DIAGNOSTIC VALUE OF C - REACTIVE PROTEIN AND HEMATOLOGICAL MARKERS IN NEONATAL SEPSIS

Late-onset sepsis in very low birth weight (VLBW) infants is a diagnostic challenge. We aimed to evaluate the diagnostic utility of the C-Reactive protein (CRP) and the complete blood count (CBC) for late-onset sepsis in VLBW infants.

Available online http://ccforum.com/content/10/2/134
Abstract
B-type natriuretic peptide (BNP) and amino-terminal pro-BNP (NT- proBNP) are promising cardiac biomarkers that have recently been shown to be of diagnostic value in decompensated heart failure, acute[r]

Two main mechanisms might be responsible for the increase of circulating proADM in infections, including CAP. Firstly, as a member of the calcitonin gene family, ADM is widely expressed and extensively synthesized during severe infec- tions, that is, sepsis, simila[r]

Samira Z. Sayed 1 , Mohamed M. Mahmoud 1 , Hend M. Moness 2 and Suzan O. Mousa 1*
Abstract
Background: Sepsis is still one of the main causes of infants and children mortality especially in developing, economically challenged countries with limited resou[r]

Neonatal septicemia is a clinically diagnosed condition having diverse etiology and changing antibiotic sensitivity pattern. The knowledge of common bacterial agents causing septicemia and their antibiogram is useful in deciding empirical antimicrobial therapy. The neonatal blood cultures were studi[r]

The prognostic value of many inflammation-based scores, such as preoperative C-reactive protein CRP, the Glasgow Prognostic Score GPS, modified Glasgow prognostic score mGPS, high-sensit[r]

In these two nested case–control studies, we found that high plasma levels of C-reactive protein were associated with an increased risk of coronary heart disease among women and men without previous cardiovascular disease. Elevated plasma levels of[r]

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Cachexia may occur in 40% of cancer patients, representing the major cause of death in more than 20% of them. The aim of this study was to investigate the role of leptin, ghrelin and obestatin as diagnostic and predictive markers of cachexia in oncologic patients.

Sepsis is a leading cause of morbidity and mortality among newborns. C-reactive protein (CRP) and procalcitonin (PCT) have some limitations in the diagnosis of preterm neonatal sepsis. In this study, the cut-offs of PCT and CRP, and the efficacy of mean platelet volume (MPV) were investigated.

overall between patients with SLE and matched healthy controls, free protein S was decreased in subsets of SLE patients with a history of serositis, neurologic, hematolo- gic, and immunologic disorder. It was especially note- worthy that the concentrations[r]

Neonatal septicaemia diagnosis based on clinical features alone is non-specific leading to the initiation of unnecessary antibiotic treatment posing a danger of increased antibiotic resistance.

Management. A combined prenatal and postna- tal treatment program for congenital toxoplas- mosis can reduce the neurological morbidity. When seroconversion indicates acute maternal infection, fetal blood and amniotic fluid are cultured and fetal blood is tested for Toxo- plasma[r]

Poor prognosis in gallbladder cancer is due to late presentation of the disease, lack of reliable biomarkers for early diagnosis and limited targeted therapies. Early diagnostic markers and novel therapeutic targets can significantly improve clinical management of gallbladder cancer.

No study has evaluated C-reactive protein (CRP) and plasma albumin (PA) levels longitudinally in patients with acute myeloid leukaemia (AML).

Hemophagocytosis, a phenomenon of which activated macrophages phagocytosed hematopoietic elements was reportedly observed in severe dengue patients. In the present study, we investigated whether markers of macrophage activation syndrome (MAS) can be used as differential diagnostic markers of severe[r]

Đây là chứng tỏ đầu tiên của mục tiêu mới về LDL-C thấp hơn của Chương Trình Giáo Dục Quốc Gia về Cholesterol (National Cholesterol Education Program = NCEP). Cho mỗi nhóm, người ta cứu xét ảnh hưởng trên nguy cơ mắc bệnh tim mạch của mức độ CRP sau khi đ[r]

marker for the severity of MODS, since the correlation of PCT concentrations and score values is weak.
These findings have an impact on the interpretation and design of comparative clinical studies using PCT. When PCT levels are to be compared between different g[r]

There are some potential limitations of this study that warrant further investigation. Experimental data suggest that SAA levels may be affected by nutritional status and hepatic function [4,5]. In addition, infusion of lipid emulsions in parenteral[r]

Neonatal sepsis is one of the most important causes of mortality in developing countries and yet the most preventable. In developing countries clinical algorithms are used to diagnose clinical neonatal sepsis because of inadequate microbiological services.

Neonatal sepsis, one of the leading causes of mortality in neonatal intensive care units (NICU) of developing countries like Nepal, is often not extensively studied. In order to decrease the morbidity and mortality associated with neonatal sepsis, neonatologists should have a keen knowledge of the e[r]