BÁO CÁO KHOA HỌC: " HIGH-THROUGHPUT SEQUENCING IDENTIFIES STAT3 AS THE DNA-ASSOCIATED FACTOR FOR P53-NF-ΚB-COMPLEX-DEPENDENT GENE EXPRESSION IN HUMAN HEART FAILURE" PPS
Tìm thấy 10,000 tài liệu liên quan tới tiêu đề "báo cáo khoa học: " High-throughput sequencing identifies STAT3 as the DNA-associated factor for p53...":
BÁO CÁO KHOA HỌC: " HIGH-THROUGHPUT SEQUENCING IDENTIFIES STAT3 AS THE DNA-ASSOCIATED FACTOR FOR P53-NF-ΚB-COMPLEX-DEPENDENT GENE EXPRESSION IN HUMAN HEART FAILURE" PPS
25. Cummins EP, Berra E, Comerford KM, Ginouves A, Fitzgerald KT, Seeballuck F, Godson C, Nielsen JE, Moynagh P, Pouyssegur J, Taylor CT: Prolyl hydroxylase-1 negatively regulates IkappaB kinase-beta, giving insight into hypoxia-induced NFkappaB activity. Proc Natl Acad Sci USA 2006, 103:18154-18159[r]
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BÁO CÁO KHOA HỌC: INHIBITION OF THE NF-JB TRANSCRIPTIONAL ACTIVITY BY PROTEIN KINASE A POT
formed a complex with NF-jB, and overexpression ofC/EBPb inhibited the transactivation potential of p65,Gal4-p65 (1–551) and Gal4-p65 (286–551) (data notshown). A number of reports suggest a physiological roleof C/EBPb in mediating the PKA signaling. For instance,P[r]
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BÁO CÁO KHÓA HỌC NF JB AND C JUN DEPENDENT REGULATION OF HUMAN CYTOMEGALOVIRUS IMMEDIATE EARLY GENE PPT
34. Hacker, H., Vabulas, R.M., Takeuchi, O., Hoshino, K., Akira, S.& Wagner, H. (2000) Immune cell activation by bacterial CpG-DNA through myeloid differentiation marker 88 and tumornecrosis factor receptor-associated factor (TRAF)6. J. Exp. Med.192, 595–600.35. Chu, W.,[r]
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BÁO CÁO HÓA HỌC A PREDICTED PROTEIN KIAA0247 IS A CELL CYCLE MODULATOR IN COLORECTAL CANCER CELLS UNDER 5 FU TREATMENT DOC
24. Fingerle-Rowson G, Petrenko O: MIF coordinates the cell cycle with DNAdamage checkpoints. Lessons from knockout mouse models. Cell Div2007, 2:22.25. Yeh YH, Huang YF, Lin TY, Shieh SY: The cell cycle checkpoint kinaseCHK2 mediates DNA damage-induced stabilization of TTK/hMps1.Oncog[r]
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BÁO CÁO SINH HỌC A PREDICTED PROTEIN KIAA0247 IS A CELL CYCLE MODULATOR IN COLORECTAL CANCER CELLS UNDER 5 FU TREATMENT PPT
24. Fingerle-Rowson G, Petrenko O: MIF coordinates the cell cycle with DNAdamage checkpoints. Lessons from knockout mouse models. Cell Div2007, 2:22.25. Yeh YH, Huang YF, Lin TY, Shieh SY: The cell cycle checkpoint kinaseCHK2 mediates DNA damage-induced stabilization of TTK/hMps1.Oncog[r]
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TÀI LIỆU BÁO CÁO Y HỌC TRANSACTIVATION DOMAINS ARE NOT FUNCTIONALLY CONSERVED BETWEEN VERTEBRATE AND INVERTEBRATE SERUM RESPONSE FACTORS POTX
analyses of expression of human (Hs), D. melanogaster (Dm), A. franciscana (Af) and hybrid molecules (H/D, D/H, H/A, A/H, D/A, A/D) byWestern blot using anti-myc Ig. Ten micrograms of the cell extracts obtained in the transfection shown in (A) were analyzed.[r]
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TÀI LIỆU BÁO CÁO KHOA HỌC: CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF DESC1, A NEW MEMBER OF THE TYPE II TRANSMEMBRANE SERINE PROTEINASE FAMILY PPTX
