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22.6 Can Glucose Provide Electrons for Biosynthesis? 683turn activate some 800 molecules of phosphorylase. Each of these catalyzes the for-mation of many molecules of glucose-1-P.The Difference Between Epinephrine and Glucagon Although both epinephrineand glucagon exert glycogenolytic effects, they[r]

triglycerides, reduced serum high-density lipoprotein (HDL) cho-lesterol, insulin resistance, and obesity. The prevalence of theseconditions is increasing in the United States. By most estimates,more than 30% of Americans are obese, and rising obesity has con-tributed to an epidemic of type 2[r]

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1ATPADPACTIVE FIGURE 21.15 Photophosphorylation. Photoexcitation of the R. viridis RC leads toreduction of a quinone, Q, to form QH2. Oxidation of QH2by the cytochrome bc1complex leads to Hϩtrans-location for ATP synthesis by the R. viridis F1F0–ATP synthase. Test yourself on the concepts in[r]

what you have learned in this chapter. (Hint: The methyl group atC-3 effectively blocks hydroxylation and normal ␤-oxidation. Youmay wish to initiate breakdown in some other way.)4. Even though acetate units, such as those obtained from fatty acidoxidation, cannot be used for net synthesis of carboh[r]

Catabolism converges via the citric acid cycle tothree principal end products: water, carbon dioxide,and ammonia. Simple, smallend products ofcatabolismEndproductsCitric acidcycleCO2FIGURE 17.7 The three stages of catabolism.Stage 1: Proteins, polysaccharides, and lipids are brokendown into their co[r]

max1VmaxKmy-intercept =ANIMATED FIGURE 13.10 A Hanes–Woolf plot of [S]/v versus [S]. See this figure animatedat www.cengage.com/login.Enzymatic Activity Is Strongly Influenced by pHEnzyme–substrate recognition and the catalytic events that ensue are greatly de-pendent on pH. An enzyme possesse[r]

Berkeley17.4 What Experiments Can Be Used to Elucidate Metabolic Pathways? 527nature of the compound containing the atom. Transformations of substrates andmetabolic intermediates labeled with magnetic nuclei can be traced by followingchanges in NMR spectra. Furthermore, NMR spectroscopy is a noninva[r]

structures. Cerebrosides that contain one or more sialic acid (N-acetylneuraminicacid) moieties are called gangliosides. Several dozen gangliosides have been charac-terized, and the general form of the biosynthetic pathway is illustrated for the case of ganglioside GM2(Figure 24.26). Sugar units are[r]

PDK1ERKRasKinase 1Rsk1PKinase 2PI3KPPMultiple signaling inputsFIGURE 32.47 Integration of signaling pathways.Activation of a ribosomal serine/threonine kinaseknown as Rsk1 requires phosphorylation by two proteinkinases: a phosphoinositide-dependent kinase (PDK1)and a mitogen-activated protein kinase[r]

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Variables, Expressions, and Assignment Statements 11In C++, assignment statements can be used as expressions. When used as an expression,an assignment statement returns the value assigned to the variable. For example, considern = (m = 2);The subexpression (m = 2) both changes the value[r]

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872 Chapter 28 DNA Metabolism: Replication, Recombination, and Repairevents associated with cell growth and division in eukaryotic cells fall into a generalsequence having four distinct phases: M, G1, S, and G2(Figure 28.11). Eukaryoticcells have solved the problem of replicating their enormous geno[r]

FIGURE 31.2 Structure and function of DnaK: (a) Domain organization and structure of the Hsp70 family mem-ber, DnaK.The ribbon diagram on the lower left is the ATP-binding domain of the DnaK analog, bovine Hsc70;bound ADP is shown as a stick diagram (purple). The ribbon diagram on the[r]

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hydrolysis, with hydrolysis being tightly coupled to the transport event. Other energysources also drive active transport processes, including light energy and the energystored in ion gradients. The original ion gradient is said to arise from a primary activetransport process, and the transport that[r]