THERAPEUTIC IMPLICATION FOR PARKINSON S DISEASE AND OTHER MOTOR DISORDERS

RESEARC H Open AccessReduction of freezing of gait in Parkinson’sdisease by repetitive robot-assisted treadmilltraining: a pilot studyAlbert C Lo1,2,3*, Victoria C Chang2,4, Milena A Gianfrancesco1, Joseph H Friedman2,4, Tara S Patterson1,2,Douglas F Benedicto1AbstractBackground: Pa[r]

tumor antigen in breast cancer. Clin Cancer Res 7,3328–3335.J. C. Fitzgerald and H. Plun-Favreau Autosomal recessive genes in Parkinson’s diseaseFEBS Journal 275 (2008) 5758–5766 ª 2008 The Authors Journal compilation ª 2008 FEBS 576324 Zhang L, Shimoji M, Thomas B, Moore DJ, Yu[r]

was observed (improvement of 3% p = 0.032), and a trend in the Timed up and go test (improvement of 11%; p =0.07) was also seen. In addition, the training appeared to have a positive influence on psychosocial aspects of thedisease as assessed by the Parkinson’s disease[r]

To investigate the alterations in plasma concentration of dopamine in patients with Parkinson’s disease. Subjects and methods: Changes in plasma concentration of dopamine were analyzed to find its correlations and clinical features in 45 patients with Parkinson’s disease (PD group) and 40 healthy pe[r]

RESEARC H Open AccessHealth-Related Quality of Life in Parkinsondisease: Correlation between Health UtilitiesIndex III and Unified Parkinson’s Disease RatingScale (UPDRS) in U.S. male veteransGalit Kleiner-Fisman1*, Matthew B Stern2, David N Fisman3AbstractObjectiv[r]

Neuroscience, Mount Sinai School ofMedicine, New York, NY 10029, USAFax: +1 212 241 3869Tel: +1 212 241 3155E-mail: zhenyu.yue@mssm.edu(Received 30 May 2009, revised 30 July2009, accepted 18 August 2009)doi:10.1111/j.1742-4658.2009.07343.xThe recent discovery of the genetic causes for Park[r]

E, Sung WK, Tan L, Wong MC, Tan EK et al. (2005)Comprehensive evaluation of common genetic variationwithin LRRK2 reveals evidence for association withsporadic Parkinson’s disease. Hum Mol Genet 14, 3549–3556.33 Biskup S, Mueller JC, Sharma M, Lichtner P, ZimprichA,[r]

34. Robert-Offerman SR, Leers MP, van Suylen RJ, Nap M, Daemen MJ,Theunissen PH: Evaluation of the membrane attack complexof complement for the detection of a recent myocardial inf-arction in man. J Pathol 2000, 191:48-53.35. Xi G, Hua Y, Keep RF, Younger JG, Hoff JT: Brain edema afterintrace[r]

Bid, BH3 interacting domain death agonist; CHIP, carboxyl terminus of heat-shock protein-70-interacting protein; FADD, Fas-associatedprotein with death domain; HSP, heat-shock protein; JNK, c-Jun N-terminal kinase; LRRK2, leucine-rich repeat kinase 2; MAPK, mitogen-activated protein kinase; MAPKK, M[r]

To investigate the prevalence of non-motor symptoms (NMSs) using non-motor symptom scale (NMSS) in patients with Parkinson’s disease (PD).

ease. Neurology 2008;70:1916-1925. 8. Mirek E, Rudziñska M, Szczudlik A. The assessment of gait disorders in pa-tients with Parkinson’s disease using the three-dimensional motion analysis system Vicon®. Neurologia, Neurochirurgia Polska 2007;41:128-133. 9. Fahn S,[r]

Figure 55 Abnormal neckposture in a patient withspasmodic torticollisFigure 56 Mechanisms of actions ofvarious botulinum toxins (BTX). Ach,acetylcholine©2004 CRC Press LLCFigure 57 Dystonic postur-ing of the hand consequentto perinatal hypoxiaFigure 58 Dystonic postur-ing of the foot consequentto pe[r]

cortical firing patterns vary with their membrane poten-tial, and thalamic neurons might behave as oscillators oreven resonators [16]. The interaction between cation cur-rents and calcium conductance may generate oscillationsfrom 0.5 to 4 Hz. Animal studies in models of Parkinson