A CRYSTAL STRUCTURE OF CO L4 2 PF6 2

(Received 17 November 2007, revised 30 January 2008, accepted 6 February 2008) doi:10.1111/j.1742-4658.2008.06324.x
In this study, the crystal structure of a class C b -lactamase from a psychro- philic organism, Pseudomonas fluorescens , has been refined to 2.2 [r]

K D values for both steroids increased by over twofold in all the mutants with decreased hydrophobicity in the SEHC (i.e. W92A, L125A ⁄ V127A and W92A ⁄ L125A ⁄ V127A). Consistent with the increased K D values in those mutants, the K M values of 5-AND increased, indicating that the SEHC contr[r]

Constructively, the overall fold of AII in aqueous solution state is reminiscent of the conformation observed when AII is bound to the mAb Fab131. However, in the crystal structure of the complex, a hydrogen bond between the -NH 3 + terminal of Asp1 a[r]

ORTEP view of the two complexes CoL 3 and 1’(Co III ) as obtained by single crystal X-ray diffraction: (a) CoL 3 perspective view, (b) 1’(Co III ).. perspective view.[r]

1.5 STRUCTURAL LENGTH SCALES:
NANOSTRUCTURE, MICROSTRUCTURE, AND MACROSTRUCTURE
It should be clear from the above discussion that the structure of solids can be considered at different length scales (from atomic to microscopic and macroscopic scales). Physicists often work at the a[r]

stress imposed by extreme thermal motion. As a response, they have evolved enzymes that are highly stable against heat and other denaturants. The increased stability of enzymes from thermo- and hyper- thermophiles is considered to reflect structural rigidity, which in turn would accou[r]

Interactions characterized by exceedingly weak bind- ing affinities can be probed sensitively by NMR spectro- scopy. However, attempts to observe an interaction between E. coli DnaG-C and a shorter DnaB-N frag- ment containing the N-terminal 161 residues by NMR spectroscopy were unsuccessful [[r]

At the crystal contact of SaSTP, Ser155 also forms a hydrogen bond to the very same residue (Arg13),
which is responsible for binding the phosphoserine residue in vivo [11]. This interaction suggests that the crystal structure might mimic a product complex[r]

5
M Ở ĐẦ U
Trong vài ch ụ c n ă m tr ở l ạ i đ ây, nhi ề u nhà Hoá h ọ c trên Th ế gi ớ i đ ã quan tâm
đế n vi ệ c t ổ ng h ợ p và nghiên c ứ u c ấ u t ạ o, tính ch ấ t c ủ a các ph ứ c ch ấ t ch ứ a nh ữ ng ph ố i t ử có h ệ vòng ph ứ c t ạ p, ch ứ a nhi ề u nguyê[r]

3.2.3 ANALYTICAL GEL FILTRATION TRANG 4 3.3 RESULTS 3.3.1 THERMAL STABILITY AT DIFFERENT SALT CONCENTRATIONS To understand the relationship between the presence of salt and the thermal s[r]

However, by the sixth repeat the reduction in NlpI superhelical pitch has folded the protein back onto itself, while MalT continues in a more regular superhelix and in conse-quence lacks[r]

The proposed structure of these co-sputtered films was shown as Figure 2 .After co-sputtering process, the amorphous as-deposited NTO thin films were annealed in vacuum atmosphere.. It i[r]

1 Laboratory of Structural Biology and the MOE Laboratory of Protein Science, School of Life Science & Engineering, Tsinghua University, Beijing, China; 2 National Laboratory of Institute of Basic Medical Sciences, Peking Union Medical College and Chines[r]

H a and Pro9 H a in minor conformer 1 were observed, indicating that peptide linkages of Leu3–Pro4 in minor conformer 2 and Gly8–Pro9 in minor conformer 1 exhi- bit a cis configuration. Peptide SD thus exists in three isoforms due to cis–trans isomerization about[r]

The presence of multiphase crystal structure was showed a novel effect such as the double hysteresis loop, unusual piezoelectric properties, and the exchange bias [r]

9 . These m / z values correspond to that
expected for nondeamidated ( m / z 3106.455),mono-deami- dated (+ 1 Da),double-deamidated (+ 2 Da) and triple- deamidated (+ 3 Da) forms of the peptide. This conclusion is further supported by the existence of only one monoiso- topic p[r]

Results and Discussion
Overview of the structure
As shown in supplementary Fig. S1, the polypeptide chain of Bc ZBP folds into a single, compact a ⁄ b domain. The overall structure can be divided into two distinct structural motifs shown with different s[r]

38-43 Crystal Form TRANG 11  Quartz Crystal SiO2  Snow Flake Ice Crystal due to crystalline structure of H2O SOME FAMILIAR CRYSTAL FORMS TRANG 12 SILICA TETRAHEDRA  THE BUILDING BLOC[r]

These three structures, as well as the structure of the native cathepsin B (Figs 3 and 4), demonstrate that the occluding loop can adopt a variety of positions, with the moving part consisting of residues between E109 and D124. The extent of the occluding lo[r]

On the other hand, they harbor a cysteine residue in their active centers that is activated towards perform- ing a nucleophilic attack. This cysteine residue could easily react with AdoMet because the D G for the transfer of the methyl group from AdoMet to cysteine is of[r]