Classification of biological samples of gene expression data is a basic building block in solving several problems in the field of bioinformatics like cancer and other disease diagnosis and making a proper treatment plan. One big challenge in sample classification is handling large dimensional and r[r]
Triple negative breast cancer (TNBC) is a heterogeneous disease that lacks unifying molecular alterations that can guide therapy decisions. We previously identified distinct molecular subtypes of TNBC (TNBCtype) using gene expression data generated on a microarray platform using frozen tumor specime[r]
II.5. Feature ranking by sensitivity analysis In this Section, we show that ranking features with the magnitude of the weights of a linear discriminant classifier is a principled method. Several authors have suggested to use the change in objective function when one feature is remove[r]
Gene-expression patterns in the cerebellum of iT3 and RTH mice Thyroid hormones are essential for normal brain develop- ment and regulate neuronal proliferation, migration and syn- aptogenesis in the cerebellum [29,30]. In our study, the cerebellum was the least responsive ti[r]
Figures 6a and 6b show the average accuracy and breakeven point ofthe BalancedRandom method compared with the Ratio active method and regular Random method on the Reuters dataset with a [r]
Using knowledge-based interpretation to analyze omics data can not only obtain essential information regarding various biological processes, but also reflect the current physiological status of cells and tissue.
and suggest, as a generalization, that the path from this 40-min oscillation to the cell cycle and circadian rhythms takes place through a series of period two or period three bifurcations. These foldings in the surface of the putative attractor result in an increasingly dense set
Discussion To date, the presence of massive gene expression syn- chronization was shown to be due to presence of meta- bolic cycles [1,3,4]. We show that the most relevant oscillations of transcriptional activities are due to func- tionally aspecific modes, involv[r]
Abstract Recent advances in the study of global patterns of gene expression with the use of microarray technology, coupled with data analysis using sophisticated statistical algorithms, have provided new insights into pathogenic mechanisms of[r]
My project presents the experiment conclusion of the suited of Support vector machines for multi-class text in different datasets and discusses the process of text classification with a [r]
Nowadays, many public repositories containing large microarray gene expression datasets are available. However, the problem lies in the fact that microarray technology are less powerful and accurate than more recent Next Generation Sequencing technologies, such as RNA-Seq.
Microarray experiments comprise more than half of all series in the Gene Expression Omnibus (GEO). However, downloading and analyzing raw or semi-processed microarray data from GEO is not intuitive and requires manual error-prone analysis and a bioinformatics background.
MOLECULAR DATA OF AS II, AS III AND GBM IV We considered raw gene expression and gene copy num-ber data of AS II, AS III, GBM IV and adult normal brain references from epilepsy patients [r]
Microarray data analysis TRANG 4 Results Characterization of the employed breast cancer cell lines First we tested receptor expression of MDA-MB-231 and HS578T cells to characterize the [r]
Dữ liệu biểu hiện của các gen mã hóa NF-YB được tìm hiểu dựa trên dữ liệu microarray trên cổng thông tin Gene Expression Omnibus (GEO)... Tiếp theo, số lượng exon và intron của gen.[r]
SgnesR (Stochastic Gene Network Expression Simulator in R) is an R package that provides an interface to simulate gene expression data from a given gene network using the stochastic simulation algorithm (SSA).
The MLP uses the algorithm of Gradient Back- Propagation for training to update W. B. Structure of MLP Neural Network MLP Neural Network applies for six basic facial expression analysis signed MLP_FEA. MLP_FEA has 6 output nodes corresponding to anger,[r]
Competitive ELISA for CEdG The formation of CEdG modifications of plasmid DNA was monitored by ELISA. Ninety-six-well microtiter plates were coated with 100 l L per well of a carboxy- ethylguanine ⁄ BSA solution (0.2 l gÆmL ) 1 BSA conjugate in 0.2 m sodium carbonate buffer, pH[r]