HUMAN DENDRITIC CELLS IN CANCER

... damaging and telomeretelomerase effects and hence the mechanism of action of TQ in breast cancer cells In addition, it is of interest to investigate the effects of TQ in normal breast epithelial cells. .. Black cumin seeds (left) and chemical structure of thymoquinone (right) 23 Figure 10 Growth[r]

... the split- ubiquitin system The main objective of this analysis is to demonstrate the feasibility of the split- ubiquitin system to detect interactions between human proteins inside human cells and... linker histone hH1 with the other core histone proteins, hH2A, hH2B, hH3 and hH4 have been anal[r]

Cervical cancer is caused by high-risk Human Papillomavirus (hr-HPV) infection associated with cofactors that has been analyzed as predictors of the remission or persistence of cytological abnormalities remission or persistence.

... types for developing in vitro models for predicting organ- specific toxicity Immortalized cell lines such as the standard murine fibroblast cell line NIH/3T3 are commonly used in toxicity testing... human 18 induced pluripotent stem cell (hiPSC)-derived HPTC-like cells for the development of in[r]

Persistent infection with high-risk Human Papillomavirus (HPVs) is associated with the development of cervical cancer. The transforming capacity of these viruses relies on the cooperative action of the E6 and E7 viral oncoproteins.

This study aimed to investigate the efficacy and safety of cytokine-induced killer (CIK)/dendritic cell combined with CIK (DC–CIK) cell therapy in advanced gastrointestinal cancer (GIC).

Therapy targeted to the human epidermal growth factor receptor type 2 (HER2) is used in combination with cytotoxic therapy in treatment of HER2+ breast cancer. Trastuzumab, a monoclonal antibody that targets HER2, has been shown pre-clinically to induce vascular changes that can increase delivery of[r]

Pancreatic ductal adenocarcinoma is a devastating disease with poor outcome, generally characterized by an excessive stroma component. The purpose of this study was to develop a simple and reproducible in vitro 3D assay employing the main constituents of pancreatic ductal adenocarcinoma, namely panc[r]

... 1 .3. 4 Other regulatory mechanisms 30 1 .3. 5 Apoptosis and cancer 30 1 .3. 6 TRAIL signaling pathway as potential therapeutic target 32 Objectives of the study Chapter Materials and Methods 33 34 ... accompanying p 53 up-regulation 51 3. 4 I3M causes Bid cleavage 55 3. 5 I3M induces Bax confor[r]

Sorghum [Sorghum bicolor (L). Moench] is the crop for human and animal consumption. Sorghum is produced in areas that are too hot, a minimum average temperature of 25°C is necessary to ensure maximum grain production. Sorghum [Sorghum bicolor (L). Moench] is the crop for human and animal consumption[r]

The competing endogenous RNA (ceRNA) networks of long non-coding RNAs (lncRNAs) and microRNAs (miRs) have aroused wide concerns. The study aims to investigate the roles of lncRNA DANCRassociated ceRNA network in the growth and behaviors of colon cancer (CC) cells.

On the basis of chemical and spectral analyses, the fucoidan fractions obtained were found to be the sulfated fucogalactans containing sulfate ester groups and uronic acid, and composed essentially of fucose and galactose, as well as a minor amount of other sugars. The polysaccharide fractions were[r]

5.1 Classifying Organisms (Life Science)
5.2 Cells to Systems (Life Science)
5.3 Human Body Systems (Life Science)
5.4 Plants (Life Science)
5.5 Interactions in Ecosystems (Life Science)
5.6 Changes in Ecosystems (Life Science)

5.7 Water on Earth (Earth Science)
5.8 Weather Patterns (Earth Science)[r]

In this article, we aimed to characterize the diffuse gastric cancer cells with MRI and transcriptomic data. We hypothesized that gene expression pattern is associated with the phenotype of the cells and that the heterogeneous enhancement pattern and the high tumorigenicity of SNU484 can be modulate[r]

To ensure the highest quality of human papillomavirus (HPV) testing in primary cervical cancer screening, novel HPV assays must be evaluated in accordance with the international guidelines.

... present microbial antigens to T cells, thus initiating an appropriate immune response DCs can also affect the immune response by modulating either the amplitude or the type of the response (Schulz... Mtb is an intracellular pathogen, thus all TB vaccines aim to generate antigen-specific memory T[r]

Cervical cancer mainly caused by human papilloma virus infection, is the leading cancer in Indian women and the second most common cancer in women worldwide. Almost 80% of cases occurred in developing countries. The objectives of the study were to assess the knowledge, attitude regarding cervical ca[r]

The enrichment of cancer stem cell-like cells (CSCs) has been considered to be responsible for tumor progression after an initial response to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (EGFR-TKIs) in patients with non-small cell lung adenocarcinoma (NSCLC/ADC). CSCs with ALDH[r]

Several physiological (fertilization, placentation, wound healing) and pathophysiological processes (infection with enveloped viruses, cancer) depend on cell fusion.

... EFFECTS OF SULFIDE- CONTAINING COMPOUNDS ON DEVELOPMENT OF ATHEROSCLEROSIS IN HUMAN UNDOTHELIAL CELLS AND HYPERLIPIDEMIC RABBITS WEN YA-DAN Master of Medicine, Soochow University... Effects of SPRC on ultrastructure of thoracic aorta of NZW rabbits 143 4.4.5 Effects of SPRC on oxidative stress[r]