Leiomyosarcoma (LMS) is an aggressive soft tissue sarcoma derived from smooth muscle cells typically of uterine, gastrointestinal or soft tissue origin. The prognosis for this tumor is poor, with survival rates among the lowest of all soft tissue sarcomas. Surgery is the best approach for localized[r]
A Tzanck smear is a cytologic technique most often used in the diagnosis of herpesvirus infections [herpes simplex virus (HSV) or varicella zoster virus (VZV)] (see Figs. 173-1 and 173-3). An early vesicle, not a pustule or crusted lesion, is unroofe[r]
Focal adhesion Kinase (FAK) is a nonreceptor protein tyrosine kinase that is overexpressed in tumors and plays a significant role in tumor survival and metastasis. The purpose of the study is to perform correlation of FAK expression with patient prognostic factors using tissue microarrays (TMA) samp[r]
The aim of the trial is to demonstrate that with the use of modern IMRT/IGRT and reduction of safety margins postoperative wound complications can be reduced. The present study protocol prospectively evaluates the use of IMRT/IGRT for neoadjuvant RT in patients with soft tissue sarcomas of the extre[r]
Seroma formation is a common complication after mastectomy and is associated with delayed wound healing, infection, skin flap necrosis, patient discomfort and repeated visits to the out patient clinic to deal with seroma and its sequelae.
To report the results of a subgroup analysis of a prospective phase II trial focussing on radiation therapy and outcome in patients with extremity soft tissue sarcomas (STS). Methods: Between 2005 and 2010, 50 patients (pts) with high risk STS (size ≥ 5 cm, deep/extracompartimental location, grade I[r]
Scientists then extract stem cells from the ball of divided cells, and use those cells to grow tissue which is a perfect genetic match for the patient.. The cells created by therapeutic [r]
Infantile myofibromatosis belongs to a family of soft tissue tumors. The majority of these tumors have benign behavior but resistant and malignant courses are known, namely in tumors with visceral involvement. The standard of care is surgical resection. Observations suggest that low dose chemotherap[r]
Four basic features of a skin lesion must be noted and considered during a physical examination: the distribution of the eruption, the types of primary and secondary lesions, the shape o[r]
Social, sexual, or travel history as relevant to the patient DIAGNOSTIC TECHNIQUES Many skin diseases can be diagnosed on gross clinical appearance, but sometimes relatively simple diagn[r]
The number of people living with soft-tissue and bone sarcomas is increasing due to improved individual therapy and changes in demographics. At present, there are no recommendations for psychological cotreatment, occupational and social reintegration following the treatment of soft tissue and bone s[r]
We retrospectively reviewed outcomes of treatment with pazopanib, an oral multi-tyrosine kinase angiogenesis inhibitor, in patients with advanced soft tissue sarcoma, a rare and heterogeneous tumor group with limited treatment options.
Dermatophytes are among the common fungal agents implicated in superficial skin infections worldwide. Infections commonly occur in hot and humid climates. They include species of Trichophyton, Microsporum and Epidermophyton. The present study was done to assess the clinical profile of dermatophytic[r]
... support and understanding I would also like to thank Dr Yen Shih Cheng and A/Prof Gerald Koh for their patient explanation of concepts and timely pointers I am grateful to Ms Karen Koh and Angela... has also been a pleasure to work with Mr Benjamin Hon and Mr Phan Shi Wen who developed and maint[r]
Ewing sarcoma is an aggressive, highly metastatic primary bone and soft tissue tumor most frequently occurring in the bone of young adolescents. Patients, especially those diagnosed with a metastatic disease, have a poor overall survival.
Progressive bone pain and fracture and abnormal positron emission tomography combined with a computed tomography are main reasons for the oncologists suspecting bone tumor. During the patient’s medical treatment, the oncologists’ unfamiliarity with adverse reactions to anti-HBV drugs were main reaso[r]
However, other modalities, including antitumor therapy such as surgical relief of obstruction, radiation therapy, and strontium-89 or samarium-153 treatment for bone pain, neurostimulato[r]
Maintenance must be performed in order to: • Correct faults • Improve the design • Implement enhancements • Interface with other systems • Adapt programs so that different hardware, soft[r]
Metastasis to the breast from nonmammary malignancies is rare, and mostly involves patients in a pre-terminal condition with systemic metastases outside the breast. Lymphoma and leukemia, melanoma, and lung carcinoma are the most common primary malignancies to cause breast metastasis; metastasis of[r]
perfringens_ is the most common of the clostridial species isolated from tissue infections and bacteremias; next in frequency are _C.. In the category of enteric infections, _C.[r]