SMALL CELL LUNG CANCER SPREAD TO BONES AND LIVER

The aim of this study was to gain further investigation of non-small cell lung cancer (NSCLC) tumorigenesis and identify biomarkers for clinical management of patients through comprehensive bioinformatics analysis.

Correct identification of the EGFR c.2369C>T p.(Thr790Met) variant is key to decide on a targeted therapeutic strategy for patients with acquired EGFR TKI resistance in non-small cell lung cancer. The aim of this study was to evaluate the correct detection of this variant in 12 tumor tissue specimen[r]

The prognostic significance of TP53 concurrent mutations in patients with epidermal growth factor receptor (EGFR)- or anaplastic lymphoma kinase (ALK)- mutated advanced non–small-cell lung cancer (NSCLC) who received EGFR-tyrosine kinase inhibitors (TKIs) or ALK-TKIs based targeted therapy remains c[r]

The objective of this study was to investigate real-world EGFR mutation testing in patients with metastatic non-small cell lung cancer (NSCLC) upon progression on first−/second-generation epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKI), and subsequent treatments received.

The enrichment of cancer stem cell-like cells (CSCs) has been considered to be responsible for tumor progression after an initial response to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (EGFR-TKIs) in patients with non-small cell lung adenocarcinoma (NSCLC/ADC). CSCs with ALDH[r]

In Brief: Generic Celecoxib
The FDA has authorized two manufacturers (Teva, Mylan) to market generic formulations of celecoxib (Celebrex – Pfizer), the only COX-2 selective inhibitor remaining on the US market....
Extended-Release Oxycodone and Acetaminophen (Xartemis XR)
The FDA has approved a f[r]

molecular chaperones. Cold Spring Harbor Laboratory Press,Cold Spring Harbor, NY, pp 533–5524. Mestril R, Dillmann WH (1995) Heat shock proteins and protection against myocardial ischemia. J Mol Cell Cardiol 27:45–525. Buchner J (1999) hsp90 and Co.—a holding for folding. Trends[r]

INTRODUCTION OF THESIS

1. Background:
Lung cancer is one of the common cancers. The disease has the highest incidence and mortality among cancers, most commonly seen in the elderly especially over 60 years old. The majority of lung cancer is related to secondhand and passive smoking and has over[r]

Topic 1: What can you do can’t you do in some public places in your towncity country ?
Public places are ones where there are a lot of people. So we should observe the rules here.
Firstly, we must not smoke. It is the fact that smoking is harmful and may cause lung cancer. Moreover, the fact that y[r]

Chapter 02 - Cells, Tissues, Organs, and Organ Systems of Animals27. Small hydrophilic molecules such as ____________ are sometimes able to enter a cellthrough an aquaporin.A. glycerolB. cholesterolC. glucoseD. beta caroteneE. vitamin DBlooms Level: 2. UnderstandLearning Outcome[r]

... of “conflicting theories” in the literature The objective of this thesis is therefore to seek a unifying understanding of the reaction mechanisms for the electrooxidation of small oxygenates... general, the more observations that could be explained by the unifying mechanism, the stronger is the[r]

Patients with metastatic renal cell cancer (mRCC) are commonly treated with the tyrosine kinase inhibitor sunitinib, which blocks signalling from vascular endothelial growth factor (VEGF) - and platelet-derived growth factor-receptors, inhibiting development of new blood vessels.

To investigate histopathological and ultrastructural damages of liver in dioxinexposed people with chronic liver diseases in Vietnam.

Neoadjuvant therapy plus oesophagectomy has been accepted as the standard treatment for patients with potentially curable locally advanced oesophageal cancer. No completed randomized controlled trial (RCT) has directly compared neoadjuvant chemotherapy and neoadjuvant chemoradiation in patients with[r]

In the wake of an unprecedented period of mobile technology dissemination
in developing countries, notably through the use of cell phones and other
information and communication technology (ICT) innovations, it has become
possible to use those technologies to eliminate or greatly reduce barriers to[r]

Cervical cancer mainly caused by human papilloma virus infection, is the leading cancer in Indian women and the second most common cancer in women worldwide. Almost 80% of cases occurred in developing countries. The objectives of the study were to assess the knowledge, attitude regarding cervical ca[r]