The objective of this study was to investigate the influence of molecular weight of kcarrageenan on its ice recrystallization inhibition (IRI) activity. To reduce the molecular weight, acid hydrolysis with 0.1 M trifluoroacetic acid (TFA) at 80 C or 0.1 M hydrochloric acid (HCl) at 60 C was perfor[r]
It has been suggested that the ability to form amy- loid-like structures, given appropriate conditions, is a general property of the polypeptide chain [10,11]. This ability not only has pathological consequences, but can be turned into good use as functional amyloid, serving as structural anc[r]
underlying molecular mechanisms of carcinogenesis. Syn- ergetic effects of viral infections, genetic alterations, and environmental factors are key factors driving the aberrant activity of a variety of genes and signal pathways during NPC patho[r]
Gene expression and repression in insects is regulated through epigenetic mechanisms i.e. DNA Methylation, Histone modification and Noncoding RNAs which influence the phenotypic modification. In recent days insects are used as models in studying epigenetics. RNA interference (RNAi), also known as RN[r]
122 1. Introduction Light-driven electron transport is nature's molecular strategy for converting solar radiant energy into chemical energy. The process of photosynthetic electron transport occurs in both prokaryotic organisms ~ green and purple bacte[r]
The related tumour suppressor proteins Deleted in Colorectal Cancer (DCC) and neogenin are absent or weakly expressed in many cancers, whereas their insertion into cells suppresses oncogenic behaviour. Serine proteases influence the initiation and progression of cancers although the mechanisms are u[r]
Understanding the underlying molecular mechanisms involved in the formation of cutaneous malignant melanoma is critical for improved diagnosis and treatment. Keratinocytic nuclear receptor Retinoid X Receptor α (RXRα) has a protective role against melanomagenesis and is involved in the regulation of[r]
(Received 25 May 2010, revised 6 August 2010, accepted 9 August 2010) doi:10.1111/j.1742-4658.2010.07811.x Larvae of an anhydrobiotic insect, Polypedilum vanderplanki , accumulate very large amounts of trehalose as a compatible solute on desiccation, but the molecular mec[r]
1.5 Beyond Classical Poly(Hydroxycarboxylic Acids) 15 There is the possibility to select the amino acid component to incorporate func- tional groups into the chain in a facile manner [67] . Poly(propylene fumarates) are a bulk eroding class of polyester which are syn- the[r]
Label-retaining cancer cells (LRCC) have been proposed as a model of slowly cycling cancer stem cells (CSC) which mediate resistance to chemotherapy, tumor recurrence, and metastasis. The molecular mechanisms of chemoresistance in LRCC remain to-date incompletely understood.
We previously reported that 3''-ethynylcytidine (ECyd, TAS-106), an RNA polymerases inhibitor, enhances the anti-tumor efficacy of platinum in several tumor types in both in vitro and in vivo tumor models. However, the molecular mechanisms underlying the ECyd-induced enhancement remain elusive.
Chemotherapy is an important therapeutic approach for non-small cell lung cancer (NSCLC). However, a successful long-term treatment can be prevented by the occurring of chemotherapy resistance frequently, and the molecular mechanisms of chemotherapy resistance in NSCLC remain unclear.
Lymphovascular invasion (LOI), a key pathological feature of head and neck squamous cell carcinoma (HNSCC), is predictive of poor survival; however, the associated clinical characteristics and underlying molecular mechanisms remain largely unknown.
Understanding some risk factors for lower extremity DVT in the first time in patients treated at the intensive care unit of the Bach Mai hospital and the Friendship hospital. Review the results of lower extremity DVT prevention by low molecular weight heparin (Enoxaparin) in the above patient groups[r]
The proliferating activity of a single leukemia stem cell and the molecular mechanisms for their quiescent property remain unknown, and also their prognostic value remains a matter of debate. Therefore, this study aimed to demonstrate the quiescence property and molecular signature of leukemia stem[r]
Hypericum japonicum Thunb. ex Murray is widely used as an herbal medicine for the treatment of hepatitis and tumours in China. However, the molecular mechanisms of its effects are unclear. Our previous research showed that extracts of H. japonicum can induce apoptosis in leukaemia cells.
TRANG 8 VII LIST OF TABLES TABLE.2-1 Punch parameters used in data analyses ---16 TABLE.3-1 Materials and properties ---31 TABLE.3-2 Properties of PMMA with different molecular weight --[r]
Little is known concerning the cellular and molecular mechanisms that sustain sperm within the SST lumen for prolonged periods of storage. These mechanisms likely involve the rever‐ sibl[r]
Quantification of molecular cell processes is important for prognostication and treatment individualization of head and neck cancer (HNC). However, individual tumor comparison can show discord in upregulation similarities when analyzing multiple biological mechanisms.
CRC is one of the most common malignancies worldwide, and its molecular mechanisms remain unclear. Elevated levels of BAG3 have been reported in various tumors. The present study aimed to explore the expression and function of BAG3 in CRC.