ROLE OF THE NICOTINIC ACETYLCHOLINE RECEPTORS GENETIC VARIABILITY IN KNOWLEDGE PREVENTION AND TREATM...

Nicotinic acetylcholine receptors (nAChRs) have been reported to be overexpressed in malignancies in humans and is associated with tumorigenesis and cell migration. In previous studies of gastric cancer, alpha7 nicotinic acetylcholine receptor (α7-nAChR) overexpression leads to epithelial-mesenchyma[r]

To begin with, we felt that it was crucial to take account of the existing, and very different, social contexts in each of the countries where the databases are being introduced: first of all (in 1998) the widely reported Health S[r]

Genetic variability and diversity play a major role in framing successful breeding programme. It is evident that genetically diverse parents are likely to produce high heterotic effects and yield desirable transgressive segregants. Keeping this in view, the present study was conducted to evaluate na[r]

6 Estonia
Ku¨lliki Korts
Introduction
The Estonian human Genome Project (EGP) was launched in 1999, with a far-reaching ambition to create a national genetic database comprising samples of virtually the whole population. Though the gene researchers h[r]

The improvement of any crop mainly depends upon the nature and magnitude of genetic variability present in the base population. The objective of this study was to assess the genetic diversity and relationship among the G. hirsutum genotypes using multivariate Mahalanobis D2 statistics. Forty G. hirs[r]

The Role of Rifamycins in Tuberculosis Treatment
Despite the complexity of these drug interactions, the key role of the rifamycins in the success of
tuberculosis treatment mandates that the d[r]

Nicotinic acetylcholine receptors
Nicotinic acetylcholine receptors, or nAChRs, are cholinergic receptors that
form ligand-gated ion channels in the plasma membranes of certain neurons and on th[r]

Cotton is a crop of prosperity having a profound influence on men and matter. The assessment of genetic variability is prerequisite for organization of breeding programmes in any crop. Experiment on estimation of genetic variability parameters in F2 population of cross a RHAP 24 × RHAP 15 was carrie[r]

The phenotypic and genotypic co-efficient of variability of root length in both stressed and control condition were high with high heritability and high genetic advance over mean indicat[r]

2. THE RELEVANCE OF HAYEK’S THEORY OF KNOWLEDGE FOR FINANCIAL MARKETS
Surprisingly, financial market theorists have hardly acknowledged Hayek’s theories of knowledge, including acquisition and dispersion of knowledge. They have preferre[r]

These methods have high absolute sensitivity and potential for au- tomation. HPV seroreactivity to a given type reflects mainly type- specific HPV infection (as measured by DNA detection), but also sig- nals past exposure to other types that may be serologically detected. Although HPV DNA t[r]

consequently improving plant growth and flowering in the same species (Boyd et al., 1994). Zinc hyperaccumulation can also have a deterrent role, as shown for insect
and slug herbivory in T. caerulescens by Pollard and Baker (1997).
The s[r]

The antitumor drug nilotinib has a large inter- and intra individual variability in pharmacokinetics. Adherence to treatment may substantially influence plasma levels and has been recognized as the most important determinant of treatment failure in chronic myeloid leukemia (CML).

In this report, we have addressed the role of AEA in regulating 1 VCAM-1 expression in brain endothelial cells infected with TMEV and the possible receptors involved by using antagonists[r]

One of the major controversies of contemporary medicine is created by an increased consumption of nicotine and growing evidence of its connection to cancer, which urges elucidation of the molecular mechanisms of oncogenic effects of inhaled nicotine.

Breast cancer (BC) is highly heterogeneous with ~ 60–70% of estrogen receptor positive BC patient’s response to anti-hormone therapy. Estrogen receptors (ERs) play an important role in breast cancer progression and treatment.

Information regarding genetic variation for drought attributes, their heritability and genetic advance coupled with association of different component traits among themselves and with grain yield are of immense help to breeder for selection of parents in hybridization programme. Phenotypic variation[r]

3-1. Single-cell cultivation chip system [2-10]
To understand the variability of cells having the same genetic information and to observe the adaptation proc- esses of cells, we need to compare the sister cells or the direct des[r]

Chapter 15 - The special senses (part c) provides knowledge of the chemical senses: taste and smell. This chapter focus describe the location, structure, and afferent pathways of taste and smell receptors, and explain how these receptors are activated.

Angiogenesis plays an essential role in tumor growth and metastasis, and is a major target in cancer therapy. VEGFR and PDGFR are key players involved in this process. The purpose of this study was to assess the incidence of genetic variants in these receptors and its potential clinical implications[r]