IDENTIFICATION AND APPLICATION OF ANTIINFLAMMATORY COMPOUNDS SCREENING SYSTEM BASED ON RAW264.7 CELLS STABLY EXPRESSING NF-ΚB-DEPENDENT SEAP REPORTER GENE
Tìm thấy 10,000 tài liệu liên quan tới tiêu đề "Identification and application of antiinflammatory compounds screening system based on RAW264.7 cell...":
BÁO CÁO Y HỌC: "HEPCIDIN INDUCES HIV-1 TRANSCRIPTION INHIBITED BY FERROPORTIN" PPS
Iron might be important for different proliferative steps in the life cycle of HIV-1 including reverse-tran- scription, activation of NF- B, regulation of HIV-1 tran- scription, translation of viral mRNA and viral assembly [31]. Previously, Nef, an HIV-1 ac[r]
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THE FUNCTIONAL INVESTIGATION OF FORKHEAD FACTOR FOXQ1 IN HUMAN BREAST AND COLON CANCERS
The ability of FOXO to control cell survival and cell death suggests that FOXO may function as tumor suppressors, and loss of FOXO function has been observed in a number of human cancers. The loss of function maybe due to genetic defects and alter[r]
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CELL METABOLISM CELL HOMEOSTASIS AND STRESS RESPONSE PART 14 POTX
The synthesis and processing of ribosomal RNAs for ribosome production is the most robust gene expression pathway in mammalian cells. Although products of all RNA polymerases are required for final assembly of ribosomes, ribosome biogenesis occurs in nucle[r]
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BÁO CÁO KHOA HỌC: VITAMIN D STIMULATES APOPTOSIS IN GASTRIC CANCER CELLS IN SYNERGY WITH TRICHOSTATIN A ⁄SODIUM BUTYRATE-INDUCED AND 5-AZA-2¢-DEOXYCYTIDINE-INDUCED PTEN UPREGULATION PPT
transcription factors on the promoter. We were therefore interested in determining whether TSA ⁄ - NaBu had any effects on promoting the binding of Egr-1, a major transcription factor of PTEN. To do this, we first examined the influences of TSA and NaBu on<[r]
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CUL4A OVEREXPRESSION AS AN INDEPENDENT ADVERSE PROGNOSTICATOR IN INTRAHEPATIC CHOLANGIOCARCINOMA
OverexpressingCUL4Ain iCCA cell lines alters their migratory and invasive capacitiesin vitro To determine the effects of CUL4A on the mobility of cancer cells, we established two stably [r]
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Ethical and safety issues of stem cell based therapy
Results obtained from completed and on-going clinical studies indicate huge therapeutic potential of stem cell-based therapy in the treatment of degenerative, autoimmune and genetic disorders. However, clinical application of stem cells raises numerous ethical and safety concerns.
BÁO CÁO KHOA HỌC: ATP-BINDING DOMAIN OF HEAT SHOCK PROTEIN 70 IS ESSENTIAL FOR ITS EFFECTS ON THE INHIBITION OF THE RELEASE OF THE SECOND MITOCHONDRIA-DERIVED ACTIVATOR OF CASPASE AND APOPTOSIS IN C2C12 CELLS POTX
Both adherent and floating cells were collected after treat-
ment, washed with ice-cold NaCl ⁄ P i , and stained with
fluorescein isothiocyanate (FITC)-conjugated annexin V
(BD Biosciences, Franklin Lakes, NJ, USA) and pyridine iodination (PI) for 20 min at room tempe[r]
ment, washed with ice-cold NaCl ⁄ P i , and stained with
fluorescein isothiocyanate (FITC)-conjugated annexin V
(BD Biosciences, Franklin Lakes, NJ, USA) and pyridine iodination (PI) for 20 min at room tempe[r]
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DFT and TD-DFT calculation of new thienopyrazine-based small molecules for organic solar cells
Novel six organic donor-π-acceptor molecules (D-π-A) used for Bulk Heterojunction organic solar cells (BHJ), based on thienopyrazine were studied by density functional theory (DFT) and time-dependent DFT (TD-DFT) approaches, to shed light on how the π-conjugation order influence the performance of t[r]
R ECSEOARCUH GARTHICL EOFFICER SCREENING IMPROVES DETECTION OF PULMONARY TUBERCULOSIS IN HOSPITAL IN PATIENTS PPTX
Statistical analysis
Categorical data is presented as numbers with percent- ages and continuous data is presented as medians, with minimums and maximums where appropriate for non- normal distributions. The Wilcoxon rank-sum test was used to assess differences in healthcare system<[r]
Categorical data is presented as numbers with percent- ages and continuous data is presented as medians, with minimums and maximums where appropriate for non- normal distributions. The Wilcoxon rank-sum test was used to assess differences in healthcare system<[r]
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An integrated strategy for identifying new targets and inferring the mechanism of action: Taking rhein as an example
Target identification is necessary for the comprehensive inference of the mechanism of action of a compound. The application of computational methods to predict the targets of bioactive compounds saves cost and time in drug research and development.
