levels. Using over-expression andknockdown approach, we created sublines from ESCC cells and further demonstrated that MTSS1 expression inESCC cells significantly influenced the aggressiveness of the oesophageal cancer[r]

Figure 4 Characterization of cancer cell killing and loss of client proteins by hybrid Antp-TPR peptide. (A) HEK293T and T47D cellstreated with (+) or without (-) Antp-TPR peptide (68 μM) were analyzed after 24 h by dual-color flow cytometry for annexin V (left and[r]

Department of Pathology, Sapporo Medical University School of Medicine, Sapporo, Japan and 2Department of Urology, Sapporo Medical University School of Medicine, Sapporo, JapanEmail: Ichiya Honma - ichiya@sapmed.ac.jp; Toshihiko Torigoe* - torigoe@sapmed.ac.jp; Yoshihiko Hirohashi - hirohash@[r]

Division of Gynecologic Oncology, Henry Ford Hospital, Detroit, Michigan, USAEmail: Leigh A Solomon - leighsolomon@mac.com; Shadan Ali - alis@karmanos.org; Sanjeev Banerjee - sbanerjee341@hotmail.com; Adnan R Munkarah - amunkar1@hfhs.org; Robert T Morris - morrisr@karmanos.org; Fazlul H Sarkar* - fs[r]

41%, and 38% identity, respectively), the genes of which are also locatedon chromosome 16. Northern hybridization showed that prosemin isexpressed predominantly in the pancreas and weakly in the prostate andcerebellum. However, western blot and RT-PCR analyses showed that[r]

www.genetics.edu.au The Australasian Genetics Resource Book – © 2007 1What is cancer?Each cell contains a copy of the genetic plan for our growth, development and health. This genetic plan comes in the form of the genes, located on chromosomes that we inherit from our parents. T[r]

The PSA era has led to increased diagnosis of early-staged prostate cancer, but stage-forstage cancer-specific mortality has unfortunately remained similar to decades ago.Despite the widespread use of serum PSA, patients with apparently normal PSA valuesmay also have histologica[r]

3In other words, a treatment needs to be potent forits effects to be statistically significant in a smaller sample. Whilethere is not a direct correlation between change in PSA and differ-ences in progression or survival, PSA is used as a primary end pointmeausre of virtually all standard tre[r]

modulated during human melanoma differentiation, growth andprogression. Oncogene 1995, 11:2477-2486.17. Jiang H, Su ZZ, Lin JJ, Goldstein NI, Young CSH, Fisher PB: The melanomadifferentiation associated gene mda-7 suppresses cancer cell growth.Proc Nat Acad Sci USA 1996, 93:9160-9165.1[r]