ASSESSMENT OF PIRNA BIOGENESIS AND FUNCTION IN TESTICULAR GERM CELL TUMORS AND THEIR PRECURSOR GERM CELL NEOPLASIA IN SITU

Tìm thấy 10,000 tài liệu liên quan tới tiêu đề "Assessment of piRNA biogenesis and function in testicular germ cell tumors and their precursor germ...":

ACETYLCHOLINESTERASE OVEREXPRESSION MEDIATED BY ONCOLYTIC ADENOVIRUS EXHIBITED POTENT ANTI-TUMOR EFFECT

ACETYLCHOLINESTERASE OVEREXPRESSION MEDIATED BY ONCOLYTIC ADENOVIRUS EXHIBITED POTENT ANTI-TUMOR EFFECT

We also detected the function of ZD55-AChE in the pancreatic cancer cell line BxPc-3, liver cancer cell line Huh-7 and SMMC-7721, and colon cancer cell line SW480 and HCT116, and found t[r]

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Cell Cycle Regulation in Mammalian Germ Cells

CELL CYCLE REGULATION IN MAMMALIAN GERM CELLS

in the ovary due to the absence of cell death.
6
Cell Cycle Regulation during Prophase I
Prophase I is divided into five stages based upon chromosome appearance (Fig. 1): leptotene (long, thin chromosomes, no pairing), zygotene (homolo- gous pairing and recomb[r]

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Pirfenidone as salvage treatment for refractory bleomycin-induced lung injury: A case report of seminoma

Pirfenidone as salvage treatment for refractory bleomycin-induced lung injury: A case report of seminoma

Bleomycin-induced lung injury, a major complication of chemotherapy for germ cell tumors, occasionally fails to respond to the standard treatment with corticosteroids and develops into severe respiratory insufficiency. Little is known about salvage treatment for refractory cases.

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FELD better not thinking of metastases only when liver lesions appear after bleomycin-based treatment for non-seminoma testis from metastases

FELD better not thinking of metastases only when liver lesions appear after bleomycin-based treatment for non-seminoma testis from metastases

Bleomycin has become an integral part of chemotherapy in patients with germ-cell tumors. One of the most feared side effects is bleomycin-induced pneumonitis. In patients with mild or moderate BIP, radiological signs disappear almost completely within nine months after discontinuation of bleomycin t[r]

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Cancer testis antigens and NY-BR-1 expression in primary breast cancer: Prognostic and therapeutic implications

Cancer testis antigens and NY-BR-1 expression in primary breast cancer: Prognostic and therapeutic implications

Cancer–testis antigens (CTA) comprise a family of proteins, which are physiologically expressed in adult human tissues solely in testicular germ cells and occasionally placenta. However, CTA expression has been reported in various malignancies.

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Analysis of Fertilization pps

ANALYSIS OF FERTILIZATION PPS

SPECIFIC FEATURES OF FERTILIZATION IN ASSISTED REPRODUCTION
Conventional IVF
As compared with natural fertilization, sperm selection is less stringent in in vitro fertilization (IVF) because the fertilizing spermatozoon does not need to penetrate through the cervical mucus and

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Prediction of relapse in stage I testicular germ cell tumor patients on surveillance: Investigation of biomarkers

PREDICTION OF RELAPSE IN STAGE I TESTICULAR GERM CELL TUMOR PATIENTS ON SURVEILLANCE: INVESTIGATION OF BIOMARKERS


testis, but also in a wide range of cancers, with current evidence pointing towards an oncogenic function of these proteins [ 49 ]. Planells-Palop et al. [ 26 ] revealed that TEX19 regulates proliferation and analysis of The Cancer Genome Atlas database sh[r]

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Báo cáo khoa học: The consensus motif for N-myristoylation of plant proteins in a wheat germ cell-free translation system ppt

BÁO CÁO KHOA HỌC: THE CONSENSUS MOTIF FOR N-MYRISTOYLATION OF PLANT PROTEINS IN A WHEAT GERM CELL-FREE TRANSLATION SYSTEM PPT


polymerase (Promega, Madison, WI, USA). In the case of analysis of the sequence specificity of the myristoylation motif, template DNAs for in vitro transcription were pre- pared from the Myr–AGG1-3X6A, Myr–AGG1-3X6S, Myr–AGG1-3X6A7K and Myr–AGG1-3X6S7K vect[r]

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CANONICAL NOTCH SIGNALLING IS INACTIVE IN UROTHELIAL CARCINOMA

CANONICAL NOTCH SIGNALLING IS INACTIVE IN UROTHELIAL CARCINOMA

Notch signalling regulates cell fate in most tissues, promoting precursor cell proliferation in some, but differentiation in others. Accordingly, downregulation or overactivity variously contributes to cancer development. So far, little is known about Notch pathway activity and function in the norma[r]

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Chapter 093. Gynecologic Malignancies (Part 5) ppt

CHAPTER 093 GYNECOLOGIC MALIGNANCIES PART 5 PPT

16% of cases. The gross and microscopic characteristics and the spread of tumor are similar to those of ovarian cancer but can be distinguished if the tumor arises from the endosalpinx, where the tubal epithelium shows a transition between benign <[r]

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POLYSIALIC ACID IS ASSOCIATED WITH BETTER PROGNOSIS AND IDH1-MUTATION IN DIFFUSELY INFILTRATING ASTROCYTOMAS

POLYSIALIC ACID IS ASSOCIATED WITH BETTER PROGNOSIS AND IDH1-MUTATION IN DIFFUSELY INFILTRATING ASTROCYTOMAS

The aim of the study was to assess the localization of Polysialic acid (polySia) and Neural cell adhesion molecule (NCAM) in grade I–IV astrocytomas by confocal microscopy, and also to clarify and compare their relationship to conventional clinicopathological features in these tumors.

