BÁO CÁO KHOA HỌC: " A SPECIFIC INHIBITOR OF PROTEIN KINASE CK2 DELAYS GAMMA-H2AX FOCI REMOVAL AND REDUCES CLONOGENIC SURVIVAL OF IRRADIATED MAMMALIAN CELLS" POT
Tìm thấy 10,000 tài liệu liên quan tới tiêu đề "Báo cáo khoa học: " A specific inhibitor of protein kinase CK2 delays gamma-H2Ax foci removal and re...":
BÁO CÁO KHOA HỌC: " A SPECIFIC INHIBITOR OF PROTEIN KINASE CK2 DELAYS GAMMA-H2AX FOCI REMOVAL AND REDUCES CLONOGENIC SURVIVAL OF IRRADIATED MAMMALIAN CELLS" POT
RESEARC H Open AccessA specific inhibitor of protein kinase CK2 delaysgamma-H2Ax foci removal and reducesclonogenic survival of irradiated mammalian cellsFelix Zwicker1,2*, Maren Ebert1, Peter E Huber1,2, Jürg[r]
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BÁO CÁO KHOA HỌC: SOLUTION STRUCTURE OF ISTX A MALE SCORPION TOXIN FROMOPISTHACANTHUS MADAGASCARIENSIS(ISCHNURIDAE) POT
443–450.4. Blanc, E ., Romi-Lebrun, R., Bornet, O ., Nakajima, T. & Darbo n,H. ( 1998) Solution structure of two n ew toxins fro m the veno m ofthe chinese scorpion Buthus martensi karsch blockers of thepotassium channels. Biochemistry 37, 12412–12418.5. Dai, L., Yasuda, A
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BÁO CÁO KHOA HỌC: ALTERED EXPRESSION OF TUMOR PROTEIN D52 REGULATES APOPTOSIS AND MIGRATION OF PROSTATE CANCER CELLS POTX
TPD52 +LY, 294,002Collagen-1050100150% Age of controlEGFPTPD52ABCDFig. 5. Overexpression of TPD52 stimulates cell migration. LNCaP cells transiently transfected with EGFP-TPD52 or EGFP as a control wereanalysed by haptotactic cell migration toward vitronectin (A) <[r]
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BÁO CÁO KHOA HỌC: HOW A LIPID MEDIATES TUMOUR SUPPRESSION DELIVERED ON 29 JUNE 2010 AT THE 35TH FEBS CONGRESS IN GOTHENBURG, SWEDEN PDF
mitogenic receptors. The second involves regulation of cytokinesis, which isthe final stage of cell division. Further elucidation of the mechanisms oftumour suppression mediated by class III PI3K and PtdIns3P will identifynovel Achilles’ heels of the cell’s defence[r]
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BÁO CÁO KHOA HỌC: IDENTIFICATION AND EXPRESSION OF THE FIRST NONMAMMALIAN AMYLOID-B PRECURSOR-LIKE PROTEIN APLP2 IN THE AMPHIBIAN XENOPUS LAEVIS PPT
¨dhof, T.C. (2001) A transcriptionally [correction oftranscriptively] active complex of APP with Fe65 and histoneacetyltransferase Tip60. Science 293, 115–120.37. Scheinfeld, M.H., Ghersi, E., Laky, K., Fowlkes, B.J. &D’Adamio, L. (2002) Processing of beta-amyloid[r]
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TÀI LIỆU BÁO CÁO KHOA HỌC REGULATION OF CONNECTIVE TISSUE GROWTH FACTOR CTGF CCN2 GENE TRANSCRIPTION AND MRNA STABILITY IN SMOOTH MUSCLE CELLS INVOLVEMENT OF RHOA GTPASE AND P38 MAP KINASE AND SENSITIVITY TO ACTIN DYNAMICS DOCX
hampered by a lack o f adequate tools to evaluate not onlytotal cellular PtdIns, but also local c oncentrations within thecells. M eanwhile, u sing actin-binding drugs, we showed thatthe express ion of the CTGF/CCN2 gene can be modulatedby either actin polymerization or the avai[r]
