IN GROUP 1 THE FETUS IS INFECTED BUT SHOWS NO CLINICAL MANIFESTATIONS AT BIRTH THOSE IN GROUP 2 ARE...

More than 50% of newborns with congenital heart disease (CHD) are unrecognized at birth; however, the use of echocardiogram (Echo) for diagnosing CHD in newborns with asymptomatic, non-syndromic cardiac murmurs (ANCM), has not been systematically reviewed yet.

Triple-negative breast cancer (TNBC) shows aggressive clinical behavior, but the treatment options are limited due to lack of a specific target. TNBC shares many clinical and pathological similarities with BRCA-deficient breast cancer, for which poly(ADP-ribose) polymerase (PARP) inhibitor is effect[r]

_HISTOPATHOLOGY AND IMMUNOPATHOLOGY IN MICE INFECTED _ _WITH LACV 100 LD50_ To further characterize the LACV infection in weanling mice, an additional group was inoculated intraperito-ne[r]

In contrast with breast cancers (BCs) in other parts of the world, most previous studies reported that the majority of BCs in sub-Saharan Africa are estrogen-receptor (ER) negative. However, a recent study using the US SEER database showed that the proportion of ER-negative BC is comparable between[r]

Multiple myeloma is an incurable cancer with a rising incidence globally. Less toxic treatments are increasingly available, so patients are living longer and treatment decisions are increasingly guided by QOL concerns. There is no QOL assessment tool designed specifically for use in the clinical car[r]

The impact of such recommendations after their implementation of guidelines has not usually been evaluated. Herein, we assessed the impact and compliance with the Spanish Oncology Genitourinary Group (SOGUG) Guidelines for toxicity management of targeted therapies in metastatic renal cell carcinoma[r]

Dubin-Johnson syndrome (DJS) is an autosomal recessive disorder presenting as isolated direct hyperbilirubinemia.DJS is rarely diagnosed in the neonatal period. The purpose of this study was to clarify the clinical features of neonatal DJS and to analyze the genetic mutation of adenosine triphosphat[r]

Oxaliplatin + S-1 is a recognized treatment regimen in Japan, but there are no Japanese clinical data on an oxaliplatin dose of 130 mg/m2. The current research involves a single-arm, prospective, phase II clinical trial to examine the efficacy and safety of oxaliplatin + S-1 with an oxaliplatin dose[r]

Autoimmune endocrine disorders are considered one of the extrahepatic manifestations of Hepatitis C virus (HCV) infection. HCV could trigger cytokines release due to local inflammation. Interleukin 17 a (IL17a) and Interferon gamma (IFNγ) play an important role in pathogenesis of autoimmune disease.[r]

Methadone is well known for its long duration of action and propensity for mortality after an overdose. The present research was aimed at evaluating the clinical manifestations and time trends of methadone exposure in patients in US hospitals.

Although international comparisons reveal large geographical differences in the incidence of breast and gynaecological cancers, incidence data for ethnic groups in England remains scarce. Our study provides evidence that the risk of breast and gynaecological cancers varies by ethnic group and that t[r]

The occurrence of multiple endocrine neoplasia type 2B (MEN2B) in Asians is very rare. In particular, patients with intractable constipation as the main clinical manifestation are even rarer. Atypical clinical manifestations are likely to lead to a diagnostic delay.

The poor psychological adjustment PARENTING STRESS IN MOTHERS OF CHILDREN WITH CONGENITAL HEART DISEASE _SUNHEE LEE_ _1_ _*, _ _RN_ _, _ _MSN_ _, JI-SOO YOO_ _2_ _, _ _RN_ _, _ _PhD_ _, [r]

In 1993, Greene and Krantz [14] posed a conjecture that for a smoothly bounded pseudoconvex domain admitting a non-compact automorphism group, the point orbits can accumulate only at a p[r]

Congenital central hypoventilation syndrome (CCHS) is a rare disease characterized by sleep apnea. Anoxia often occurs soon after birth, and it is important to prevent anoxia-mediated central nervous system complications; however, data on the relationship between respiratory management and the progn[r]

Central nervous system tumours constitute 25% of all childhood cancers; more than half are located in the posterior fossa and surgery is usually part of therapy. One of the most disabling late effects of posterior fossa tumour surgery is the cerebellar mutism syndrome (CMS) which has been reported i[r]

Paraneoplastic neurological syndrome (PNS) is a heterogeneous group of disorders affecting any part of the nervous system, in a patient affected by cancer. PNS is estimated to occur in 0.01 to 8 % of cancer patients, with higher incidence in those with small cell lung cancer, gynecological tumours o[r]

Relapse in localized Ewing sarcoma patients has been a matter of concern regarding poor prognosis. Therefore, we investigated the impact of local control modality (surgery, surgery plus radiotherapy, and radiotherapy) on clinical outcomes such as survival and recurrence in patients with non-metastat[r]

Testing for HIV at birth has the potential to identify infants infected in utero, and allows for the possibility
of beginning treatment immediately after birth; point of care (POC) testing allows rapid return of results and faster
initiation on treatment for positive infants. Eswatini piloted birth[r]

TRANG 1 BIOMEDCentral REPRODUCTIVE HEALTH OPEN ACCESS CASE REPORT MONOCHORIONIC TRIAMNIOTIC TRIPLET PREGNANCY WITH A CO-TRIPLET FETUS DISCORDANT FOR CONGENITAL CYSTIC ADENOMATOID MALFORM[r]