URG4 OVEREXPRESSION IS CORRELATED WITH CERVICAL CANCER PROGRESSION AND POOR PROGNOSIS IN PATIENTS WITH EARLY-STAGE CERVICAL CANCER
Tìm thấy 10,000 tài liệu liên quan tới tiêu đề "URG4 overexpression is correlated with cervical cancer progression and poor prognosis in patients wi...":
URG4 OVEREXPRESSION IS CORRELATED WITH CERVICAL CANCER PROGRESSION AND POOR PROGNOSIS IN PATIENTS WITH EARLY-STAGE CERVICAL CANCER
Clinical evidence has indicated that URG4 is elevated in patients with certain types of cancer. Its expression has been shown to be associated with tumour aggressiveness in osteosarcomas, prostate cancer and neuroblastomas [11-13]. These[r]
11 Đọc thêm
APOPTOSIS INHIBITOR-5 OVEREXPRESSION IS ASSOCIATED WITH TUMOR PROGRESSION AND POOR PROGNOSIS IN PATIENTS WITH CERVICAL CANCER
The apoptosis inhibitor-5 (API5), anti-apoptosis protein, is considered a key molecule in the tumor progression and malignant phenotype of tumor cells. Here, we investigated API5 expression in cervical cancer, its clinical significance, and its relationship with phosphorylated extracellular signal-r[r]
12 Đọc thêm
A survey of physician receptivity to molecular diagnostic testing and readiness to act on results for early-stage colon cancer patients
physicians was less than 50 %. Therefore, survey responses may not be representative of physicians who care for pa- tients diagnosed with early-stage colon cancer. In addition, the survey was administered to physicians in one geo- graphic area; and,[r]
Knowledge, attitudes, and practices toward cervical cancer prevention among women in Kampong Speu Province, Cambodia
Methods
Study participants
A community-based cross-sectional KAP survey on cer- vical cancer prevention was conducted for women aged 20 – 69 years in Kampong Speu Province, Cambodia, between January 8 and February 19, 2016. Kampong Speu is a rural area located in
Study participants
A community-based cross-sectional KAP survey on cer- vical cancer prevention was conducted for women aged 20 – 69 years in Kampong Speu Province, Cambodia, between January 8 and February 19, 2016. Kampong Speu is a rural area located in
Both comorbidity and worse performance status are associated with poorer overall survival after external beam radiotherapy for prostate cancer
In this retrospective study, we evaluated the biochemical recurrence rate, metastatic disease progression, and prostate cancer-specific and overall survival in patients curatively treated with external beam radiotherapy (EBRT) for early prostate cancer (PC).
Pharmacokinetics and safety of cyclophosphamide and docetaxel in a hemodialysis patient with early stage breast cancer: A case report
Standardized chemotherapy used in cancer patients with severe kidney insufficiency is ineffective. Although there are some pharmacokinetic studies on cyclophosphamide in kidney insufficiency patients, to the best of our knowledge, the pharmacokinetics and safety of combination of cyclophosphamide an[r]
Health seeking behavior and its determinants for cervical cancer among women of childbearing age in Hossana Town, Hadiya zone, Southern Ethiopia: Community based cross sectional study
Cervical cancer is one of the most easily preventable forms of female cancers if early screening and diagnosis is made. Low awareness level about the disease and risk factors, beliefs about the disease, poor access to preventive services, affordability of the service and current health service syste[r]
OCCULT INVASIVE CERVICAL CANCER AFTER SIMPLE HYSTERECTOMY: A MULTI-CENTER RETROSPECTIVE STUDY OF 89 CASES
Occult invasive cervical cancer (OICC) is sometimes incidentally found in surgical specimens after a simple hysterectomy (SH). This study was aimed at identifying a subset of patients with OICC who have a favorable prognosis. This patient group may not require adjuvant radiotherapy and other procedu[r]
9 Đọc thêm
PROGNOSTIC SIGNIFICANCE OF ANNEXIN A2 AND ANNEXIN A4 EXPRESSION IN PATIENTS WITH CERVICAL CANCER
The annexins (ANXs) have diverse roles in tumor development and progression, however, their clinical significance in cervical cancer has not been elucidated. The present study was to investigate the clinical significance of annexin A2 (ANXA2) and annexin A4 (ANXA4) expression in cervical cancer.
SAFETY AND EFFICACY OF TEMSIROLIMUS AS SECOND LINE TREATMENT FOR PATIENTS WITH RECURRENT BLADDER CANCER
Bladder cancer is the 7th cause of death from cancer in men and 10th in women. Metastatic patients have a poor prognosis with a median overall survival of 14 months. Until recently, vinflunine was the only secondline chemotherapy available for patients who relapse.