BÁO CÁO KHOA HOC CP 31398 A PUTATIVE P53 STABILIZING MOLECULE TESTED IN MAMMALIAN CELLS AND IN YEAST FOR ITS EFFECTS ON P53 TRANSCRIPTIONAL ACTIVITY POTX
We next tested whether CP-31398 might have an effect on endogenous wild type p53 in the human cell line HeLa.
These cells express wild type p53 protein, but p53 levels are low because of the presence of the viral HPV E6 pro- tein, which targets p53 for degradation [15].[r]
These cells express wild type p53 protein, but p53 levels are low because of the presence of the viral HPV E6 pro- tein, which targets p53 for degradation [15].[r]
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Optimal interval of endoscopic screening based on stage distributions of detected gastric cancers
Although Korea and Japan have a national gastric cancer screening program, their screening intervals are different. The optimal screening interval of endoscopic screening in Japan was investigated based on the stage distributions of screen-detected gastric cancers.
MANAGEMENT AND SERVICES PART 8 PPTX
This architecture in the pilot platform consists of 3 tiers (as illustrated in Fig. 4): Client side, Catalog side and Server side. Catalog side is a multi-level tree structure. The top node is a
UDDI Catalog Server of Southwestern China, which owns several children nodes, Gu[r]
UDDI Catalog Server of Southwestern China, which owns several children nodes, Gu[r]
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BÁO CÁO KHOA HỌC: A NEW MOLECULAR TOOL FOR TRANSGENIC DIATOMS CONTROL OF MRNA AND PROTEIN BIOSYNTHESIS BY AN INDUCIBLE PROMOTER–TERMINATOR CASSETTE DOCX
Cloning of the CfNR gene
Extraction of poly(A)-rich RNA from C. fusiformis and synthesis of cDNA coupled to oligo(dT) 25 magnetic beads (Dynal Biotech, Hamburg, Germany) was as described [9]. Degenerate oligonucleotides NR1 (5 ¢ -TGGTGGTAYAAR CCNGANT-3 ¢ ) and[r]
Extraction of poly(A)-rich RNA from C. fusiformis and synthesis of cDNA coupled to oligo(dT) 25 magnetic beads (Dynal Biotech, Hamburg, Germany) was as described [9]. Degenerate oligonucleotides NR1 (5 ¢ -TGGTGGTAYAAR CCNGANT-3 ¢ ) and[r]
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Particle identification for Z = 25 – 28 exotic nuclei from seastar experimental data
The particle identification (PID) method based on TOF-Bρ-ΔE measurement at RIKEN are discussed, and its application for Z = 25 – 28 neutron-rich nuclei from SEASTAR (Shell Evolution And Search for Two-plus energy At RIBF) experimental data are presented.
Summary Of Chemistry Doctoral Thesis: Study on chemical constituents and biological activities from the tubers of Ophiopogon Japonicus (L.F.) KER-GAWL
The research objectives of the dissertation isolate and determine the structure of clean compounds from mondo grass root roots. Evaluate cytotoxic effects and anti-inflammatory activity based on the effect of inhibiting NO production of isolated compounds.
Summary Of Chemistry Doctoral Thesis: Study on chemical constituents and biological activities from the tubers of Ophiopogon Japonicus (L.F.) KER-GAWL
The research objectives of the dissertation isolate and determine the structure of clean compounds from mondo grass root roots. Evaluate cytotoxic effects and anti-inflammatory activity based on the effect of inhibiting NO production of isolated compounds.
TÀI LIỆU PURSUING WIRELESS EXCELLENCE AT CEDARS-SINAI MEDICAL CENTER PPTX
The DWOS system gave us instant communications and greatly increased peoples’ efficiency.” Based on pico cells individual, ceiling-mounted cellular radios, the DWOS system improved cellu[r]
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BÁO CÁO KHOA HỌC: AMINO ACIDS THR56 AND THR58 ARE NOT ESSENTIAL FOR ELONGATION FACTOR 2 FUNCTION IN YEAST POTX
Construction of plasmid for counter selection
Vector pYES3 ⁄ CT was digested with restriction enzymes
Aat II and Cla I to remove the TRP1 gene. The digestion products were separated by agarose gel-electrophoresis and the vector without TRP1 was isolated. The HIS3 g[r]
Vector pYES3 ⁄ CT was digested with restriction enzymes
Aat II and Cla I to remove the TRP1 gene. The digestion products were separated by agarose gel-electrophoresis and the vector without TRP1 was isolated. The HIS3 g[r]
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MICRORNA-141 INHIBITS CELL PROLIFERATION AND INVASION AND PROMOTES APOPTOSIS BY TARGETING HEPATOCYTE NUCLEAR FACTOR-3Β IN HEPATOCELLULAR CARCINOMA CELLS
For the luciferase reporter assays, HepG2 cells were cultured in 24-well plates, and cells in each well were transfected with 1μg of firefly luciferase reporter plasmid, 1μg of aβ-galact[r]
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