THE EMERGING ROLE OF MICRORNAS IN ADULT STEM CELLS
Tìm thấy 10,000 tài liệu liên quan tới từ khóa "THE EMERGING ROLE OF MICRORNAS IN ADULT STEM CELLS":
IDENTIFICATION OF MICRORNA PROFILE SPECIFIC TO CANCER STEM-LIKE CELLS DIRECTLY ISOLATED FROM HUMAN LARYNX CANCER SPECIMENS
Emerging evidences proposed that microRNAs are associated with regulation of distinct physiopathological processes including development of normal stem cells and carcinogenesis. In this study we aimed to investigate microRNA profile of cancer stem-like cells (CSLCs) isolated form freshly resected la[r]
SALINOMYCIN INDUCES CELL DEATH AND DIFFERENTIATION IN HEAD AND NECK SQUAMOUS CELL CARCINOMA STEM CELLS DESPITE ACTIVATION OF EPITHELIAL-MESENCHYMAL TRANSITION AND AKT
Cancer stem cells (CSC) are believed to play a crucial role in cancer recurrence due to their resistance to conventional chemotherapy and capacity for self-renewal. Recent studies have reported that salinomycin, a livestock antibiotic, selectively targets breast cancer stem cells 100-fold more effec[r]
CHAPTER 068. HEMATOPOIETIC STEM CELLS (PART 3) PDF
able to change the size of the stem cell pool have little effect on more mature blood cells.
For example, the growth factor erythropoietin, which stimulates red blood cell production from more mature precursor cells[r]
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MiR-23b controls ALDH1A1 expression in cervical cancer stem cells
Cancer stem cells has been widely investigated due to its essential role in cancer progression and drug resistance. Here, we try to find a new therapeutic target for cervical cancer stem cells.
BÁO CÁO SINH HỌC: "THE ‘STEM CELL’ CONCEPT: IS IT HOLDING US BACK" PPTX
Both of these questions are surprisingly thorny. Consider the matter of potency: the usual definition is the ability to generate cells of other types, but there are two problems with this. First, there are clearly cells[r]
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THE ROLE OF MULTIPOTENT CANCER ASSOCIATED FIBROBLASTS IN HEPATOCARCINOGENESIS
The presence of tumor supporting cells in various cancer, including in hepatocellular carcinoma (HCC), has become an important target in the study of carcinogenesis. The cancer-associated fibroblast (CAF), one of the most important cellular components in the cancer stroma, might contribute to the pr[r]
Intestinal stem cells isolation and culture characteristics in vitro by morphometry and flow cytometry
Adult stem cells are crucial for maintaining proper function and repair of tissues. The epithelium of the adult mammalian intestine is a constant dialog with its underlying mesenchyme to direct progenitor proliferation, lineage commitment, terminal differentiation and ultimately cell death. The epit[r]
CHAPTER 067 APPLICATIONS OF STEM CELL BIOLOGY IN CLINICAL MEDICINE PART 2 PPS
Strategies for transplantation of stem cells. 1. Undifferentiated or partially differentiated stem cells may be injected directly in the target organ or intravenously. 2. Stem cells may be differentiated ex[r]
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MicroRNA-30a regulates cell proliferation and tumor growth of colorectal cancer by targeting CD73
MicroRNAs are non-coding RNAs which regulate a variety of cellular functions in the development of tumors. Among the numerous microRNAs, microRNA-30a (miR-30a) is thought to play an important role in the processes of various human tumors. In this study, we aimed to explore the role of miR-30a in the[r]
Placenta-derived mesenchymal stem cells reduce the interleukin-5 level experimentally in children with asthma
Mesenchymal stem cells (MSCs) have been investigated as a new treatment option for various diseases in recent years. However, the role of placenta-derived MSCs in children with asthma remains unclear.
