BÁO CÁO Y HỌC: "A COMPARATIVE ANALYSIS OF EXOME CAPTURE" POTX

1) Why to Treat HCV Infection The treatment of HCV is justified by the natural history and the outcome of chronic infection and liver injury that is associated with cirrhosis, hepatic decompensation, development of HCC, and mortality. In addition, HCV infection has been linked to a variety of[r]

tion. Exercise is a known stress condition that con-sumes muscle glycogen rapidly. During the recovery period following exercise, the whole-body glucose tolerance and the rate of muscle glycogen storage in-creases simultaneously, resulting in glycogen super-compensation [5]. This normal adapt[r]

group relegated to the same caloric-restricted diet as the Test group. Many published studies concerning methods to combat obesity provide only scale weight loss as the principal end point. The assumption that scale weight loss is synonymous with fat loss, however, is not al-ways true [26,27]. Scale[r]

Cirrhosis), is a multicenter study of the potential benefit of prolonged peginterferon therapy in mitigating the progression of fibrotic liver disease. [8] In this study, 391 of the 1045 patients enrolled into the initial “lead-in” phase had biopsy proven cirrhosis. Preliminary results show t[r]

Germany). HDL was measured following precipitation of apoB containing lipoproteins with phosphotungstate (Boehringer Mannheim). Apoliprotein AI (Apo AI) and Apo B were measured using the Beckmann Array 360 (Beckmann Instruments). Genotyping DNA was extracted from white blood cells using standard met[r]

Cirrhosis), is a multicenter study of the potential benefit of prolonged peginterferon therapy in mitigating the progression of fibrotic liver disease. [8] In this study, 391 of the 1045 patients enrolled into the initial “lead-in” phase had biopsy proven cirrhosis. Preliminary results show t[r]

association between hepatitis C infection and survival after orthotopic liver transplantation. Gastroenterology 2002;122:889-96. 10. Berenguer M, Prieto M, San Juan F, Rayon JM, Martinez F, Carrasco D, Moya A, Orbis F, Mir J, Berenguer J. Contribution of donor age to the recent decrease in pa[r]

QuantiTect SYBR green RT-PCR kit (Qiagen, Hilden, Germany). Specific primers for transcription factor (AP1, SRF, Elk1, Stat1 and NFκB) and members of the Fas receptor signaling pathway (Fas receptor, Fas Int. J. Med. Sci. 2006, 3 162ligand, FADD and caspase 8) were used. Primer design was performed[r]

Trepo C, et al. Analysis of HCV co-infection with occult hepatitis B virus in patients undergoing IFN therapy. J Clin Virol 2005;33:150-157. 49. Villa E, Grottola A, Buttafoco P, Colantoni A, Bagni A, Ferretti I, Cremonini C, et al. High doses of alpha-interferon are required in[r]

antiviral therapy. 2. VIROLOGICAL TOOLS Serological assays Anti-HCV antibody detection The detection of anti-HCV antibodies in plasma or serum is based on the use of third-generation EIAs, that detect mixtures of antibodies directed against various HCV epitopes. Recombinant antigens are used to capt[r]

and severity of disease. Am J Gastroenterol 2001; 96:2957. 10. Pagano G, Pacini G, Musso G, et al. Nonalcoholic steatohepatitis, insulin resistance, and metabolic syndrome: Further evidence for an etiologic association. Hepatology 2002; 35:367. 11. Marchesini G, Brizi M, Morselli-Labate AM, et al. A[r]

Int. J. Med. Sci. 2006, 3 148International Journal of Medical Sciences ISSN 1449-1907 www.medsci.org 2006 3(4):148-151 ©2006 Ivyspring International Publisher. All rights reserved Short Research Communication Mutation Analysis of hCDC4 in AML Cells Identifies a New Intronic Polymorphism Dani[r]

Received: 2006.07.07; Accepted: 2006.10.25; Published: 2006.10.27 Aim: To investigate the association between meat intake and incidence of type 2 diabetes (type 2 DM) in a large cohort of middle-aged women. Design, subjects and methods: Incident cases of type 2 DM were identified during an av[r]

association between hepatitis C infection and survival after orthotopic liver transplantation. Gastroenterology 2002;122:889-96. 10. Berenguer M, Prieto M, San Juan F, Rayon JM, Martinez F, Carrasco D, Moya A, Orbis F, Mir J, Berenguer J. Contribution of donor age to the recent decrease in pa[r]

the MTT assay. The results showed that hESC survivability after exposure to 25oC and 4oC for 24h was 77.3 ± 4.8 % and 64.4 ± 4.4 % respectively (significantly different, P < 0.05). The corresponding survival rates after 48h exposure to 25oC and 4oC was 71.0 ± 0.5 % and 69.0 ± 2.3 % respective[r]

Synthesis Kit (Affymetrix). Fifteen micrograms of labeled and fragmented cRNA were subsequently hybridized to a Human Genome U133 plus 2.0 microarray (Affymetrix). After the hybridization, the DNA microarrays were washed and stained on a Fluidics Station (Affymetrix) according to manufacturer[r]

date the mechanism of this network. However, a poor correlation between mRNA and protein abundance has also been reported [9]. Furthermore, a single gene can encode for more than one mRNA species through differential splicing, and proteins can undergo as many as 200 posttranslational m[r]

. The PCR was con-ducted with initial denaturation at 95°C for 10 minutes, 30 cycles of denaturation at 95°C for 1 minute, an-nealing at 60°C for 1 minute, and extension at 72°C for 1 minute, and a final extension at 72°C for 5 minutes. The primers were F1: 5’-AGC CTC TCC TGA CTG TCA TCC-3’,[r]

from MedTex Company, Istanbul, Turkey. The chromatogram was developed with sodium phosphate and sodium azide buffers. Abnormal Hb was 20.0 % of the total Hb; HbA2; 2.0% and Hb A ;77.3% [6]. HbF value was determined by alkali denaturation method and found as 0.7 % [7]. The p50 values obtained[r]

95% confidence interval (CI) = 1.14 - 1.49). We found a protective effect of the XPA 23G/G genotype (OR = 0.75, 95% CI = 0.59 - 0.95). Considering the data available, it can be conjectured that if there is any risk association between a single SNP and lung cancer, the risk fluctuation[r]