and found similar trends. Thus, in this paper we present results that include all self-reported cases of type 2 DM. We excluded women from the current Int. J. Med. Sci. 2006, 3 154analysis who had diabetes or had a positive urinary glucose test at the baseline survey. The total follow-up was[r]
of wild type BRCA1 and BRCA2, DSBs can be efficiently repaired by RAD51 mediated homologous recombination (Fig. 1B). It has been shown that BRCA1 and BRCA2 interact with RAD51, and play essential role in homologous recombination [28, 30, 31]. Thus, in the event of DNA damage associated with PARP inh[r]
. The PCR was con-ducted with initial denaturation at 95°C for 10 minutes, 30 cycles of denaturation at 95°C for 1 minute, an-nealing at 60°C for 1 minute, and extension at 72°C for 1 minute, and a final extension at 72°C for 5 minutes. The primers were F1: 5’-AGC CTC TCC TGA CTG TCA TCC-3’,[r]
Figure 1 shows the hierarchical gene expression profile of 1 mM ethanol concentration treated HepG2 cells (group 1) and control cells (HepG2 cells without treatment; group 2) exposed for a 6 h period. Data are presented as a median of the signal obtained from the six different microarr[r]
Cirrhosis), is a multicenter study of the potential benefit of prolonged peginterferon therapy in mitigating the progression of fibrotic liver disease. [8] In this study, 391 of the 1045 patients enrolled into the initial “lead-in” phase had biopsy proven cirrhosis. Preliminary results show t[r]
1) Why to Treat HCV Infection The treatment of HCV is justified by the natural history and the outcome of chronic infection and liver injury that is associated with cirrhosis, hepatic decompensation, development of HCC, and mortality. In addition, HCV infection has been linked to a variety of[r]
pregnancy. 3. Results In the repeated analysis of the first period (up to and including 2001) we restricted births to those occurring Int. J. Med. Sci. 2006, 3 107after July 1, 1995 and searched the registers for all known cases of hypospadias. The total number of loratadine-exposed infants is then[r]
12. Stuyver L, et al. Hepatitis C virus genotyping by means of 5'-UR/core line probe assays and molecular analysis of untypeable samples. Virus Res 1995, 38: 137-57. 13. Zheng X, et al. Direct comparison of hepatitis C virus genotypes tested by INNO-LiPA HCV II and TRUGENE HCV genotyping methods. J[r]
Kevin Robertson5, Robert Paul6, Cecilia Shikuma1, Victor Valcour1 1. Hawaii AIDS Clinical Research Program, University of Hawaii, Honolulu, HI, USA; 2. Armed Forces Research Inst. Med. Sciences, Bangkok, Thailand; 3. Phramongkutklao Hosp., Bangkok, Thailand; 4. Royal Thai Army Med. Dept., Bangkok, T[r]
Trepo C, et al. Analysis of HCV co-infection with occult hepatitis B virus in patients undergoing IFN therapy. J Clin Virol 2005;33:150-157. 49. Villa E, Grottola A, Buttafoco P, Colantoni A, Bagni A, Ferretti I, Cremonini C, et al. High doses of alpha-interferon are required in[r]
27. Apichartpiyakul C, Apichartpiyakul N, Urwijitaroon Y, Gray J, Natpratan C, Katayama Y, Fujii M, Hotta H. Seroprevalence and subtype distribution of hepatitis C virus among blood donors and intravenous drug users in northern/ northeastern Thailand. Jpn J Infect Dis 1999;52:121–123 28. Songsivilai[r]
4. Serfaty L, Aumaitre H, Chazouilleres O, Bonnand AM, Rosmorduc O, Poupon RE, et al. Determinants of outcome of compensated hepatitis C virus-related cirrhosis. Hepatology 1998;27:1435-1440. 5. Kasahara A, Hayashi N, Mochizuki K, Takayanagi M, Yoshioka K, Kakumu S, Iijima A, Urushihar[r]
and severity of disease. Am J Gastroenterol 2001; 96:2957. 10. Pagano G, Pacini G, Musso G, et al. Nonalcoholic steatohepatitis, insulin resistance, and metabolic syndrome: Further evidence for an etiologic association. Hepatology 2002; 35:367. 11. Marchesini G, Brizi M, Morselli-Labate AM, et al. A[r]
tion. Exercise is a known stress condition that con-sumes muscle glycogen rapidly. During the recovery period following exercise, the whole-body glucose tolerance and the rate of muscle glycogen storage in-creases simultaneously, resulting in glycogen super-compensation [5]. This normal adapt[r]
Exon 1 (transcript variant 3) and exon 10 were amplified from selected samples with PCR parameters as described above. After a control electrophoresis on 2% agarose gels, the PCR products were directly subjected to processing with Surveyor nuclease [13] (Transgenomic, Omaha, USA) according to[r]
QuantiTect SYBR green RT-PCR kit (Qiagen, Hilden, Germany). Specific primers for transcription factor (AP1, SRF, Elk1, Stat1 and NFκB) and members of the Fas receptor signaling pathway (Fas receptor, Fas Int. J. Med. Sci. 2006, 3 162ligand, FADD and caspase 8) were used. Primer design was performed[r]
association between hepatitis C infection and survival after orthotopic liver transplantation. Gastroenterology 2002;122:889-96. 10. Berenguer M, Prieto M, San Juan F, Rayon JM, Martinez F, Carrasco D, Moya A, Orbis F, Mir J, Berenguer J. Contribution of donor age to the recent decrease in pa[r]
mitogen-activated protein kinase activation in response to lysophosphatidic acid and epidermal growth factor. J Biol Chem 2000; 275: 13842 – 8. 14. Ymazaki S, Nishida K, Yoshida Y, et al. Gab1 is required for EGF receptor signaling and the transformation by activated ErbB2. Oncogene 2003; 22: 1546-5[r]