RECOMBINATION VARIATIONS AND IMPLICATIONS IN GENETIC ASSOCIATION STUDIES

The present study therefore, was taken up to estimate the parameters of variability and character association in pea so that the desired targets are achieved.

Minor differences were observed between genotypic and phenotypic variance for all the characters in both the cases suggesting that role of the environment was less in phenotypic expression of the traits. It can be seen through high heritability values[r]

Prostate cancer is the second most frequently diagnosed cancer in men worldwide. Current treatments include surgery, androgen ablation and radiation. Introduction of more targeted therapies in prostate cancer, based on a detailed knowledge of the signalling pathways, aims to reduce side effects, lea[r]

Argonaute 2 (AGO2), a central component of RNA-induced silencing complex, plays critical roles in cancer. We examined whether the single nucleotide polymorphisms (SNPs) of AGO2 were related to the risk of nasopharyngeal carcinoma (NPC).

The aetiology of testicular cancer remains elusive. In this manuscript, we review the evidence regarding the association between cannabis use and testicular cancer development. Methods: In this systematic review and meta-analysis, we reviewed literature published between 1st January 1980 and 13th Ma[r]

A study was conducted to assess the induced genetic variability, interrelationship among yield components and their direct and indirect effect on yield. Thirty six genotypes of linseed (Linum usitatissimum L.) were evaluated in Randomized Complete Block Design with three replications. Substantial am[r]

A disintegrin and metalloprotease 8 (ADAM8) has been reported to be associated with various malignancies. However, no studies have examined ADAM8 association in colorectal cancer (CRC). The aim of this study was to investigate the expression and function of ADAM8 in CRC.

Few studies have explored the association between social context and suicidal ideation using multilevel models. This study examines how suicidal ideation in adolescence is related to school class composition.

Studies of human polyomavirus (HPyV) infection and lung cancer are limited and those regarding the association of human papillomavirus (HPV) infection and lung cancer have produced inconsistent results.

The experiment “studies on collection and evaluation of genetic variability available in Amaranthus under Chhattisgarh plain condition” was conducted at Horticulture Research cum Instructional Farm, Department of Horticulture, Indira Gandhi Krishi Vishwavidyalaya, Raipur (C.G.) during Rabi 2014-15.[r]

Previous studies have shown left-sided colorectal cancer (LCRC) and right-sided colorectal cancer (RCRC) exhibit different molecular and clinicopathological features. We explored the association between the primary tumor site and cetuximab efficacy in KRAS wild-type colorectal cancer (CRC).

The aetiology of urological cancers is poorly understood and variations in incidence by ethnic group may provide insights into the relative importance of genetic and environmental risk factors. Our objective was to compare the incidence of four urological cancers (kidney, bladder, prostate and testi[r]

The present investigation was carried out in 25 sweet corn inbred lines during Rabi 2019-20. Significant differences among genotypes for most of the traits were noticed, indicating the presence of substantial genetic variability. Phenotypic coefficients of variation (PCV) were higher than genotypic[r]

7. Arcaroli J, Fessler MB, Abraham E: Genetic polymorphisms and sepsis. Shock 2005, 24:300-312.8. Beutler B: Innate immunity: an overview. Mol Immunol 2004, 40:845-859.9. Akira S, Uematsu S, Takeuchi O: Pathogen recognition and innate immunity. Cell 2006, 124:783-801.10. Fitzger[r]

Despite many prospective and retrospective studies about the association of dietary habit and lung cancer, the topic still remains controversial. So, this study aims to investigate the association of lung cancer with dietary factors.

Correlation studies revealed that the genotypic correlations were higher than their corresponding phenotypic correlation for all the characters and the depended trait pod yield per plant was significantly and positively correlated at both phenotypic and genotypic levels with number of mature pods pe[r]

Although genome-wide association studies (GWAS) have identified variants in approximately 40 susceptibility loci for colorectal cancer (CRC), there are few studies on the interactions between identified single-nucleotide polymorphisms (SNPs) and lifestyle risk factors.

In the present investigation 50 rice genotypes were used to study character association, path analysis and variability. The studies of variance among 50 genotypes for ten characters revealed that the genotypes differed significantly for all the characters under study.

Polymorphisms in the CYP1A2 genes have the potential to affect the individual capacity to convert pre-carcinogens into carcinogens. With these comprehensive meta-analyses, we aimed to provide a quantitative assessment of the association between the published genetic association studies on CYP1A2 sin[r]

Alcohol consumption is associated with higher breast cancer risk. While studies suggest a modest association between alcohol intake and mammographic density, few studies have examined the association in racial/ethnic minority populations.