towards soluble factors and away from the cell surfacemay be generally important for the function of mem-bers of this intriguing and emerging subfamily ofserine proteases.Experimental proceduresCloning, expression and purificationCloning, expression and purification[r]
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CHAPTER 080 CANCER CELL BIOLOGY AND ANGIOGENESIS PART 3
appropriate physiologic signals. Senescent cells have been identified in patients whose premalignant lesions harbor activated oncogenes, for instance, dysplastic nevi that encode an activated form of BRAF (see below), demonstrating that induction of senescence is a protective mechanism[r]
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BÁO CÁO KHOA HỌC SOX10 IN COMBINATION WITH SP1 REGULATES THE ENDOTHELIN RECEPTOR TYPE B GENE IN HUMAN MELANOCYTE LINEAGE CELLS PPTX
was also seen in normal human epidermal melano-cytes, and 624mel human melanoma cell lines exam-ined (Fig. 3B), and other human melanoma cell lines,G361 and SK-MEL-28 (data not shown). These resultssuggest that the potential SOX10 sites are dispensablefor me[r]
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BÁO CÁO KHOA HỌC: CONSTITUTIVE EXPRESSION OF THE HUMAN PEROXIREDOXIN V GENE CONTRIBUTES TO PROTECTION OF THE GENOME FROM OXIDATIVE DNA LESIONS AND TO SUPPRESSION OF TRANSCRIPTION OF NONCODING DNA PDF
quantitation of the population of SubG1 cells 24 hafter exposure to 50 lm menadione (Fig. 4C).8-OxoG was analysed in the KD-1 clone using aflow cytometric method based on the ability of 8-oxoGto bind avidin [27]. As a control, we used a stableclone of A549 cells obt[r]
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BÁO CÁO KHOA HỌC: ADVANCED GLYCATION END PRODUCTS AND LIPOPOLYSACCHARIDE SYNERGISTICALLY STIMULATE PROINFLAMMATORY CYTOKINE⁄CHEMOKINE PRODUCTION IN ENDOTHELIAL CELLS VIA ACTIVATION OF BOTH MITOGEN-ACTIVATED PROTEIN KINASES AND NUCLEAR FACTOR-JB PDF
81012***Fig. 3. AGE-HSA and LPS stimulate MAP kinase phosphorylation and NF-jB nuclear translocation. HUVECs were incubated with AGE-HSA(25 lgÆmL)1), LPS (10 ngÆmL)1), or their combination, for 30 min. (A). Total (upper panel) and phosphorylated (lower panel) p38, ERK1 ⁄ 2 andJNK were[r]
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BÁO CÁO HÓA HỌC:" CORRELATION BETWEEN EXPRESSION OF P53, P21/WAF1, AND MDM2 PROTEINS AND THEIR PROGNOSTIC SIGNIFICANCE IN PRIMARY HEPATOCELLULAR CARCINOMA" DOCX
murine double minute 2 (MDM2). The tumor suppressorgene p53 plays a key role in regulating the cell cycle andserves as a principal mediator of growth arrest, senes-cence, and apoptosis in response to a broad array of cellu-lar damage [3]. The p[r]
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CHAPTER 065. GENE THERAPY IN CLINICAL MEDICINE (PART 3) DOCX
Chapter 065. Gene Therapy in Clinical Medicine (Part 3) Long-Term Expression in Genetic Disease: In Vivo Gene Transfer with Recombinant Adeno-Associated Viral (AAV) Vectors Recombinant AAV vectors have emerged as attractive gene[r]
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TÀI LIỆU BÁO CÁO KHOA HỌC PRELIMINARY MOLECULAR CHARACTERIZATION AND CRYSTALLIZATION OF MITOCHONDRIAL RESPIRATORY COMPLEX II FROM PORCINE HEART PPT