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EMBRYONIC STEM CELLS –  BASIC BIOLOGY TO BIOENGINEERING   doc

EMBRYONIC STEM CELLS –  BASIC BIOLOGY TO BIOENGINEERING   DOC

1. Introduction
It is estimated that 2.1 million married couples or 5 million people in the United States are affected by infertility. 1 Infertility is defined as failure to get pregnant after one year of unprotected intercourse. About 40% of infertility cases are due to a[r]

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Generating in vitro solid tumor models on gelatin-alginate scaffolds

Generating in vitro solid tumor models on gelatin-alginate scaffolds

In recent years, three-dimensional (3D) in vitro tumor models have become more common in cancer research across the world. Selecting scaffolds, seeding cells into the scaffolds, and culturing them are pivotal for the morphologies and proliferation of cancer cell lines. Therefore, this experience has[r]

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TYROSINE PHOSPHORYLATION PROFILING VIA IN SITU PROXIMITY LIGATION ASSAY

TYROSINE PHOSPHORYLATION PROFILING VIA IN SITU PROXIMITY LIGATION ASSAY

Tyrosine phosphorylation (pTyr) is an important cancer relevant posttranslational modification since it regulates protein activity and cellular localization. By controlling cell growth and differentiation it plays an important role in tumor development. This paper describes a novel approach for dete[r]

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INACTIVATION OF THE TUMOR SUPPRESSOR GENE VON HIPPEL-LINDAU (VHL) IN GRANULOCYTES CONTRIBUTES TO DEVELOPMENT OF LIVER HEMANGIOMAS IN A MOUSE MODEL

INACTIVATION OF THE TUMOR SUPPRESSOR GENE VON HIPPEL-LINDAU (VHL) IN GRANULOCYTES CONTRIBUTES TO DEVELOPMENT OF LIVER HEMANGIOMAS IN A MOUSE MODEL

Mutations in the tumor suppressor gene von Hippel-Lindau (VHL) underlie a hereditary cancer syndrome—VHL disease—and are also frequently observed in sporadic renal cell carcinoma of the clear cell type (ccRCC). VHL disease is characterized by malignant and benign tumors in a few specific tissues, in[r]

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CHAPTER 23 – ROLE OF ABCA1 IN CELL TURNOVER AND LIPID HOMEOSTASIS

CHAPTER 23 – ROLE OF ABCA1 IN CELL TURNOVER AND LIPID HOMEOSTASIS

CHAPTER 23 – ROLE OF ABCA1 IN CELL TURNOVER AND LIPID HOMEOSTASIS CHAPTER 23 – ROLE OF ABCA1 IN CELL TURNOVER AND LIPID HOMEOSTASIS CHAPTER 23 – ROLE OF ABCA1 IN CELL TURNOVER AND LIPID HOMEOSTASIS CHAPTER 23 – ROLE OF ABCA1 IN CELL TURNOVER AND LIPID HOMEOSTASIS CHAPTER 23 – ROLE OF ABCA1 IN CELL T[r]

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Clinical significance of OCT4 and SOX2 protein expression in cervical cancer

Clinical significance of OCT4 and SOX2 protein expression in cervical cancer

Cancer stem cell markers have become a major research focus because of their relationship with radiation or chemotherapy resistance in cancer therapy. Cancer stem cell markers including OCT4 and SOX2 have been found in various solid tumors. Here, we investigate the expression and clinical significan[r]

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RECAPITULATING EPITHELIAL TUMOR MICROENVIRONMENT IN VITRO USING THREE DIMENSIONAL TRI-CULTURE OF HUMAN EPITHELIAL, ENDOTHELIAL, AND MESENCHYMAL CELLS

RECAPITULATING EPITHELIAL TUMOR MICROENVIRONMENT IN VITRO USING THREE DIMENSIONAL TRI-CULTURE OF HUMAN EPITHELIAL, ENDOTHELIAL, AND MESENCHYMAL CELLS

Results and discussion Characterization of STEMs Since epithelial tumors are heterogeneous with respect to their cell population and also comprise mesenchymal cells, endothelial cell, im[r]

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Chapter 105. Malignancies of Lymphoid Cells (Part 11) pot

CHAPTER 105 MALIGNANCIES OF LYMPHOID CELLS PART 11 POT

Precursor B cell lymphoblastic lymphoma is a rare presentation of precursor B cell lymphoblastic malignancy. These patients often have a rapid transformation to leukemia and should be treated as though they had presented with[r]

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FIBRILLIN-1 (FBN-1) A NEW MARKER OF GERM CELL NEOPLASIA IN SITU

FIBRILLIN-1 (FBN-1) A NEW MARKER OF GERM CELL NEOPLASIA IN SITU

BABAL 1 Abstract Background:Germ cell neoplasia in situ GCNIS, is preinvasive stage of testicular germ cell tumours TGCTs.. Fibrillins, which are integral components of microfibrils are [r]

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