GENE THERAPY FOR CANCER

Sensitive and reliable molecular diagnostics is needed to guide therapeutic decisions for cancer patients. Although less material becomes available for testing, genetic markers are rapidly expanding. Simultaneous detection of predictive markers, including mutations, gene amplifications and MSI, will[r]

.. .DELIVERY OF PROAPOPTOTIC BIOMOLECULES AND DRUGS USING AMPHIPHILIC BLOCK COPOLYMER NANOPARTICLES FOR ANTI- CANCER THERAPY ASHLYNN LINGZHI LEE (B.Eng (Chemical), Hons., NUS) A THESIS SUBMITTED FOR. .. fabricated and used for the codelivery of various anti- cancer drugs and therapeutic proteins for[r]

Liệu pháp gene (gene therapy) là một kĩ thuật sử dụng gene để ngăn ngừa và điều trị bệnh tật. Trong tương lai, kĩ thuật này có thể cho phép bác sỹ điều trị bệnh bằng cách chèn gene vào trong tế bào của bệnh nhân thay vì dùng thuốc hay phẫu thuật. Các nhà nghiên cứu đang thử nghiệm một số hướng đi đố[r]

(BQ) Part 2 book Nelson’s pediatric antimicrobial therapy presentation of content: Preferred therapy for specific parasitic pathogens, alphabetic listing of antimicrobials, antibiotic therapy for obese children, antibiotic therapy for patients with renal failure, adverse reactions to antimicrobial a[r]

A RNA sequencing dataset (the training set) and a microarray dataset (the validation set) were obtained from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) database, respectively. Differentially expressed genes (DEGs) between metastatic and non-metastatic OS samples were identified[r]

The prognostic significance of TP53 concurrent mutations in patients with epidermal growth factor receptor (EGFR)- or anaplastic lymphoma kinase (ALK)- mutated advanced non–small-cell lung cancer (NSCLC) who received EGFR-tyrosine kinase inhibitors (TKIs) or ALK-TKIs based targeted therapy remains c[r]

Previously, we have shown that miR-18a and miR-18b gene expression strongly correlates with high proliferation, oestrogen receptor -negativity (ER− ), cytokeratin 5/6 positivity and basal-like features of breast cancer.

làm gì? Sữa chữa gen bệnh Thay thế gen bệnh bằng gen lành Ức chế sự biểu hiện của gen bệnh Tiêu diệt tế bào bệnhPhân loại LPG:Nguyên tắc cơ bản của điều trị bằng LPG:Theo dõi và hiểu biết cặn kẽ quá trình, cơ chế phát sinh bệnh, đặctính di truyền của bệnh.Nắm vững cấu trúc và chức năng của gen[r]

Although cancer-related fatigue (CRF) has gained increased attention in the past decade, therapy remains a challenge. Treatment programs are more likely to be effective if the needs and interests of the persons involved are well represented.

The gene encoding fibroblast growth factor receptor 1 (FGFR1) is emerging as a therapeutic and prognostic biomarker in various cancer types, including head and neck squamous cell carcinoma (SCC).

DOI:http://dx.doi.org/10.7314/APJCP.2014.15.22.9607BRCA1 Promoter Hypermethylation for Detection of Breast Cancer in Viet NamRESEARCH ARTICLEBRCA1 Promoter Hypermethylation Signature for EarlyDetection of Breast Cancer in the Vietnamese PopulationPhuong Kim Truong1, Thuan[r]

In this article, we aimed to characterize the diffuse gastric cancer cells with MRI and transcriptomic data. We hypothesized that gene expression pattern is associated with the phenotype of the cells and that the heterogeneous enhancement pattern and the high tumorigenicity of SNU484 can be modulate[r]

This study aimed to investigate the efficacy and safety of cytokine-induced killer (CIK)/dendritic cell combined with CIK (DC–CIK) cell therapy in advanced gastrointestinal cancer (GIC).

... interaction for intracellular uptake after the nanocarriers reach the target site from blood circulation and extravasation There are advantages and drawbacks for each of this strategy that will... and Y Y Yang, “Advanced Materials for Co -Delivery of Drugs and Genes in Cancer Therapy,” Advanced[r]

Therapy targeted to the human epidermal growth factor receptor type 2 (HER2) is used in combination with cytotoxic therapy in treatment of HER2+ breast cancer. Trastuzumab, a monoclonal antibody that targets HER2, has been shown pre-clinically to induce vascular changes that can increase delivery of[r]

Studies of the domestic cat have contributed to many scientific advances, including the present understanding of the mammalian cerebral cortex. A practical capability for cat transgenesis is needed to realize the distinctive potential of research on this neurobehaviorally complex, accessible species[r]

Neoadjuvant therapy plus oesophagectomy has been accepted as the standard treatment for patients with potentially curable locally advanced oesophageal cancer. No completed randomized controlled trial (RCT) has directly compared neoadjuvant chemotherapy and neoadjuvant chemoradiation in patients with[r]

Liệu pháp gen (Therapy gene)

Although docetaxel-based chemohormonal therapy (CHT) is one of the standard treatments for castration-resistant prostate cancer (CRPC), pertinent biomarkers and precise mechanisms involved in the resistance for CHT for CRPC remain unknown.