Potential applications of stem cells in livestock production
Stem cells have properties of self-renewal and differentiation. Stem cells can be acquired from both embryo and adult body organs. They have also got the ability to differentiate (potency) and to take over the characteristics of any cell type in the body (Plasticity). Because of these efficient char[r]
MIR-200A INHIBITS EPITHELIAL-MESENCHYMAL TRANSITION OF PANCREATIC CANCER STEM CELL
MIR-200a and EMT markers expression in CSC of PANC-1
MiR-200 family is known as tumor suppressor and they are usually down-regulated in EMT in some cancer stem cells, such as in prostate cancer and breast cancer [22,23]. MiR-200/ZEB2 pathway in
MiR-200 family is known as tumor suppressor and they are usually down-regulated in EMT in some cancer stem cells, such as in prostate cancer and breast cancer [22,23]. MiR-200/ZEB2 pathway in
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TUMORIGENIC HYBRIDS BETWEEN MESENCHYMAL STEM CELLS AND GASTRIC CANCER CELLS ENHANCED CANCER PROLIFERATION, MIGRATION AND STEMNESS
Emerging evidence indicates that inappropriate cell-cell fusion might contribute to cancer progression. Similarly, mesenchymal stem cells (MSCs) can also fuse with other cells spontaneously and capable of adopting the phenotype of other cells. The aim of our study was to investigate the role of MSCs[r]
SPECIAL ROLE OF FOXP3 FOR THE SPECIFICALLY ALTERED MICRORNAS IN REGULATORY T CELLS OF HCC PATIENTS
It has been reported that alterations of miRNAs in CD4 + T cells and Tregs are correlated with certain acti- vation states and diseases [26-28]. Our array data found a group of differentially expressed miRNAs in Tregs from the murine HCC model. Interestingly[r]
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INVESTIGATION OF THE ROLE OF MICRORNAS IN SPINOCEREBELLAR ATAXIA TYPE 3
TRANG 6 vi ABBREVIATIONS 3’ UTR 3’ untranslated region 5’UTR 5’ untranslated region ALS amyotrophic lateral sclerosis AR androgen receptor ATP adenosine triphosphate ATXN1 ataxin 1 prote[r]
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IMMUNOHISTOCHEMICAL ANALYSIS OF CANCER STEM CELL MARKERS IN PANCREATIC ADENOCARCINOMA PATIENTS AFTER NEOADJUVANT CHEMORADIOTHERAPY
Cancer stem cells (CSCs) have been reported to play an important role in chemoradiation resistance. Although the association of CSC markers with clinicopathological outcomes after neoadjuvant chemoradiotherapy (NACRT) has been reported in various types of cancers, there have been no such reports for[r]
CHAPTER 067 APPLICATIONS OF STEM CELL BIOLOGY IN CLINICAL MEDICINE PART 1 PPT
Subsequent studies, however, revealed that the stem cells had fused with cells resident in the organs. Further studies will be necessary to determine whether transdifferentiation of MSCs or other stem cell populations occur[r]
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Potential importance of protease activated receptor (PAR)-1 expression in the tumor stroma of non-small-cell lung cancer
Protease activated receptor (PAR)-1 expression is increased in a variety of tumor cells. In preclinical models, tumor cell PAR-1 appeared to be involved in the regulation of lung tumor growth and metastasis; however the role of PAR-1 in the lung tumor microenvironment, which is emerging as a key com[r]
CHAPTER 108 HEMATOPOIETIC CELL TRANSPLANTATION PART 2
setting, transplantation of >2.5 x 10 6 CD34 cells per kilogram, a number easily collected in most circumstances, leads to rapid and sustained engraftment in virtually all cases. Compared to the use of autologous marrow,[r]
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Reprogramming factors remodel melanoma cell phenotype by changing stat3 expression
The limited availability of melanoma stem cells is a major challenge for therapeutic reagent screening and study of molecular mechanisms. It has been shown that induced expression of four stem cell factors (Oct4, Sox2, Klf4, and c-Myc) changes the phenotype of osteosarcoma and breast cancer cells to[r]