DELIBERATE CONTROL OF MUSCLE STEM CELLS AND MUSCLE REGENERATION IN THE AGED NICHE

During hypoxia systemic arterioles dilate, at least in part, by opening of K ATP channels in vascular smooth-muscle cells due to the hypoxia-induced reduction in ATP concentration. By contrast, in pulmonary vascul[r]

The deregulated alternative splicing of key glycolytic enzyme, Pyruvate Kinase muscle isoenzyme (PKM) is implicated in metabolic adaptation of cancer cells. The splicing switch from normal PKM1 to cancerspecific PKM2 isoform allows the cancer cells to meet their energy and biosynthetic demands, ther[r]

3-kinase (PtdIns 3-kinase) that acts either downstream or upstream of the MAP kinases.
To determine the role of these signaling molecules in CTGF / CCN2 expression, cells were pretreated for 30 min with Pd-098059 (20 l M ), SB-20856 (10 l M ), SP-600125[r]

Fast and accurate automatic segmentation of skeletal muscle cell image is crucial for the diagnosis of muscle related diseases, which extremely reduces the labor-intensive manual annotation. Recently, several methods have been presented for automatic muscle cell segmentation.

Sarcocystis species are considered as one of the most prevalent parasites of bovines. Sarcocysts occur either macroscopically or microscopically in the tissues of bovine intermediate hosts. Sarcocystosis being an occult infection, most of the time diagnosis in intermediate host by clinical symptoms[r]

Multipotential ability of bone marrow-derived cells has been clarified, and their involvement in repair and maintenance of various tissues has been reported. However, the role of bone marrow-derived cells in osteogenesis remains unknown. In the present study, bone marrow-derived cells during ectopic[r]

Type 2 diabetes mellitus is one of the common metabolic disorders that ultimately afflicts large number of individuals. Adrenomedullin (AM) is a potent vasodilator peptide; previous studies reported development of insulin resistance in aged AM deficient mice. In this study, we employed a gene delive[r]

In-stent restenosis (ISR) occurs due to proliferation and migration of smooth muscle cells from media to intima resulting in re-narrowing of the vessel lumen. This study aims to investigate changes in the three main KCa channels in response to stent implantation in porcine coronary arteries as their[r]

Cardiomyocyte and Heart Failure 163
as a stabilizing protein. Using ATP, the G-actin interacts with the myosin globular head leading to the crossbridge formation and sarcomere shorting. Tropomyosin lies on the side of actin for rigidity to thin[r]

mediated by a mechanism that is distinct from that used to stimulate GS.
The observation that SB-203580 suppresses Li-stimulated glucose uptake implies that Li stimulates the p38 MAP kinase pathway. The notion that Li activates this stress signalling pathway is not unprecedent[r]

1 SPLENIUS CAPITIS MUSCLE 2 Levator scapulae muscle 3 SERRATUS POSTERIOR SUPERIOR MUSCLE IN:Ventral branches of C8-T4 O: Spinous processes of C6-T2 I: Ribs II-V F: Elevates the ribs II-V[r]

Italy
1. Introduction
Bone tissue represents a specialized connective tissue, comprising metabolically active cells within a mineralized extracellular matrix, that are vital to the performance of its structural, mechanical and metabolic roles (Milat & Ng, 2009).[r]

2009 ; Short et al. 2003 ; Conley et al. 2000 a, b ; Harber et al. 2009 ) and a decrease in metabolically active muscle mass with a concomitant increase in metabolically inactive fat mass (Paffenbarger et al. 1970 ; Goodpaster et al. 2000, 2006 ; Short[r]

The relationship between muscle strength and cardiometabolic risk factors in youth, and the potential influence of vitamin D status on this relationship, is not well understood. This study examined associations between muscle strength and dyslipidemia, serum 25-hydroxyvitamin D [25(OH)D], and weight[r]

In conclusion, the data presented here comparing the three tropomyosins is compatible with previous reports that suggest there is no simple correlation between specific ‘domains’ of Tm and the overall stability of the molecule but there are long[r]

Migrating cancer stem cells
Metastasis is a very important feature of malignant tumors, accounting for 90% death of tumor patients [90]. Metastasis is a multi-step process that involves progressive growth, vascularization, invasion, detach- ment, embolization, survival[r]

Small and large coiled subcutaneous sweat glands are situated all over the body except beneath mucocutaneous surfaces, that is, the labia minora or vermilion border of the lips. Normally, the fluid secretion of small coiled (eccrine) sweat glands, wh[r]

Polyhydroxylsteroids or oxysterols are oxygenated derivatives of steroids and constitute a family of compounds with various biological activities. Especially, oxysterols have been shown to exhibit cytotoxicity in a number of cell lines, including smooth muscle cells, fibroblasts and vascular endothe[r]