The fluorescence-activated cell sorting FACS analysis showed that the loss of _udu_ TRANG 11 TRANG 12 xi LIST OF TABLES TABLE 2.1 LIST OF MOLECULAR MARKERS USED IN THIS STUDY 56 TABLE 2.[r]
Results Endothelial cell-secreted factors activate key signaling pathways in tumor cells We have previously demonstrated that a crosstalk initi- ated by endothelial cells enhances tumor cell survival and migration in vitro, and that endothelial cell-deri[r]
Relationships among cancer stem cell subsets Up to now, precancerous stem cells, primary cancer stem cells and migrating cancer stem cells have been proven to exist in the progression of[r]
Binding of mAb 56.3 to intracellular calpain revealed by confocal microscopy and fluorescence quantification Control or stimulated MEL cells, Jurkat cells or human neu-trophils were wash[r]
dysfunction [7,10-12]. Indeed, the therapeutic potential of MSC has been extensively investigated using animal models of kidney disease [7,10,11,13]. Interestingly, although several experimental studies [6,7,10,11,13-15] have established the role of MSC therapy in preserving r[r]
There is extensive evidence for the role of aberrant cell survival signaling mechanisms in cancer progression and metastasis. Akt is a major component of cell survival-signaling mechanisms in several types of cancer. It has been shown that activated Akt stabilizes XIAP by S87 phosphorylation leading[r]
Isolation of Mesenchymal Stem Cell from Wharton’s Jelly of Human Umbilical Cord for Application in Wound Healing2. Nguyen Thi Bich 1 , Bui Thi Van Khanh 1 , Truong Linh Huyen 2 , Chu[r]
Cancer stem cells are hypoxia-resistant and present a preponderant glycolytic metabolism. These characteristics are also found in basal-like breast carcinomas (BLBC), which show increased expression of cancer stem cell markers.
Conventional chemotherapy in malignant pleural mesothelioma (MPM) has minimal impact on patient survival due to the supposed chemoresistance of cancer stem cells (CSCs). We sought to identify a sub-population of chemoresistant cells by using putative CSC markers, aldehyde dehydrogenase (ALDH) and CD[r]
Neuroendocrine cells (NECs) reside adjacent to colonic stem cells (SCs) in the crypt stem cell (SC) niche, but how NECs are involved in regulation of SCs is unclear. We investigated NECs expressing somatostatin (SST) and somatostatin receptor type 1 (SSTR1) because SST inhibits intestinal proliferat[r]
.. .GENERATION OF PORCINE INDUCED PLURIPOTENT STEM CELLS AND THEIR DIFFERENTIATION INTO CARDIAC LINEAGES TAN WAN CHIU GRACE (B.Eng.(Hons.), NTU) A THESIS SUBMITTED FOR THE DEGREE OF MASTER OF. .. generate porcine induced pluripotent stem cells (IPSCs) from porcine fibroblast cells and differentiate[r]
(See figure on previous page.) Figure 1 HNSCC cell lines contain cell populations with low proteasome activity and higher sphere-forming capacity. HNSCC cell lines were engineered to express the fusion protein ZsGreen and the c-terminal of the degron ornithine decarboxy[r]
mechanism similar to that of NO-ASA, i.e., release of a QM depleting intermediate [23]. OPH (EC 3.4.19.1), also called acylamino acid releasing enzyme (or AARE), is a serine esterase/protease that we found to be over expressed in some tumorigenic prostate cell lines [24]. More[r]
Caldesmon (CaD), a major actin-associated protein, is found in smooth muscle and non-muscle cells. Smooth muscle caldesmon, h-CaD, is a multifunctional protein, and non-muscle cell caldesmon, l-CaD, plays a role in cytoskeletal architecture and dynamics.
restriction to one single model system, namely Arabidopsis thaliana. The root of this species has all it needs to guarantee easy laboratory handling and experimentation. On top of this, its genome is sequenced and a myriad of molecular tools have become available. In the fir[r]
Scientists then extract stem cells from the ball of divided cells, and use those cells to grow tissue which is a perfect genetic match for the patient.. The cells created by therapeutic [r]
determining body patterning in invertebrates. HoxB4 is capable of inducing extensive self-renewal of stem cells through its DNA-binding motif. Other members of the hox family of genes have been noted to affect normal stem cells[r]
ES cells self-renew endlessly so that a single cell line with carefully characterized traits can generate large numbers of cells that can be immunologically matched with potential transplant recipients. However, little is currently known ab[r]
Cell Differentiation and Embryonic Development BIO101 - Bora Zivkovic - Lecture 2 - Part 2 There are about 210 types of human cells, e.g., nerve cells, muscle cells, skin cells, blood cells, etc. Wikipedia has a nice comprehensive listin[r]