RNA INTERFERENCE AND THE REGULATION OF RENAL GENE EXPRESSION IN HYPOXIA

ciated diseases all over the world. An estimated 3% ofthe world’s populations, (more than 350 million people)are chronically infected by HCV, which is the maincause of liver fibrosis, cirrhosis and hepatocellular carci-noma (HCC) [1]. Like other RNA viruses, HCV po[r]

Page 4 of 7high degree of strain variation. The current treatment ofcare, Pegylated interferon a in combination with riba-virin is costly, has significant side effects and fails tocure about half of all infections [12,13]. Hence, there isa need to develop an[r]

dependent expression of sterol 14-demethylase (CYP51) inrat ovaries and its contribution to the production of a meio-sis-activating steroid. J Biochem 2001, 130:849-856.29. Byskov AG, Andersen CY, Nordholm L, Thogersen H, Guoliang X,Wassman O, Andersen JV, Guddal E[r]

Chapter 080. Cancer Cell Biology and Angiogenesis (Part 8) PI3K is a heterodimeric lipid kinase that catalyses the conversion of phosphatidylinositol bisphosphate (PIP2) to phosphatidylinositol trisphosphate (PIP3), which acts as a plasma membrane docking site for proteins that[r]

expression of individual members of t he 4CL gene family was assayed in soybean cell cultures after elicitor treatment. Soybean cell cultures weretreated as i n ( A) and harvested at t he t imes i ndicated. To tal RNA (20 lg each) fro m elici tor-trea[r]

and the accumulation of intracellular Cer, an apoptotic event. However,apoptosis was inhibited by activation of PPARb. Interestingly, activationof PPARb enhanced the mRNA expression of CerK and CerK activity.Furthermore, the cell surviva[r]

A RNA sequencing dataset (the training set) and a microarray dataset (the validation set) were obtained from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) database, respectively. Differentially expressed genes (DEGs) between metastatic and non-metastatic OS samples were identified[r]

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these libraries was studied using real-time PCR in gills and mantle at differ-ent time points over the course of the thermal stress. Differential geneexpression levels were much higher in gills than in the mantle, showing thatgills are more sen[r]