INDUCED O ACYLATION OF SIDE CHAIN HYDROXYLS AND THE O TO N ACYL SHIFT

tion-related cDNA from Phalaenopsis encoding a protein whichis homologous to human peroxisomal acyl-CoA oxidase. Arch.Biochem. Biophys. 344, 295–300.7. Pedersen, J.I. (1993) Peroxisomal oxidation of the steroid sidechain in bile acid formation. Biochimie 75, 159–165.8. Pedersen,[r]

findings and showed the presence of 2,6-dideoxy-4-O-methyl-2-(N-methylacetamido)-glucose and 3,6-dideoxy-2-O-methyl-3-( N-methylacetamido)-glucose, in accordancewith the proposed structure of C PS. T he linkage ofGalNAcA could not[r]

protein for membranes, which can thereby affect theprotein’s localization and function. This is the case forboth solely palmitoylated proteins and dually lipidatedproteins. This raises the question of why a protein withone lipid modification needs a second lipid mod[r]

1 Introduction and ObjectivesPolysaccharides are unique biopolymers with an enormous structural diversity.Huge amounts of polysaccharides are formed biosynthetically by many organ-isms including plants, animals, fungi, algae, and microorganisms as storage poly-mers and st[r]

There is a great deal of confusion regarding exactly what supply chain management (SCM) involves. In fact, most people using the name supply chain management treat it as a synonym for logistics or as logistics that includes customers and suppliers. However, successful SCM requires crossfunctional in[r]

side chain oxygen atoms on the phosphorus atom of thesubstra te phosph oserine .Keywords: calcium; HAD superfamily; magnesium-depend-ent enzymes; phosphoserine phosphatase;L-serine.Human phosphoserine phosphatase (HPSP) catalyses thelast and irreversible step of[r]

important in the signal transduction mechanism.Although a conserved salt bridge exists between Glu59and Ly s104 in Ec DOS [ 4], the roles of these amino acidsremain to be elucidated. In Ec DOS, Asp40–Arg85 saltbridges (Fig. 1) appear to be important for catalyticcontrol.[r]

Bloom, 1984). Faculty Capabilities (FC): Faculty members establish good communication, provide rich environment for classroom observation, model best practices, create opportunities for reflection, and support students' participation in curriculum planning, teaching and research. Tradi[r]

may serve as an indicator of the protein redox state,the mechanism of this change is currently unknown.Its elucidation will require a comparison of the presentstructure with a model of the oxidized molecule deter-mined at comparably high resolu[r]

Hunt AH, Daupert VM, Counter FT, Ott JL, CarrellCB, Howard LC et al. (1988) Enzymatic and chemicalmodifications of lipopeptide antibiotic A21978C: thesynthesis and evaluation of daptomycin (LY146032).J Antibiot 41, 1093–1105.11 Schwarzer D, Finking R & Marahiel MA[r]

two canonical binding loops, both consisting of nine highly conserved resi-dues capable of inhibiting corresponding serine proteases. In this study, wecloned the cDNA of the mung bean trypsin inhibitor, one of the most studiedBowman–Birk protease inhi[r]

ably control the access to the catalytic pocket.To further explore the broad specificity of PhnItowards high molecular weight PAHs a benz[a]antra-cene molecule was overlaid to the PhnI substrate bind-ing pocket. The three most favorable orientations, eachFig.[r]

the new NP brackets.We also ran an experiment where the new NML andJJP labels were relabelled as NP and ADJP. Theseare the labels that would be given if NPs were orig-inally bracketed with the rest of the Penn Treebank.This meant the model woul[r]

CHAPTER 31 MANIPULATING BITS// parity_t.cpp: Defines the function parity(), which// computes the parity of an unsigned// value.// Returns: 0, if the number of 1-bits is even,// 1 in all other cases.// inline unsigned int bit0( unsigned int x ){return (x & 1[r]

limiting structures of a few hundred molecules, bilayers may form spontaneously overlarge areas (108nm2or more). Because exposure of the edges of the bilayer to solventis highly unfavorable, extensive bilayers normally wrap around themselves and formclosed v[r]

20 kDa (aligned from the N-terminus in this order) [21] thatremain tightly associated under nondenaturing conditions.This cleavage occurs at two flexible surface loops: the firstloop, termed loop 1, is located near the active site of myosinATPase at the 25 kDa[r]

Tension pneumothorax Tension pneumothorax is the accumulation of air under pressure in the pleural space. This condition develops when injured tissue forms a 1-way valve, allowing air to enter the pleural space and preventing the air from escaping naturally[r]

with the PM marker Gpa1p (Fig. 7C; yellow areas corres-pond to regions where the red and green signals aresuperimposed), suggesting that most of the CYP11A1antigen resides in the PM. There was no overlap between thered and green signals corresponding[r]

Hypertension 41, 1096–1101.30 Sommerburg O, Grune T, Ehrich JH & Siems WG(2002) Adaptation of glutathione-peroxidase activity tooxidative stress occurs in children but not in adultpatients with end-stage renal failure undergoing hemod-ialysis. Clin Nephrol 58(Suppl 1), S31–S36.[r]

17. Biochemist Joseph Owades revolutionized the production of beerin the United States by developing a simple treatment with an en-zyme that converted regular beer into “light beer,” which was mar-keted aggressively as a beverage that “tastes great,” even though it is“less fillin[r]