Osteosarcoma is a highly genetically unstable tumor with poor prognosis. We performed microarray-based comparative genomic hybridization (aCGH), transcriptome sequencing (RNA-seq), and pathway analysis to gain a systemic view of the pathway alterations of osteosarcoma.
may be seeing other specialists. The internist has an important role in educating patients about the indications, benefits, risks, and limitations of genetic testing in the management of a number of diverse diseases. This is a difficult task, as scien[r]
mRNA not only prevented SSAT induction by DENSPM,but also prevented apoptosis [95].As will be shown below, overexpression of SSAT intransgenic animals not only profoundly altered tissuepolyamine homeostasis, but likewise created a very complexphenotype affecting skin, fat depots, female ferti[r]
The nature and magnitude of genetic divergence was estimated in 35 genotypes of tomato using Mahalanobis D2 – statistics. The genetic material revealed considerable amount of diversity for all the characters investigated. All the genotypes were grouped into 4 clusters. Maximum number of genotypes wa[r]
4 Genetic Variation and Skeletal Muscle TraitsThe ultimate goal of linkage and genome-wide association studies is the identification of specific genes and gene variants with clinically relevant influences on skeletal muscle traits important to physical function. The
Molecular characterization is helpful in understanding the phylogenetic relationship among various germplasm to reveal the genetic diversity among the used parental genotypes. Among several efficient methods for revealing genetic variability within and among plant populations, one of the most widely[r]
Genetic testing for BRCA1 and BRCA2 has led to the accurate identification of individuals at higher risk of cancer and the development of new therapies. Approximately 10-20% of the genetic testing for BRCA1 and BRCA2 leads to the identification of variants of uncertain significance (VUS), with highe[r]
Genetic variability is the prime objective for crop improvement fraternity. Higher the amount of variation for a character greater will be the scope of its improvement through selection. Fifty six genotypes of greengram were evaluated in RBD for estimation of genetic variability, heritability, genet[r]
Pancreatic cancer is poorly characterized at genetic and non-genetic levels. The current study evaluates in a large cohort of patients the prognostic relevance of molecular subtypes and key transcription factors in pancreatic ductal adenocarcinoma (PDAC).
Each supply can carry 3 Stati: 2 = OK 1 = accepted with deviation 0 = rejected The number of points is calculated: Total of the Stati / max. possible status * 35 Price With each raw material the suppliers are arranged according to price. For a supplier the[r]
On the basis of a summary of the theoretical matters regarding financial management mechanism of the public universities; the research analyzes and clarifies the practical financial management mechanism of the public universities under Ministry of Finance; on the basis of the findings, the author re[r]
In adults, RT-PCR detected fabp10b transcripts in all tissues assayed. Bycontrast, fabp10a transcripts were detected only in adult liver, intestine andtestis. This differential tissue distribution of transcripts for the duplicatedfabp10 genes suggests considerable divergence of[r]
president in his/her official term was dismissed during this study; (iii) Thedrafting and promulgation of the macro-level documents of upper-level leaders ormanagement agencies is well-done, which ensure to create a legal framework foruniversity presidents to do leadership, mana[r]
cell-cycle control system, completely based on documenteddata [3]. They studied the signal wave generated by themodel, that goes through all the consecutive phases of thecell-cycle progression, and verified, by simulation, that al-most all the state transitions of t[r]
the variational coefficients, randomizing just the matrix coefficients of one transform,adding noise (-10 decibels, or numbers from [-0.1, 0.1]) to all the matrix coefficients,changing just the colors, and adding symmetry.When applying these three automatic operators,[r]
DNA’s Discovery and StructureHonors Objectives SOL.BIO.6f Today’s Objectives:TSW investigate and understand the common mechanisms of protein synthesis, including the structure of DNA and its discovery. Our Genetic CodeThe genetic code is a sequenc[r]
gastrointestinal dysfunction, and hair loss. Taken together, these approaches provide proof of principle for the pharmacologic manipulation of p53 function (mutant or wild-type) that could greatly enhance therapeutic efficacy while decreasing toxicity. Knowledge of the[r]
Recently, abiotic stress like salinity, drought and temperature are the severe problems to worldwide wheat production, mostly in arid and semiarid areas. A feasible solution is breeding for salt-tolerant cultivars of wheat, while the presence of genetic variation is a prerequisite for genetic improv[r]
VNU Journal of Science, Mathematics - Physics 24 (2008) 111-118On equations of motion, boundary conditions and conservedenergy-momentum of the rigid stringNguyen Suan Han*Department of Physics, College of Science, VNU, 334 Nguyen Trai, Thanh Xuan, Hanoi, Vie[r]