PROLIFERATION OF MOUSE FIBROBLASTS

Aldehyde dehydrogenase 1A3 (ALDH1A3) has been implicated in the survival and proliferation of prostate cancer cells.

6.5.2 And on to syntax…
I have considered syntax on a very abstract level, i.e. , whether it was flexible enough to allow TFBS turnover. If the maps presented in Section 6.3 contain functional TFBSs, then the work on oxytocin and vasopressin regulatory DNA can proceed to syntax ‘in the concrete[r]

Anti-fibrotic drugs such as pirfenidone have been developed for the treatment of idiopathic pulmonary fibrosis. Because activated fibroblasts in inflammatory conditions have similar characteristics as cancer-associated fibroblasts (CAFs) and CAFs contribute actively to the malignant phenotype, we be[r]

The ability of Ngoclinh ginseng (NLG) stem cell extract in controlling the skin aging process in human fibroblasts was investigated. To evaluate the cosmeceutical effects of the extracts on the aging process, MTT assays were conducted with various concentrations of NLG stem cells. No extracts showed[r]

regulated in treated fibroblasts. Over-expression of IAPs suppresses apoptosis induced by TNF, Fas, chemotoxins and UV-irradiation (Duckett et al., 1998). Moreover, human CIAPs interact with TNF-RII via association with TRAF-1 and TRAF-2 (Rothe et al., 1995), and CIAP-1 has been[r]

Formation of single-cell-based cardiomyocytes and fibroblast network model
For the precise evaluation of cell-to-cell connection of cardiomyocytes and fibroblasts quantitatively, especially to compare the characteristics before and after their connection to be formed an[r]

Activated pancreatic stellate cells (PaSCs) are the key cellular source of cancer-associated fibroblasts in the pancreatic stroma of patients with pancreatic ductal adenocarcinoma (PDAC), however, the activation mechanism of PaSCs is not yet known.

Sang CN, Gracely RH, Max MB, Bennett GJ. Capsaicin- evoked mechanical allodynia and hyperalgesia cross nerve territories. Evidence for a central mechanism. Anesthesiology 1996; 85: 491-496.
Sarafi MN, Garcia-Zepeda EA, MacLean JA, Charo IF, Luster AD. Murine monocyte chemoattractant[r]

Results PDA-66 inhibits proliferation and metabolic activity of ALL cells The influence of PDA-66 on proliferation and metabolic activity in ALL cell lines SEM, RS4;11, Jurkat and MOLT4 [r]

doi:10.1111/j.1742-4658.2008.06853.x
Mitochondrial thymidine kinase (TK2) catalyzes the phosphorylation of thymidine in mitochondria. Its function becomes essential for dTTP syn- thesis in noncycling cells, where cytosolic dTTP synthesis via R1 ⁄ R2 ribo- nucleotide reductase and thymidine[r]

Proliferation assay
The principles of sulforhodamine B (SRB) colorimetric assay were described earlier [21]. This protocol was used in the current study with the following modifications. Fibroblasts or CSCC7 cells were seeded in 96 well plates at densities of 2.5×10 3 o[r]

Nuclei Basement membrane
Cancer development and innate immune cells
How then do chronically activated innate immune cells participate in cancer development? Which mechanisms and which inflammatory-cell-derived mediators are relevant for specific human malignancies — do these depend on organ,[r]

RT-PCR analysis of c-jun, p53 and p21 WAF1/CIF1 in liver and lung of control, chronic vitamin A-deficiency and hypervitaminosis rats
Based on the results found in the differential display study and taking into account the role that p53 plays in the control of cellular proli[r]

The mechanism by which these cells are recruited to breast tumors in MMTV-PymT mice is multifactorial, and may be related to vascular permeability and local factors released by tumor cells, stromal cells, and inflammatory cells. Elaboration by these cells of the inflammatory chemokine CCL2 (M[r]

Nuclear factor erythroid 2–related factor 2 (Nrf2) is involved in cell proliferation by promotion of metabolic activity. It is also the major regulator of antioxidants and has a pivotal role in tumor cell proliferation and resistance to chemotherapy.

Looking at the bottom, you can see the very simple mechanics: a motor drives the differential gear with a 1:1 ratio (Figure 17.2). Combined with the large diam- eter of the wheels, this makes our mouse very fast. Exactly what we wanted.
The front caster wheel is the key to the turnin[r]

Diabetes Mellitus
Type I diabetes mellitus (DM) results in a cell-mediated autoimmune attack against insulin-secreting pancreatic
b -cells. Insulin regulates glucose homeostasis and, in particular, it reduces glycemia when glucose exceeds in blood. Glucose accumulation, which is typical of