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BÁO CÁO KHOA HỌC: CHARACTERIZATION OF A EUKARYOTIC TYPE SERINE/THREONINE PROTEIN KINASE AND PROTEIN PHOSPHATASE OF STREPTOCOCCUS PNEUMONIAE AND IDENTIFICATION OF KINASE SUBSTRATES DOC
phenotypes of many of the single knockouts are relat-ively weak and the function of particular proteinkinase cannot be clearly assigned. Streptococcuspneumoniae, with its one pair of protein kinase andphosphatase, provides a good model to study[r]
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BÁO CÁO Y HỌC: PROPERTIES OF THE NA+/H+ EXCHANGER PROTEIN DETERGENT-RESISTANT AGGREGATION AND MEMBRANE MICRODISTRIBUTION POTX
microdomains. J. Biol. Chem. 271, 9690–9697.12. Ricci, V., Galmiche, A., Doye, A., Necchi, V., Solcia, E. & Boquet,P. (2000) High cell sensitivity to Helicobacter pylori VacA toxindepends on a GPI-anchored protein and is not blocked byinhibition of the clat[r]
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BÁO CÁO HÓA HỌC COMPARISON OF THREE RAPAMYCIN DOSING SCHEDULES IN A J TSC2 MICE AND IMPROVED SURVIVAL WITH ANGIOGENESIS INHIBITOR OR ASPARAGINASE TREATMENT IN MICE WITH SUBCUTANEOUS TUBEROUS SCLEROSIS RELATED TUMORS DOCX
779) and interferon-gamma is more effective than single agents intreating a mouse model of tuberous sclerosis complex. GenesChromosomes Cancer 2006, 45(10):933-44.32. Franz DN, Leonard J, Tudor C, Chuck G, Care M, Sethuraman G,Dinopoulos A, Thomas G, Crone KR: Rapa[r]
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BÁO CÁO Y HỌC: THE EMERY–DREIFUSS MUSCULAR DYSTROPHY ASSOCIATED-PROTEIN EMERIN IS PHOSPHORYLATED ON SERINE 49 BY PROTEIN KINASE A PPTX
phorylation using a Xenopus egg mitotic cytosol model system (Hiranoet al. (2005) Dissociation of emerin from BAF is regulated through mitoticphosphorylation of emerin in a Xenopus egg cell-free system. J. Biol.Chem. 280, 39 925–39 933). In the present paper, recombinant[r]
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TÀI LIỆU BÁO CÁO KHOA HỌC: BACITRACIN IS NOT A SPECIFIC INHIBITOR OF PROTEIN DISULFIDE ISOMERASE PPTX
tein disulfide isomerase (PDI) in vivo. However, the specificity of action ofan inhibitor for a protein-folding catalyst cannot be determined in vivo.Furthermore, in vitro evidence for the specificity of bacitracin for PDI isscarce, and the mechanism of[r]
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BÁO CÁO KHOA HỌC: ERK AND CELL DEATH: ERK1⁄2 IN NEURONAL DEATH SRINIVASA SUBRAMANIAM1 AND KLAUS UNSICKER2 PPTX
In addition, a recent study suggested that sustainedERK1 ⁄ 2 recruits micro-RNA to promote PC12 cellsurvival by blocking the expression of the proapoptoticBH3-only protein Bcl2-interacting mediator of celldeath (BIM) [32]. Similarly, whether micro-RNA areinv[r]
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BÁO CÁO KHOA HỌC: THE STOP TRANSFER SEQUENCE OF THE HUMAN UDPGLUCURONOSYLTRANSFERASE 1A DETERMINES LOCALIZATION TO THE ENDOPLASMIC RETICULUM BY BOTH STATIC RETENTION AND RETRIEVAL MECHANISMS DOCX
teins contain a C-terminal stop transfer sequence with a transmembranedomain (TMD), which anchors the protein into the membrane, followedby a short cytosolic tail (CT). Here, we investigated the mechanism of ERresidency of UGT1A mediated by the stop transfer[r]
