4 MECP2 THE ROLE OF METHYL BINDING DOMAIN PROTEINS IN EPIGENETICS AND AUTOIMMUNITY

than 10 micrograms of protein bou nd to polyvinyliden e difluorideor nitrocellulose membranes. Anal. Biochem. 201, 255–264.36. Kim, T.D., Paik, S.R., Yang, C.H. & Kim, J. (2000) Structuralchanges in alpha-synuclein affect its chaperone-like activityin vitro. Protein Sci. 9, 2489–[r]

-group of Met54 in CyPB andthat of Met49 in CyPA r eflects only the presence of sterichindrance in the case of the complex o f CyPB and thedistorted trans-form. On the other hand, we found thatthe different forms o[r]

FEHs seem to be present in all plants, including thosenot accumulating fructans at all. Unravelling thefunction of these ‘defective invertases’ (containing FEHside activity) is a hot topic in this research area.While fructans are degraded by FEHs, the cleavage ofSuc into[r]

such as VCP. Although there are few data concerningdirect protein–lipid interaction involving AAA-ATP-ases that would prove a common molecular functionof the ND, our results are largely consistent with pre-vious observations. The apparent association of PEX1and VCP with <[r]

... the split- ubiquitin system The main objective of this analysis is to demonstrate the feasibility of the split- ubiquitin system to detect interactions between human proteins inside human cells and... linker histone hH1 with the other core histone proteins, hH2A, hH2B, hH3 and hH4 have been anal[r]

Chapter 10Interactions of Bioactive Plant Metabolites:Synergism, Antagonism, and AdditivityJohn Boik, Ara Kirakosyan, Peter B. Kaufman, E. Mitchell Seymour,and Kevin SpelmanAbstract Drugs are commonly used in mixtures, also called cocktails, to treat dis-ease, particularl[r]

these projects make it possible to study in detail thelevel of evolutionary residue conservation in proteins,including estimates of statistical significance. In thepresent study, we have extracted protein sequence datafrom 21 chordate proteomes and map[r]

doi:10.1111/j.1742-4658.2011.08094.xThe RNA folding trajectory features numerous off-pathway folding traps,which represent conformations that are often equally as stable as the nativefunctional ones. Therefore, the conversion between these off-pathway struc-tures and the[r]

the protein with negatively charged membranes.AbbreviationsBAPTA-AM, 1,2-bis(o-aminophenoxy)ethane-N,N,N ¢,N ¢-tetraacetic acid-acetoxymethyl ester; CFP, cyan fluorescent protein; Chel, chelators;CHO, chinese hamster ovary; Cyt, cytosol; ECS, extracellular solution; FP, fluorescent protein; Gal[r]

transcription activator from R. rubrum, reveals a five-coordinate NO-heme. Biochemistry 39, 388–396.25 Taoka S &amp; Banerjee R (2001) Characterization of NObinding to human cystathionine b-synthase: possibleimplications of the effects of CO and NO binding