9 Đọc thêm
IDENTIFICATION OF NOVEL CLASS OF TRIAZOLOTHIADIAZOLES AS POTENT INHIBITORS OF HUMAN HEPARANASE AND THEIR ANTICANCER ACTIVITY
Expression and activity of heparanase, an endoglycosidase that cleaves heparan sulfate (HS) side chains of proteoglycans, is associated with progression and poor prognosis of many cancers which makes it an attractive drug target in cancer therapeutics.
INFLUENCE OF MTOR-INHIBITORS AND MYCOPHENOLIC ACID ON HUMAN CHOLANGIOCELLULAR CARCINOMA AND CANCER ASSOCIATED FIBROBLASTS
The incidence of Cholangiocellular Carcinoma (CCA) is increasing in the western world. The tumour has a high proportion of desmoplastic stroma and is correlated with a worse prognosis when cancer associated myofibroblasts (CAFs) are present. Recent studies showed promising results after liver transp[r]
SOX2 expression is associated with a cancer stem cell state and down-regulation of CDX2 in colorectal cancer
similar to other reports in CRC [25 – 27]. In our study,
the prognostic importance of CDX2 remained significant in multivariable analyses adjusted for stage and other confounders, suggesting that CDX2 is a powerful prog- nostic factor in CRC. When c[r]
the prognostic importance of CDX2 remained significant in multivariable analyses adjusted for stage and other confounders, suggesting that CDX2 is a powerful prog- nostic factor in CRC. When c[r]
BÁO CÁO HÓA HỌC TRIP BR2 PROMOTES ONCOGENESIS IN NUDE MICE AND IS FREQUENTLY OVEREXPRESSED IN MULTIPLE HUMAN TUMORS PPT
carcinoma cells was performed to determine the potential of TRIP-Br2 as a novel chemotherapeutic drug target.Results: Overexpression of TRIP-Br2 is sufficient to transform murine fibroblasts and promotes tumorigenesis in nudemice. The transformed phenotype is chara[r]
15 Đọc thêm
PREDICTION OF LYMPH NODE METASTASIS BY TUMOR-INFILTRATING LYMPHOCYTES IN T1 BREAST CANCER
Lymph node metastasis is more likely in early-stage breast cancer with lower tumor-infiltrating lymphocyte (TIL) density. Therefore, we investigated the correlation between TILs and lymph node metastasis in cT1 breast cancer patients undergoing surgery and the usefulness of TILs in predicting sentin[r]
IDENTIFYING A LOW-RISK GROUP FOR PARAMETRIAL INVOLVEMENT IN MICROSCOPIC STAGE IB1 CERVICAL CANCER USING CRITERIA FROM ONGOING STUDIES AND A NEW MRI CRITERION
There are currently three ongoing studies on less radical surgery in cervical cancer: ConCerv, GOG-278, and SHAPE. The aim of this study was to evaluate the performance of the criteria used in ongoing studies retrospectively and suggest a new, simplified criterion in microscopic Stage IB1 cervical c[r]
FIBULIN-4 IS ASSOCIATED WITH TUMOR PROGRESSION AND A POOR PROGNOSIS IN OVARIAN CARCINOMAS
Fibulin-4, a member of the fibulin family of extracellular glycoproteins, is implicated in the progressions of some cancers. However, no information has been available to date regarding the function of fibulin-4 in ovarian carcinoma progression.
BENEFIT OF ADJUVANT CHEMOTHERAPY IN PATIENTS WITH T4 UICC II COLON CANCER
Colorectal cancer is the third most common cancer and a major cause of morbidity and mortality worldwide. Adjuvant chemotherapy is considered the standard of care in patients with UICC stage III colon cancer after R0 resection.
RISK ALLELIC LOAD IN TH2 AND TH3 CYTOKINES GENES AS BIOMARKER OF SUSCEPTIBILITY TO HPV-16 POSITIVE CERVICAL CANCER: A CASE CONTROL STUDY
Alterations in the host cellular immune response allow persistent infections with High-Risk Human Papillomavirus (HR-HPV) and development of premalignant cervical lesions and cervical cancer (CC). Variations of immunosuppressive cytokine levels in cervix are associated with the natural history of CC[r]
STOMATIN-LIKE PROTEIN 2 IS OVEREXPRESSED IN EPITHELIAL OVARIAN CANCER AND PREDICTS POOR PATIENT SURVIVAL
Stomatin-like protein 2 (SLP-2, also known as STOML2) is a stomatin homologue of uncertain function. SLP-2 overexpression has been suggested to be associated with cancer progression, resulting in adverse clinical outcomes in patients. Our study aim to investigate SLP-2 expression in epithelial ovari[r]