CELLULAR AND MOLECULAR MECHANISMS OF CAROTENOID ACTION

Little is known concerning the cellular and molecular mechanisms that sustain sperm within the SST lumen for prolonged periods of storage. These mechanisms likely involve the rever‐ sibl[r]

Protein oxidation is an early event of CS exposure
Earlier we had shown that when guinea pigs fed 1 mg vita- min C/day were exposed to CS, there was progressive for- mation of protein carbonyl on and from the first day of CS exposure at an exposure rate of 5 ci[r]

6. Second-stage fusion (late differentiation)
Growth and maturation of the muscle cells are achieved through a second-stage fusion, which occurs between the nascent myofibers/myotubes and myoblasts. Although many regulators of this fusion process have been revealed i[r]

Primitive Motile Systems in Cell Biology , the field has moved from the phenomeno- logical to the mechanistic and from the largely structural to the primarily molecu- lar. We have come to appreciate that at every level of complexity the cell operates through molecular machines.[r]

various Government agencies) and around 30 projects involving support from industry [Vijayan and Padmanabhan, personal communication].
The National Institute of Immunology (NII), New Delhi created in 1986 is extensively engaged in studies to understand mechanisms[r]

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Long non-coding RNAs play an important role in tumorigenesis, hence, identification of cancerassociated lncRNAs and investigation of their biological functions and molecular mechanisms are important for understanding the development and progression of cancer.

Masson pine (Pinus massoniana) is one of the most important timber species with adaptable, fast growing, versatile advantages in southern China. Despite considerable research efforts, the cellular and molecular mechanisms of A1 toxicity and resistance in P. massoniana are still poorly understood.

doi:10.1111/j.1742-4658.2009.06877.x
The retinoid-inducible serine carboxypeptidase 1 (Scpep1; formerly RISC) is a lysosomal matrix protein that was initially identified in a screen for genes induced by retinoic acid. Recently, it has been spotlighted by several proteome analyses of the lyso[r]

Molecular targeted therapy has emerged as a promising treatment of Hepatocellular carcinoma (HCC). One potential target is the Src family Kinase (SFK). C-Src, a non-receptor tyrosine kinase is a critical link of multiple signal pathways that regulate proliferation, invasion, survival, metastasis, an[r]

RNA interference (RNAi) is an important molecular tool for analysis of gene function in vivo. Daphnia, a freshwater microcrustacean, is an emerging model organism for studying cellular and molecular processes involved in aging, development, and ecotoxicology especially in the context of environmenta[r]

ERM, PEA3 and ER81 belong to the PEA3 group of ETS tran- scription factors family, which share a common DNA-binding domain(ETS domain) of about 85 residues binding the consensus core sequence 5’-GGAA/T-3’. The PEA3 group members are often over-expressed in different types of<[r]

The broad excitation, narrow emission peak wavelengths of individual quantum dots, and availability of a wide range of quantum dots with different emission peaks allow for simultaneous imaging of multiple targets with multiple quantum nanoparticles. Taking advantag[r]

Chapter 114. Molecular Mechanisms of Microbial Pathogenesis
(Part 9)
Fungal pathogens almost always take advantage of host immunocompromise to spread hematogenously to deeper tissues. The AIDS epidemic has resoundingly illustrated this principl[r]

In addition to the abovementioned PI3K signalling pathway, other factors are related to the activation/inhibition of caspase-3. Indeed, the intracellular levels of calcium have a role in proteolysis not only by activating the calpain-dependent system (specific c[r]

The heterogeneity of cells across tissue types represents a major challenge for studying biological mechanisms as well as for therapeutic targeting of distinct tissues. Computational prediction of tissue-specific gene regulatory networks may provide important insights into the mechanisms underlying[r]

Berberine (BBR), a natural alkaloid compound, is used as a non-prescription drug in China for treating diarrhea and gastroenteritis. Many studies have revealed that BBR possesses anticancer effect. However, the molecular mechanisms underlying its anticancer action is far from being fully elucidated.

Hepatocellular carcinoma (HCC) is the leading cause of cancer mortality. Chemical and virus induction are two major risk factors, however, the potential molecular mechanisms of their differences remain elusive.

adverse prognosis if they express high levels of p170PGP, and modulation of this protein's function has been attempted by a variety of strategies.
Chemotherapeutic agents where drugs acting by different mechanisms were combined (e.g., an alkylating agent[r]

Lymphovascular invasion (LOI), a key pathological feature of head and neck squamous cell carcinoma (HNSCC), is predictive of poor survival; however, the associated clinical characteristics and underlying molecular mechanisms remain largely unknown.

Despite the current knowledge on the composition of wasp venoms, little is known about the participation of its components, and even the whole venom, on the AKI observed in envenomed patients. On the other hand, the mechanisms of bee venom-induced AKI have been[r]