Sorghum [Sorghum bicolor (L). Moench] is the crop for human and animal consumption. Sorghum is produced in areas that are too hot, a minimum average temperature of 25°C is necessary to ensure maximum grain production. Sorghum [Sorghum bicolor (L). Moench] is the crop for human and animal consumption[r]
... present microbial antigens to T cells, thus initiating an appropriate immune response DCs can also affect the immune response by modulating either the amplitude or the type of the response (Schulz... Mtb is an intracellular pathogen, thus all TB vaccines aim to generate antigen-specific memory T[r]
Therapy targeted to the human epidermal growth factor receptor type 2 (HER2) is used in combination with cytotoxic therapy in treatment of HER2+ breast cancer. Trastuzumab, a monoclonal antibody that targets HER2, has been shown pre-clinically to induce vascular changes that can increase delivery of[r]
A major impediment in the treatment of ovarian cancer is the relapse of chemotherapy-resistant tumors, which occurs in approximately 25% of patients. A better understanding of the biological mechanisms underlying chemotherapy resistance will improve treatment efficacy through genetic testing and nov[r]
Cervical cancer is caused by high-risk Human Papillomavirus (hr-HPV) infection associated with cofactors that has been analyzed as predictors of the remission or persistence of cytological abnormalities remission or persistence.
In Brief: Generic Celecoxib The FDA has authorized two manufacturers (Teva, Mylan) to market generic formulations of celecoxib (Celebrex – Pfizer), the only COX-2 selective inhibitor remaining on the US market.... Extended-Release Oxycodone and Acetaminophen (Xartemis XR) The FDA has approved a f[r]
Hepatocellular carcinoma (HCC) is the leading cause of cancer-related deaths worldwide. The only drug currently approved for clinical use in the treatment of advanced HCC is sorafenib. However, many patients with HCC show reduced sensitivity to sorafenib during treatment.
1. Background: Lung cancer is one of the common cancers. The disease has the highest incidence and mortality among cancers, most commonly seen in the elderly especially over 60 years old. The majority of lung cancer is related to secondhand and passive smoking and has over[r]
Persistent infection with high-risk Human Papillomavirus (HPVs) is associated with the development of cervical cancer. The transforming capacity of these viruses relies on the cooperative action of the E6 and E7 viral oncoproteins.
dicine is an everchanging science. As new research and clinical experience broaden our knowledge, changes in treatment and drug therapy are required. The authors and the publisher of this work have checked with sources believed to be reliable in their efforts to provide information that is complete[r]
... this choice of initial phase, we recover the flat-top profile at the Fourier Plane exactly if the amplitude profile of the input beam matches the amplitude profile of the inverse FT of the flat-top... 2008] The first step of this algorithm is to produce the initial guess for the SLM phase modula[r]
To ensure the highest quality of human papillomavirus (HPV) testing in primary cervical cancer screening, novel HPV assays must be evaluated in accordance with the international guidelines.
10 May 2018Cancer is a major public health burden in both developed and developing countries. Plantderived agents are being used for the treatment of cancer. Plants such as herbs have beenused in folk medicine for centuries in most of
... according to their concentration gradient, thereby causing changes in their cytosolic concentration These changes trigger other cellular reactions that result in the message being transmitted along... resolution of the selectivity and regulation of individual ion channels The outside-out version[r]
... interaction for intracellular uptake after the nanocarriers reach the target site from blood circulation and extravasation There are advantages and drawbacks for each of this strategy that will... and Y Y Yang, “Advanced Materials for Co -Delivery of Drugs and Genes in Cancer Therapy,” Advanced[r]
The United States emerged from World War II as the world’s leader in research, after which we initiated an experiment in governmentfunded, civiliancontrolled military research. After 50 years, with the changes in pressures and goals of the Army in transformation and the military taking on multiple r[r]
was reported.85,86 A direct correlation between bacterial colonization and the hypoxic state of the wound was shown innumerous studies. Knighton et al.87,88 compared the woundextent after subcutaneous inoculation of bacteria in hypoxicwounds with woun[r]
Tumor recurrence and metastasis occur at a high rate in patients with colon cancer. Identification of effective strategies for the treatment of colon cancer is critical. Recently, poly (lactic-co-glycolic acid) (PLGA) has been shown to have potential as a broad therapeutic drug delivery system.
Breast cancer treatment is tailored to the specific cancer subtype. Often, systemic treatment is given prior to surgery. Chemotherapy induces significant endoplasmic reticulum (ER) stress-mediated cell death and upregulation of 78-kDa glucose-regulated protein (GRP78).