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TÀI LIỆU BÁO CÁO KHOA HỌC: NOVEL ASPECTS OF HEAT SHOCK FACTORS: DNA RECOGNITION, CHROMATIN MODULATION AND GENE EXPRESSION PPT
processes. Mammalian cells have four HSF family members involved in dif-ferent, but in some cases similar, biological functions, including stress resis-tance, cell differentiation and development. Mammalian HSF familymembers exhibit differential specificity for different t[r]
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BÁO CÁO KHOA HỌC: LIGHT REGULATION OF CAS, A NOVEL PHOSPHOPROTEIN IN THE THYLAKOID MEMBRANE OF ARABIDOPSIS THALIANA DOC
247–259.CaS – novel thylakoid phosphoprotein of Arabidopsis J. P. Vainonen et al.1776 FEBS Journal 275 (2008) 1767–1777 ª 2008 The Authors Journal compilation ª 2008 FEBS36 Palmgren MG, Askerlund P, Fredrikson K, Widell S,Sommarin M & Larsson C (1990) Sealed inside-out andright-side-o[r]
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BÁO CÁO KHOA HỌC: ERK AND CELL DEATH: CADMIUM TOXICITY, SUSTAINED ERK ACTIVATION AND CELL DEATH POT
treated with the phorbol ester 4b-phorbol 12-myristateERK and cell death: cadmium toxicity P. Martin and P. Pognonec42 FEBS Journal 277 (2010) 39–46 ª 2009 The Authors Journal compilation ª 2009 FEBS13-acetate (PMA), which activates conventional, aswell as novel, PKCs. PKCs play a
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BÁO CÁO HÓA HỌC: " RIFT VALLEY FEVER VIRUS STRUCTURAL PROTEINS: EXPRESSION, CHARACTERIZATION AND ASSEMBLY OF RECOMBINANT PROTEINS" POTX
under the control of the polyhedrin promoter was generated. Gel filtration analysis indicated thatexpressed N protein could form complex multimers. Further, N protein complex when visualizedby electron microscopy (EM) exhibited particulate, nucleocapsid like-particles (NLPs).Sub[r]
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BÁO CÁO HÓA HỌC: " HUMAN OLIGODENDROGLIAL CELLS EXPRESS LOW LEVELS OF C1 INHIBITOR AND MEMBRANE COFACTOR PROTEIN MRNAS" PPTX
Foster City, CA), 1.25 units AmpliTaq Gold DNApolymerase (Perkin Elmer), 2 mM MgCl2 (Perkin Elmer),200 µM dNTPs (Gibco BRL, Life Technologies) and 0.5µM of each specific primer (Table 1). The mixture was pre-pared before the addition of 1.25 µl of cDNA. PCR[r]
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BÁO CÁO KHOA HỌC: PURIFICATION AND STRUCTURAL STUDY OF THE B FORM OF HUMAN CAMP-DEPENDENT PROTEIN KINASE INHIBITOR PDF
4. Gamm, D.M. & Uhler, M.D. (1995) Isoform-specific differencesin the potencies of murine protein-kinase inhibitors are due tononconserved amino-terminal residues. J. Biol. Chem. 270, 7227–7232.5. Walsh,D.A.,Angelos,K.L.,VanPatten,S.M.,Glass,D.B.&Garetto, L.[r]
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BÁO CÁO KHOA HỌC TUMOR NECROSIS FACTOR RECEPTOR CROSS TALK DOCX
from the blood of type 1 diabetes patients, which didnot have an effect on other activated and memoryT-cell populations [21]. In summary, TNFR2 can playa vital role in the maintenance of the delicate and com-plex processes involved in immune system functioning.TNF[r]
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