TOCOPHEROL AS ANTI-OXIDANT

Oxford Centre for Gene Function, University Department of Physiology, Anatomy & Genetics, Parks Rd, Oxford OX1 3PT, UKEmail: Luisa Minghetti* - luisa.minghetti@iss.it; Anita Greco - agreco@iss.it; Maria Puopolo - mpuopolo@iss.it; Marc Combrinck - mcombrin@uctgsh1.uct.ac.za; Donald Warden - d[r]

zum, J.L. (1989) Beyond cholesterol: modifications of low-densitylipoprotein that increase its atherogenicity. N.Engl.J.Med.320,915–924.9. Witzum, J.L. (1994) The oxidation hypothesis of atherosclerosis.Lancet 344, 793–795.10. Bors, W., Michel, C. & Saran, M. (1994) Flavonoid antioxidants:rat[r]

MSR cells transiently transfected with DAT and p25a, a-syn or theempty vector were either extracted directly in lysis buffer or sub-jected to cell surface biotinylation with EZ-Link Sulfo-NHS-SS-Biotinfollowed by extraction. This cross-linker allows cleavage betweenbiotin and the target by reducing[r]

Increasing studies implicate cancer stem cells (CSCs) as the source of resistance and relapse following conventional cytotoxic therapies. Few studies have examined the response of CSCs to targeted therapies, such as tyrosine kinase inhibitors (TKIs). We hypothesized that TKIs would have differential[r]

Vascular endothelial growth factor (VEGF) isoforms, particularly the diffusible VEGF-121, could play a major role in the response of recurrent glioblastoma (GB) to anti-angiogenetic treatment with bevacizumab.

CCP in other diseases has been less well studied. Pa-tients with certain infectious diseases, such as hepatitis Cand tuberculosis (TB), can present with arthritis andfrequently also have serum RF, making it difficult todistinguish infectious disease–related arthritis from RA.Thus, the utility[r]

Flavones found in plants display various biological activities, including anti-allergic, anti-viral, anti-inflammatory, anti-oxidation, and anti-tumor effects. In this study, we investigated the anti-tumor effects of flavone, apigenin and luteolin on human breast cancer cells.

88. This year our company sold ______________ magazine subscriptions than ever before.a. lessb. lesserc. fewd. fewerFor more material and information, please visit Tai Lieu Du Hoc at www.tailieuduhoc.orgPage 22SET 8 (Answers begin on page 126.)Replace the underlined portion with the word or phrase t[r]

Glioma is the most common primary malignant central nervous system tumor in adult, and is usually not curable due to its invasive nature. Establishment of serum biomarkers for glioma would be beneficial both for early diagnosis and adequate therapeutic intervention.

Baicalein is a widely used Chinese herbal medicine derived from Scutellaria baicalenesis, which has been traditionally used as anti-inflammatory and anti-cancer therapy. In this study we examined the anti-tumour pathways activated following baicalein treatment in non-small cell lung cancer (NSCLC),[r]

Cholangiocarcinoma is characterized by late diagnosis and a poor survival rate. MicroRNAs have been involved in the pathogenesis of different cancer types, including cholangiocarcinoma. Our aim was to identify novel microRNAs regulating cholangiocarcinoma cell growth in vitro and in vivo.

delayed viral production following exposure to Akt inhib-itor and stress (SNP) was related to the induction of celldeath in HIV-1 infected macrophages. For this test, wequantified cell death under four experimental conditionsusing the Live/Dead assay (Figure 1E). This assay uses flu-orescent dyes wh[r]

Betulinic acid (BA), a member of pentacyclic triterpenes has shown important biological activities like anti-bacterial, anti-malarial, anti-inflammatory and most interestingly anticancer property.

in the skin are unaffected by control of disease with medication; however, these immunoreactants may diminish in intensity or disappear in patients maintained for long periods on a strict gluten-free diet (see below). Patients with DH have granular deposits of IgA in their epidermal basement membran[r]

To study the effect of different temperature and photoperiod regimes on tocopherol content, seventeen photo and thermo tolerant soybean genotypes were planted under three planting dates viz., March 1(D1), June 5 (D2) and August 7 (D3). Analysis of variance revealed significant differences for genoty[r]

Tumour stromal macrophages differentiate to tumour-associated macrophages (TAMs) with characteristics of immunosuppressive M2-type macrophages, having a central role in promoting tumour vascularisation, cancer cell dissemination and in suppressing anti-cancer immune responses. Bisphosphonates (BPs)[r]

homogeneous cells containing hyperchromatic nuclei. Basal keratinocytes remain attached to the epidermal basement membrane, hence blister formation is within the suprabasal portion of the epidermis. Lesional skin may contain focal collections of intraepidermal eosinophils within blister cavities; de[r]

Increasingly, the role of chronic inflammation and its mediators in tumor generation and progression is gaining importance in the field of cancer research. In this context, candidature of non steroidal anti-inflammatory drugs (NSAIDs) as potential anti-tumor therapeutic agent is being evaluated glob[r]

Thomalla, G., Glauche, V., Koch, M., Beaulieu, C., Weiller, C., & Rother, J. (2004). Diffusion tensor imaging detects early Wallerian degeneration of the pyramidal tract after ischemic stroke. NeuroImage, Vol. 22, No. 4, pp. (1767–1774). Thornton, P., McColl, B. W., Greenhalgh, A., Denes, A.[r]

Former studies already revealed the anti-neoplastic properties of the anti-infective agent Taurolidine (TRD) against many tumor species in vitro and in vivo. Its anti-proliferative and cell death inducing capacity is largely due to its main derivative Taurultam (TRLT).