THREE YEAR RESULTS OF FIRST EVER RANDOMIZED CLINICAL TRIAL ON TREATMENT IN DUPUYTREN S DISEASE PERCU...

127 Thiboutot DM, Shalita AR, Yamauchi PS, Dawson C, Kerrouche N, Arsonnaud S, Kang S. Adapalene gel, 0.1%, as maintenance therapy for acne vulgaris: a randomized, controlled, investigator-blind follow-up of a recent combination study. Arch Dermatol. 2006;142:597-602. 12[r]

Tumor and germline genomics
Somatic with or without germline genomic results were available for 41 (73%) patients. The most commonly somatic gene mutations identified in the present study are similar to those identified in previously conducted, large genomic studies, and [r]

Discussing randomized clinical trials (RCTs) with cancer patients is one of the most challenging communication tasks a physician faces. Only two prior Communication Skills Trainings (CSTs) focused on RCTs in oncology have been reported. Their results demonstrated the need for further improvement.

a PSA recurrence is documented, or to wait until metastatic disease or symptoms of disease are manifest. Trials in support of early therapy have often been underpowered relative to the reported benefit or have been criticized on methodologic grounds. One [r]

Sintilimab blocks the interaction between programmed death-1 (PD-1) and its ligands. The safety and efficacy of sintilimab combined with oxaliplatin/capecitabine (CapeOx) as first-line treatment were evaluated in patients with gastric (G)/gastroesophageal junction (GEJ) adenocarcinoma in a phase Ib[r]

dL (425 nmol/L) at 8 AM and 15.2 μg/dL (419 nmol/L) at 8 PM. A low-dose dexamethasone suppression test reduced her serum cortisol levels from 23.45 μg/dL (647 nmol/L) to 0.29 μg/dL (8 nmol/L). However, MRI of the sella turcica showed a 0.5-cm mass at the left inferior adenohypophysis. Trans s[r]

Risk stratification and prognosis prediction of acute myeloid leukemia (AML) are largely dependent on pre-treatment information. However, post-treatment data also provides much useful information. In this retrospective study, we explored whether the level of blood count recovery before and after the[r]

In Japan, oxaliplatin + S-1 (SOX) (oxaliplatin dose: 100 mg/m 2
) and SP were compared in the G-SOX study, but SOX did not demonstrate non-inferiority in com- parison to SP [9]. A recent application sought approval of oxaliplatin based on data in th[r]

The primary clinical manifestation of skin field cancerization is the presence of actinic keratoses (AKs). Current treatments for AKs related to skin field cancerization include photodynamic therapy (PDT) and colchicine.

We report on the results of a phase II clinical trial of Panagen (tablet form of fragmented human DNA preparation) in breast cancer patients (placebo group n = 23, Panagen n = 57). Panagen was administered as an adjuvant leukoprotective agent in FAC and AC chemotherapy regimens.

+ Other imaging probes if any: UIV or MRI images appear renalhydronephrosis due to ureter pelvic junction obstruction.+ Increasing renal hydronephrosis: increased size of renal pelvis,reduced thickness of renal parenchyma and decreased renal functionson renal scintigraphy.4.3. Some [r]

weight-for-age, height-for-age and weight-for-height were measured at a baseline and every three to six months.Self-reported adherence was assessed by questionnaires for nine months.Results: Ninety HIV-1-infected children initiated HAART, and were followed for a median of 15 mon[r]

consolidated subsidiaries' (together, “SQUARE ENIX GROUP") plans, estimates, strategies and beliefs are forward-looking statements about the future performance of SQUARE ENIX GROUP. These statements are based on management's assumptions and beliefs in light of info[r]

Note: RT, radiation therapy; NR, not reported; UFT, tegafur and uracil. The role of adjuvant chemotherapy for stage IB disease is undefined. Subset analysis of all the randomized studies showed no benefit in patients with stage IB. In addition, one clinic[r]

of cases of hematogenous osteomyelitis in children and 25% of cases of vertebral osteomyelitis in adults. The presence of sepsis occasionally requires initiation of empirical therapy after blood samples alone have been obtained for culture. If[r]

Chapter 124. Sexually Transmitted Infections: Overview and Clinical Approach (Part 15) Pelvic Inflammatory Disease: Treatment The 2006 CDC guidelines recommend initiation of empirical treatment for PID in sexually active young women and other women at risk[r]

Alternative phase II endpoints employ a time-dependent measure such asprogression-free survival or time-to-progression. However, the natural history ofHCC is difficult to predict as demonstrated by the two recent sorafenib trials. Themedian survival in the control group of the Asian stu[r]

secondary to a large treatment effect of the toxin. Patients with acute anal fissures had a healing rate of 100% at 15 days as com-pared to 0% of the 3 patients who received placebo. All patients who were injected with the toxin showed a significant decrease in ana[r]

An experiment was carried out to study the effect of foliar application of micronutrients on nutrient content of gerbera under protected condition at the Center of Excellence on Protected Cultivation, Indira Gandhi Krishi Vishwavidyalaya, Raipur, Chhattisgarh, during the year 2015-16. The experiment[r]

Chapter 133. Tetanus (Part 4) Tetanus: Treatment General Measures The goals of therapy are to eliminate the source of toxin, neutralize unbound toxin, and prevent muscle spasms while monitoring the patient's condition and providing support—especially respiratory support—[r]