CABAZITAXEL A NOVEL TAXANE FOR THE TREATMENT OF ADVANCED CRPC

Hepatocellular carcinoma (HCC) is the leading cause of cancer-related deaths worldwide. The only drug currently approved for clinical use in the treatment of advanced HCC is sorafenib. However, many patients with HCC show reduced sensitivity to sorafenib during treatment.

Although docetaxel-based chemohormonal therapy (CHT) is one of the standard treatments for castration-resistant prostate cancer (CRPC), pertinent biomarkers and precise mechanisms involved in the resistance for CHT for CRPC remain unknown.

For the first time, the finitetime stabilization with guaranteed cost control for linear
autonomous timevarying delay systems with bounded controls is studied in this paper.
Based on the Lyapunov functional method and a generalized Jensen integral inequality,
novel sufficient conditions for designin[r]

Bezlotoxumab (Zinplava) for Prevention of Recurrent Clostridium difficile Infection
The FDA has approved the fully human monoclonal antibody bezlotoxumab (Zinplava – Merck) for use with antibacterial drug treatment to reduce recurrence of Clostridium difficile...
Nusinersen (Spinraza) for Spinal M[r]

Antiviral Drugs for Seasonal Influenza 2016-2017
Antiviral drugs can be used for prophylaxis and treatment of influenza. Frequently updated information on influenza activity, testing for influenza, and antiviral resistance is available from the...
Another Insulin Glargine (Basaglar) for Diabetes[r]

Drugs for Bipolar Disorder
Bipolar disorder is characterized by intermittent episodes of mania and/or depression. Even with maintenance treatment, recurrences of manic or (more frequently) depressive episodes are common....
Sofosbuvir/Velpatasvir (Epclusa) for Hepatitis C
The FDA has approved Epc[r]

... convergence and accuracy have been achieved through our method The MoM algorithm is next used to design and analyze novel bandpass filters Several miniaturization techniques for bandpass filter design. .. made of filter structures, there is a need to investigate miniaturization of the filters Fi[r]

... interaction for intracellular uptake after the nanocarriers reach the target site from blood circulation and extravasation There are advantages and drawbacks for each of this strategy that will... and Y Y Yang, “Advanced Materials for Co -Delivery of Drugs and Genes in Cancer Therapy,” Advanced[r]

Insulin Degludec (Tresiba) - A New Long-Acting Insulin for Diabetes
The FDA has approved insulin degludec (Tresiba – Novo Nordisk) for treatment of adults with type 1 or type 2 diabetes. Insulin degludec is the third long-acting human insulin analog to...
Drugs Past Their Expiration Date
Healthca[r]

Dapagliflozin (Farxiga) for Type 2 Diabetes
Dapagliflozin (dap" a gli fl oe'' zin; Farxiga – Bristol-Myers Squibb/AstraZeneca), an SGLT2 (sodium-glucose co-transporter 2) inhibitor, has been approved by the FDA for oral treatment...
Macitentan (Opsumit) for Pulmonary Arterial Hypertension
The FDA[r]

Two New GLP-1 Receptor Agonists for Diabetes
Two new injectable GLP-1 (glucagon-like peptide-1) receptor agonists, dulaglutide (Trulicity [trū li si tee] – Lilly) and albiglutide (Tanzeum [tan'' zee um] – GSK), have been...
A Combination of Ledipasvir and Sofosbuvir (Harvoni) for Hepatitis C
The[r]

... block for the design of Analog and mixed signal integrated circuit systems, particularly for the design of continuous-time Gm-C filters Over the pass few years, a few CMOS transconductor designs have... years: VHF CMOS Transconductor design and CMOS LNA design In the first part, a novel IC struc[r]

... and query processing and no use of DTDs or XML Schema 2.2 XML Twig Pattern Matching Algorithms Since XML twig pattern matching is widely considered as a core operation in XML queries processing, ... holistic XML twig pattern processing, including the reduction of intermediate results for twig qu[r]

8. It was a ________ achievement.a. worthy praise b. worthier praise c. praising worthy d. praiseworthy9. I always feel _________ when I am away from home.a. homesickb. gaudyc. worthyd. furious10. Food poisoning can cause _________.a. dieb. deadc. deathd. deathless11. The[r]

Light irrigation was done in polybagsimmediately after transplanting to settle downthe media. The transplanted plantlets werekept under shade in net house (50 % shade)for hardening, i.e., for establishment of theplantlets. The media in the polybags were kept[r]

... especially the design of novel chiral indium( III) complexes for catalytic enantioselective carbon- carbon bond formation and their application to the synthesis of bioactive molecules In this part of the... growth of indium metal chemistry, various indium( III) complexes have gained widespread a[r]

Neoadjuvant therapy plus oesophagectomy has been accepted as the standard treatment for patients with potentially curable locally advanced oesophageal cancer. No completed randomized controlled trial (RCT) has directly compared neoadjuvant chemotherapy and neoadjuvant chemoradiation in patients with[r]

Durlaza - A 24-Hour Extended-Release Aspirin
The FDA has approved Durlaza (New Haven Pharmaceuticals), a 24-hour extended-release (ER) aspirin formulation available only by prescription, for secondary prevention of myocardial...
Fluad - An Adjuvanted Seasonal Influenza Vaccine for Older Adults
Th[r]

Antimicrobial Prophylaxis for Surgery
Antimicrobial prophylaxis can decrease the incidence of postoperative surgical site infection after some procedures. Since the last Medical Letter article on this subject, consensus guidelines...
QuilliChew ER - Extended-Release Chewable Methylphenidate Tablet[r]

This book is the result of a sequence of two courses given in the School of Appliedand Engineering Physics at Cornell University. The intent of these courses has beento cover a number of intermediate and advanced topics in[r]