ANATOMY PHYSIOLOGY AND PATHOGENESIS OF PROSTATE CANCER

African Americans have disproportionately higher burden of prostate cancer compared to European Americans. However, the cause of prostate cancer disparities is still unclear. Several roles have been proposed for calcium and vitamin D in prostate cancer pathogenesis and progression, but epidemiologic[r]

modulated during human melanoma differentiation, growth andprogression. Oncogene 1995, 11:2477-2486.17. Jiang H, Su ZZ, Lin JJ, Goldstein NI, Young CSH, Fisher PB: The melanomadifferentiation associated gene mda-7 suppresses cancer cell growth.Proc Nat Acad Sci USA 1996, 93:9160-9165.18. Lebe[r]

This Provisional PDF corresponds to the article as it appeared upon acceptance. Fully formattedPDF and full text (HTML) versions will be made available soon.Downregulation of APOBEC3G by Xenotropic Murine Leukemia-Virus RelatedVirus (XMRV) in Prostate Cancer CellsVirology[r]

Platinum-based chemotherapy is emerging as the first line of treatment for castration resistant prostate cancer. Among the family of platinum (IV)-based compounds, a member known as CPA-7 inhibits the growth of multiple cancer cell lines. However, how and to what extent CPA-7 elicits its anti-prosta[r]

Why?Answer: HCl ionizes to form current-conducting electrolytes. Dextrose does not ionize, andtherefore does not conduct current.Diff: 3 Page Ref: 3522) Describe the factors that affect chemical reaction rates.Answer: Temperature increases kinetic energy and therefore the force of mole[r]

Prostate cancer patients are known to suffer from poor sexual and urinary long-term side-effects following treatment, potentially impacting quality of life. The purpose of our study was to compare health-related quality of life at 3 years between prostate cancer patients and healthy controls accordi[r]

modulated during human melanoma differentiation, growth andprogression. Oncogene 1995, 11:2477-2486.17. Jiang H, Su ZZ, Lin JJ, Goldstein NI, Young CSH, Fisher PB: The melanomadifferentiation associated gene mda-7 suppresses cancer cell growth.Proc Nat Acad Sci USA 1996, 93:9160-9165.18. Lebe[r]

H3K27me3 histone marks shape the inhibition of gene transcription. In prostate cancer, the deregulation of H3K27me3 marks might play a role in prostate tumor progression. Our findings point to epigenetic mark H3K27me3 as an important event in prostate carcinogenesis and progression. The results repo[r]

function of cotyledon*Seed dry weight as % fresh weightProbable germination pattern+Climate of original habitat1 Malvaceae 60% Tropical / wet2 Moraceae 45% Tropical / wet3 Malvaceae 80% O Tropical-Subtropical / dry4 Sapindaceae 65% R Tropical / wet5 Pinaceae P 80% Temperate / subtropic[r]

To evaluate the impact of Gallium-68 [68Ga] labeled prostate specific membrane antigen (PSMA) positron emission tomography (PET)/X-ray computed tomography (CT) compared with conventional imaging on staging and clinical management of men evaluated for primary prostate cancer (PCa).

Inflammation plays an important role in the pathogenesis of ovarian cancer. This study sought to investigate the association between the preoperative c-reactive protein/albumin ratio (CRP/Alb) and oncological outcomes in ovarian cancer patients.

EDITOR’S INTEGRATIONThere are other important examples of structures “within” our body that, like the urinaryspace, actually represent extensions of the outside world. The respiratory tract, fromthe nasal and oral openings down to the alveoli, and the gastrointestinal tra[r]

Prostate and breast cancer can have a lot of negative consequences such as fatigue, sleep difficulties and emotional distress, which decrease quality of life. Group interventions showed benefits to emotional distress and fatigue, but most of these studies focus on breast cancer patients.

Prostate cancer is the most commonly diagnosed cancer in north-American men. Few dietary or lifestyle interventions have been tested to prevent prostate cancer progression. Omega-3 fatty acid supplementation represents a promising intervention for prostate cancer patients.

failed to detect the virus in cohorts of prostate cancer patients [5-9]. Very recently, Paprotka et al. (2011) have challenged an association of XMRV with human diseases [10]. These authors have reported that XMRV may have originated by a rare recombination event during t[r]

One common screening method involves ablood test for prostate-specific antigen (PSA).Elevated levels of this antigen, normally present inlow concentrations, may indicate the presence ofprostate cancer. This test is more sensitive thanthe serum enzyme assay previously used forscr[r]

There is ongoing debate about the harms and benefits of a national prostate cancer screening programme. Several model-based cost-effectiveness analyses have been developed to determine whether the benefits of prostate cancer screening outweigh the costs and harms caused by over-detection and over-tr[r]

Few studies have taken risk of competing events into account when examining the relationship between cholesterol and prostate cancer incidence, and few studies have a follow-up over several decades. We aimed to use these approaches to examine the relationship between cholesterol and prostate cancer.

Invasive cribriform and intraductal carcinoma (CR/IDC) is associated with adverse outcome of prostate cancer patients. The aim of this study was to determine the molecular aberrations associated with CR/IDC in primary prostate cancer, focusing on genomic instability and somatic copy number alteratio[r]

INTRODUCTION

Prostate cancer is the 2
nd
most common cancer and the 5
th
most
common death rate for men worldwide. The definitive diagnosis should
be based on digital rectal examination (DRE), serum PSA, prostate
biopsy results. Biopsy plays a decisive role in diagnosis of prostate
can[r]