DNA DAMAGE RESPONSE AND MUTAGENESIS IN MOUSE EMBRYONIC STEM CELLS PDF

.. .EFFECTS OF HIGH GLUCOSE CONCENTRATIONS ON THE EXPRESSION OF GENES INVOLVED IN PROLIFERATION AND CELL- FATE SPECIFICATION OF MOUSE EMBRYONIC NEURAL STEM CELLS FU JIANG (MD, MMed) A THESIS... Illustration Schematic summary of the effects of high glucose on the expression of developmental control g[r]

.. .GENERATION OF PORCINE INDUCED PLURIPOTENT STEM CELLS AND THEIR DIFFERENTIATION INTO CARDIAC LINEAGES TAN WAN CHIU GRACE (B.Eng.(Hons.), NTU) A THESIS SUBMITTED FOR THE DEGREE OF MASTER OF. .. generate porcine induced pluripotent stem cells (IPSCs) from porcine fibroblast cells and differentiate[r]

Scientists take stem cells from an aborted foetus fortheir research. Is this acceptable?2A two-year-old boy has a rare blood disease andneeds a blood donor to save him. None of hisbrothers’ or sisters’ blood is an exact match.Through genetic diagnosis, scientists are able to tellthe pa[r]

Adult stem cells are crucial for maintaining proper function and repair of tissues. The epithelium of the adult mammalian intestine is a constant dialog with its underlying mesenchyme to direct progenitor proliferation, lineage commitment, terminal differentiation and ultimately cell death. The epit[r]

... damaging and telomeretelomerase effects and hence the mechanism of action of TQ in breast cancer cells In addition, it is of interest to investigate the effects of TQ in normal breast epithelial cells. .. Black cumin seeds (left) and chemical structure of thymoquinone (right) 23 Figure 10 Growth[r]

The enrichment of cancer stem cell-like cells (CSCs) has been considered to be responsible for tumor progression after an initial response to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (EGFR-TKIs) in patients with non-small cell lung adenocarcinoma (NSCLC/ADC). CSCs with ALDH[r]

... Investigation of DNA damage as a potential mechanism of influenza pathogenesis 66 3.1.2 Phosphorylation of H2AX (Ser-139) during DNA strand breaks 69 3.1.3 DNA damage is triggered by influenza. .. to sense for DNA damages, activate cell signaling and repair DNA lesions DNA damage are surveyed v[r]

Antioxidants are powerful free radical scavengers in the body, while free radicals are highly reactive chemical substances such as superoxide, hydroxyl radical, or singlet oxygen 1 that travel around in the body and cause damage to body cells. Free radical damage is one of the most prominent causes[r]