THERAPEUTIC EFFECTS OF LIPOIC ACID ON HYPERGLYCEMIA AND INSULIN RESISTANCE

356 D.A. Rivas and R.A. FieldingAnderson, T. & Kearney, J. T. (1982). Effects of three resistance training programs on muscular strength and absolute and relative endurance. Research Quarterly for Exercise Sport, 53, 1–7.Anderson, S. R., Gilge[r]

East, and that the very nature of the fermentation evolved over several millennia.ReferencesGuasch-Jané, M.R., M. Ibern-Gómez, C.Andrés-Lacueva, O. Jáuregui, and R.M. Lamuela-Raventós. 2004. Liquid chromatography with mass spectrometry in tandem mode applied for the identificati[r]

E2F1 is a unique member of the E2F family of proteins as it is involved in cell cycle progression and apoptosis induction in response to DNA damage through its cap- acity to activate p53/p73 death pathways [3,4]. A previ- ous study reported that deregulated E2F1 acts as a drivin[r]

Mechanisms influencing breast cancer (BC) development and recurrence include hyperglycemia, hyperinsulinemia, high insulin-like growth factor-1, high circulating estrogen, inflammation and impaired cellular differentiation/apoptosis. A lifestyle program that targets all the above mechanisms may be w[r]

panel) or fatty acid vehicle (1% dimethylsulfoxide) (upper panel) for 0 h (left panel) and 8 h (right panel). (A) Ab42wt (50 lM) incubated for0 h with 1% dimethylsulfoxide. (B) Ab42wt (50 lM) incubated for 8 h with 1% dimethylsulfoxide. (C) Ab42wt (50 lM) incubated for 0 h with50 lM DH[r]

Autophagy is a bulk catabolic process that modulates tumorigenesis, therapeutic resistance, and dormancy. The tumor suppressor ARHI (DIRAS3) is a potent inducer of autophagy and its expression results in necroptotic cell death in vitro and tumor dormancy in vivo.

Chronic myeloid leukaemia is in principle a treatable malignancy but drug resistance is lowering survival. Recent drug discoveries have opened up new options for drug combinations, which is a concept used in other areas for preventing drug resistance.

Mammalian target of rapamycin (mTOR) inhibitors have anti-tumor effects against renal cell carcinoma, pancreatic neuroendocrine cancer and breast cancer. In this study, we analyzed the antitumor effects of mTOR inhibitors in small cell lung cancer (SCLC) cells and sought to clarify the mechanism of[r]

Superparamagnetic poly (lactic-co-glycolic acid) (PLGA)-coated Fe3O4 microcapsules are receiving increased attention as potential diagnostic and therapeutic modalities in the field of oncology.

mg/kg, and their inhibition rates were 42.5%, 46.0% and49.9%, respectively. Hydrolyzable polyesters of PCL andPDLLA are useful formulations to encapsulate paclitaxel,ellipticine, and doxorubicin drugs [59-61]. Further, anovel poly(ethyl ethylene phosphate) (PPE, polypho-s[r]

P=120–200 μm). Both the depthof the cold worked layer and the levelofhardness(HV50)increasedwith anincreaseintheabrasiveparticlesize.Thelargestparticles (dp= 200 μm) provided an increase in hardness up to HM=350 HV, and theyextended the hardened layer to a depth of 350μm.Tosha <[r]

porting P-type ATPase similar to the Menkes gene. Nature Genet.5, 327–337.2. Kaler, S.G., Gallo, L.K., Proud, V.K., Percy, A.K., Mark, Y.,Segal, N.A., Goldstein, D.S., Holmes, C.S. &amp; Gahl, W.A. (1994)Occipital horn syndrome and a mild Menkes phenotype associatedwith splice site mutati[r]

Low Carbon Green Growth Roadmap for Asia and the Pacific : Case Study - Europe’s environmental tax and fiscal reformsProductivity and environmental tax reform in Europe project (petrE): Assessing productivity impacts of ETR andEFRAnother modelling exercise conducted as pa[r]

other. Thus, the sufficient silicate reactions lead to considerableformation of low melting silicates which result in lower IDT andST of the ash of biomass adding SiO2 (especially IDT), and thealumina-silication reactions of potassium chlorides and sulfates([r]

Increasing studies implicate cancer stem cells (CSCs) as the source of resistance and relapse following conventional cytotoxic therapies. Few studies have examined the response of CSCs to targeted therapies, such as tyrosine kinase inhibitors (TKIs). We hypothesized that TKIs would have differential[r]

event. In the concept ‘bachelor’, discussed first by Katz and Fodor (1963)intermsoffeature matrices, then by Fillmore (1982)andLakoff(1987) in the cognitive frame-work, a partial fit is observed between an Idealized Cognitive Model of ‘bachelor’ andthe concept of ‘bachelor’ as app[r]

Many of these compounds are also found in herbalmedicines. A number of polyphenols cause carcinogeninactivation, antiproliferation, cell-cycle arrest andinhibition of angiogenesis [10,11]. Polyphenols arepredominantly in sugar-conjugated forms but undergoenzymatic cleavage into[r]

Transfer and Other Phenomena, AIChE J., 18, 1121–1132.Clausing, A. M., and Chao, B. T. (1965). Thermal Contact Resistance in a Vacuum Environ-ment,” J. Heat Transfer, 87, 243–251.Cooper, M. G., Mikic, B. B., and Yovanovich, M. M. (1969). Thermal Contact Conductance,Int. J[r]

SEPTIC SHOCK AND MULTI-ORGANFAILURESSEPTIC SHOCK AND MULTI-ORGANFAILURE᭹Phase II: These mediators are systemically distributed.Normally anti-inf lammatory mediators such as IL-10ensure that the systemic response is limited᭹Phase III: An overwhelming systemic cytokine ‘storm’ leadsto th[r]

NANO EXPRESS Open AccessElectrical resistance of CNT-PEEK compositesunder compression at different temperaturesMohammad Mohiuddin*and Suong Van Hoa*AbstractElectrically conductive polymers reinforced with carbon nanotubes (CNTs) have generated a great deal of scientifican[r]