RNeasy kit (Qiagen, Hilden,Germany), respectively.Purified total RNA was used to run a reverse transcrip-tion reaction to synthesize the complementary cDNA bythe AMV first-strand cDNA synthesis system (BBI, Tor-onto, Canada) against the reverse primers of four porcinecomplex II subunits.[r]
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BÁO CÁO KHOA HỌC TRANSCRIPTION TERMINATION AT THE MOUSE MITOCHONDRIAL H STRAND PROMOTER DISTAL SITE REQUIRES AN A T RICH SEQUENCE MOTIF AND SEQUENCE SPECIFIC DNA BINDING PROTEINS PPTX
MKCl eluted fractions, respectively. Lanes 6, same as lane 4, except that 20 lgÆmL)1pD-TERM (R) DNA was used as atemplate. Lanes 7–9, same as in lane 4, except that pD-TERM (F) DNA carrying various nucleotide replacements (Mut1, Mut2, and Mut3 asshown in Fig[r]
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BÁO CÁO KHOA HỌC: SUPPRESSION OF NADPH OXIDASE 2 SUBSTANTIALLY RESTORES GLUCOSE-INDUCED DYSFUNCTION OF PANCREATIC NIT-1 CELLS DOC
production in vivo, and how glucose up-regulates theexpression of NOX2 requires further investigation.It has been reported that NF-jB, p38MAPK andp53 are the key points relating to apoptosis [12]. Aninhibitor of p38MAPK was used to confirm its rolein apoptosis. The increased leve[r]
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BÁO CÁO KHOA HỌC: HUMAN DELTA-LACTOFERRIN IS A TRANSCRIPTION FACTOR THAT ENHANCES SKP1 (S-PHASE KINASE-ASSOCIATED PROTEIN) GENE EXPRESSION PDF
Delta-lactoferrin enhances Skp1 gene transcription C. Mariller et al.2046 FEBS Journal 274 (2007) 2038–2053 ª 2007 The Authors Journal compilation ª 2007 FEBSdistance between these two recognition elements andthe initiation start point is crucial in order to promotethe induction[r]
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BÁO CÁO KHOA HỌC: TWO DIFFERENT TYPES OF HEPCIDINS FROM THE JAPANESE FLOUNDER PARALICHTHYS OLIVACEUS PPT
due to incorrect folding although the other two syn-thesized hepcidin peptides have antimicrobial activi-tites, because we did not confirm the structure ofsynthesized peptides. These results suggest that at leastHep-JF2 acts as an antibacterial agent in Japaneseflounder.Tog[r]
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BÁO CÁO KHOA HỌC THE PROMYELOCYTIC LEUKEMIA ZINC FINGER PLZF GENE IS A NOVEL TRANSCRIPTIONAL TARGET OF THE CCAAT DISPLACEMENTPROTEIN CUX1 REPRESSOR PPT
E-mail: francois.boudreau@usherbrooke.ca(Received 2 June 2010, revised 11 August2010, accepted 16 August 2010)doi:10.1111/j.1742-4658.2010.07813.xThe CCAAT-Displacement-Protein (CUX1) can transcriptionally represssucrase–isomaltase gene expression, a specific product of enterocytes that[r]
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BÁO CÁO KHOA HỌC: IDENTIFICATION OF ALTERNATIVE PROMOTER USAGE FOR THE MATRIX GLA PROTEIN GENE EVIDENCE FOR DIFFERENTIAL EXPRESSION DURING EARLY DEVELOPMENT IN XENOPUS LAEVIS DOC
specific reverse primer (XlMGPR1; Table 1). All PCR frag-ments thus obtained were digested with XhoI and HindIII,and the resulting DNA fragments were gel purified andinserted into the promoterless pGL2 vector (Promega,Madison, WI, USA) previously digested with the sameenzymes. [r]
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