PLANT DERIVED ANTIOXIDANTS AND USE IN PREVENTION AND TREATMENT OF PROSTATE CANCER

10 May 2018Cancer is a major public health burden in both developed and developing countries. Plantderived agents are being used for the treatment of cancer. Plants such as herbs have beenused in folk medicine for centuries in most of th[r]

Although cancer-related fatigue (CRF) has gained increased attention in the past decade, therapy remains a challenge. Treatment programs are more likely to be effective if the needs and interests of the persons involved are well represented.

Jo, et al: Clin J Am Soc Nephrol; 2007, 2:356-365“Earlier” Detection of AKIInduction of NGAL protein after unilateral orbilateral ischemiaMishra, et al: J Am Soc Nephrol; 2003, 14:2534-2543Urinary IL-18 as an Early Marker of AKIIL-18 as a marker for thediagnosis of ATN an[r]

Tumor recurrence and metastasis occur at a high rate in patients with colon cancer. Identification of effective strategies for the treatment of colon cancer is critical. Recently, poly (lactic-co-glycolic acid) (PLGA) has been shown to have potential as a broad therapeutic drug delivery system.

Diabetes mellitus is a metabolic disorder characterized by hyperglycemia and alterations in carbohydrate, fat and protein metabolisms. Diabetes is associated with absolute or relative deficiencies in insulin secretion by pancreatic β-cells and/or insulin action. For the treatment of diabetes large n[r]

In Brief: Generic Celecoxib
The FDA has authorized two manufacturers (Teva, Mylan) to market generic formulations of celecoxib (Celebrex – Pfizer), the only COX-2 selective inhibitor remaining on the US market....
Extended-Release Oxycodone and Acetaminophen (Xartemis XR)
The FDA has approved a f[r]

... 1 .3. 4 Other regulatory mechanisms 30 1 .3. 5 Apoptosis and cancer 30 1 .3. 6 TRAIL signaling pathway as potential therapeutic target 32 Objectives of the study Chapter Materials and Methods 33 34 ... accompanying p 53 up-regulation 51 3. 4 I3M causes Bid cleavage 55 3. 5 I3M induces Bax confor[r]

Hepatocellular carcinoma (HCC) is the leading cause of cancer-related deaths worldwide. The only drug currently approved for clinical use in the treatment of advanced HCC is sorafenib. However, many patients with HCC show reduced sensitivity to sorafenib during treatment.

Breast cancer treatment is tailored to the specific cancer subtype. Often, systemic treatment is given prior to surgery. Chemotherapy induces significant endoplasmic reticulum (ER) stress-mediated cell death and upregulation of 78-kDa glucose-regulated protein (GRP78).

Durlaza - A 24-Hour Extended-Release Aspirin
The FDA has approved Durlaza (New Haven Pharmaceuticals), a 24-hour extended-release (ER) aspirin formulation available only by prescription, for secondary prevention of myocardial...
Fluad - An Adjuvanted Seasonal Influenza Vaccine for Older Adults
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Antioxidants are powerful free radical scavengers in the body, while free radicals are highly reactive chemical substances such as superoxide, hydroxyl radical, or singlet oxygen 1 that travel around in the body and cause damage to body cells. Free radical damage is one of the most prominent causes[r]

Endophytes are known for its novel metabolites and benefits for host. Diversified role of endophytes are being studied in order to enhance their use in agriculture production system. Endophytes are being use for plant growth promotion, alleviation of biotic and abiotic stresses, enhancing agronomic[r]

Colon adenocarcinoma (COAD) is one of the most lethal cancers. It is particularly important to accurately predict prognosis and to provide individualized treatment. Several lines of evidence suggest that genetic factors and clinicopathological characteristics are related to cancer onset and progress[r]

: Patients diagnosed with metastatic castration-refractory prostate cancer (mCRPC) rely on a limited number of therapeutic agents resulting in a median survival of 2–3 years. A subgroup of those patients with mCRPC presents with oligoprogressive disease.

Conservative methods of harvest propagation to develop expansion and yield of vegetationunderneath in diverse ecological threats are lengthy and not triumphant in many cases. Useof expensive injurious agrochemicals and pesticides causes stern danger t[r]

Ramucirumab monotherapy as a second-line treatment for advanced gastric cancer (AGC) prolongs survival compared to the best supportive care. However, in clinical practice, ramucirumab monotherapy is sometimes used as third- or later-line treatment for AGC refractory to fluoropyrimidine and taxanes.

Patients with metastatic renal cell cancer (mRCC) are commonly treated with the tyrosine kinase inhibitor sunitinib, which blocks signalling from vascular endothelial growth factor (VEGF) - and platelet-derived growth factor-receptors, inhibiting development of new blood vessels.

Mucinous adenocarcinoma (MAC) is a distinct type of colorectal cancer (CRC) associated with poor response to treatment and poorer prognosis. MAC is diagnosed by WHO definition when the extracellular mucin is more than 50% of the lesion.

This study examines the use of safeguards or protective behaviours by young adults to
reduce the harm and negative consequences associated with excessive alcohol
consumption. Participants were 210 Australian university students. Participants
completed an online questionnaire which focused on their a[r]

Although docetaxel-based chemohormonal therapy (CHT) is one of the standard treatments for castration-resistant prostate cancer (CRPC), pertinent biomarkers and precise mechanisms involved in the resistance for CHT for CRPC remain unknown.