PROGNOSTIC CONTRIBUTION OF MAMMOGRAPHIC BREAST DENSITY AND HER2 OVEREXPRESSION TO THE NOTTINGHAM PROGNOSTIC INDEX IN PATIENTS WITH INVASIVE BREAST CANCER
Tìm thấy 10,000 tài liệu liên quan tới tiêu đề "Prognostic contribution of mammographic breast density and HER2 overexpression to the Nottingham Pro...":
Prognostic contribution of mammographic breast density and HER2 overexpression to the Nottingham Prognostic Index in patients with invasive breast cancer
To investigate whether very low mammographic breast density (VLD), HER2, and hormone receptor status holds any prognostic significance within the different prognostic categories of the widely used Nottingham Prognostic Index (NPI).
PROGNOSTIC VALUE OF ERBB4 EXPRESSION IN PATIENTS WITH TRIPLE NEGATIVE BREAST CANCER
Triple-negative breast cancer (TNBC) is known for aggressive biologic features and poor prognosis. Epidermal growth factor receptor (EGFR) overexpression in TNBC indicates poor prognosis. However, there is no previous study of the relationship between expression of the entire human epidermal growth[r]
BÁO CÁO HÓA HỌC:" PAR1 IS SELECTIVELY OVER EXPRESSED IN HIGH GRADE BREAST CANCER PATIENTS: A COHORT STUDY" DOCX
patients progression. The aim of this study was to determine whether PAR1 expression could beused as predictor of metastases and mortality.Methods: In a cohort of patients with infiltrating ductal carcinoma studied longitudinally[r]
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THE EFFECTS OF LYMPH NODE STATUS ON PREDICTING OUTCOME IN ER+ /HER2- TAMOXIFEN TREATED BREAST CANCER PATIENTS USING GENE SIGNATURES
Lymph node (LN) status is the most important prognostic variable used to guide ER positive (+) breast cancer treatment. While a positive nodal status is traditionally associated with a poor prognosis, a subset of these patients respond well to treatment and achieve long-term survival.
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IMMUNOHISTOCHEMICAL SUBTYPES PREDICT THE CLINICAL OUTCOME IN HIGH-RISK NODE-NEGATIVE BREAST CANCER PATIENTS TREATED WITH ADJUVANT FEC REGIMEN: RESULTS OF A SINGLE-CENTER RETROSPECTIVE STUDY
ALND: Axillary lymph node dissection; BC: Breast cancer; CI: Confidence interval; CMF: Cyclophosphamide, methotrexate, 5FU; COS: Comité d ’ Orientation Stratégique; DDFS: Distant disease-free survival; DFS: Disease-free survival; DMAC: Data management and analysis center; ER: Es[r]
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DETECTION OF CIRCULATING TUMOR CELLS USING MANUALLY PERFORMED IMMUNOCYTOCHEMISTRY (MICC) DOES NOT CORRELATE WITH OUTCOME IN PATIENTS WITH EARLY BREAST CANCER – RESULTS OF THE GERMAN SUCCESS-
Recently, the prognostic significance of circulating tumor cells (CTCs) in primary breast cancer as assessed using the Food-and-Drug-Administration-approved CellSearch® system has been demonstrated.
MUTANT P53 GAIN OF FUNCTION INDUCES HER2 OVER-EXPRESSION IN CANCER CELLS
HER2 over-expression is related with a poor prognosis in patients with invasive breast cancer tumors. Clinical associations have reported that somatic mutations of p53 more frequently detected in cases of sporadic breast cancer of the HER2 subtypes, besides a high percentage of HER2-amplifying tumor[r]
RELATIONSHIP BETWEEN THE KI67 INDEX AND ITS AREA BASED APPROXIMATION IN BREAST CANCER
The Ki67 Index has been extensively studied as a prognostic biomarker in breast cancer. However, its clinical adoption is largely hampered by the lack of a standardized method to assess Ki67 that limits inter-laboratory reproducibility.
STAGE OF BREAST CANCER AT DIAGNOSIS IN NEW ZEALAND: IMPACTS OF SOCIO-DEMOGRAPHIC FACTORS, BREAST CANCER SCREENING AND BIOLOGY
Examination of factors associated with late stage diagnosis of breast cancer is useful to identify areas which are amenable to intervention. This study analyses trends in cancer stage at diagnosis and impact of socio-demographic, cancer biological and screening characteristics on cancer stage in a p[r]
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WHOLE BLOOD MICRORNAS AS POTENTIAL BIOMARKERS IN POST-OPERATIVE EARLY BREAST CANCER PATIENTS
microRNAs (miRNAs) are considered promising cancer biomarkers, showing high reliability, sensitivity and stability. Our study aimed to identify associations between whole blood miRNA profiles, presence of circulating tumor cells (CTCs) and clinical outcome in post-operative early breast cancer patie[r]
IMPORTANCE OF HEREDITARY AND SELECTED ENVIRONMENTAL RISK FACTORS IN THE ETIOLOGY OF INFLAMMATORY BREAST CANCER: A CASECOMPARISON STUDY
To assess the importance of heredity in the etiology of inflammatory breast cancer (IBC), we compared IBC patients to several carefully chosen comparison groups with respect to the prevalence of first-degree family history of breast cancer.
NKTR-102 EFFICACY VERSUS IRINOTECAN IN A MOUSE MODEL OF BRAIN METASTASES OF BREAST CANCER
Brain metastases are an increasing problem in women with invasive breast cancer. Strategies designed to treat brain metastases of breast cancer, particularly chemotherapeutics such as irinotecan, demonstrate limited efficacy.
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Quality of life and psychological distress during cancer: A prospective observational study involving young breast cancer female patients
Despite the possible traumatic significance of cancer and of the incidence, prevalence, and survival of young women with breast cancer, these patients are underrepresented in multidimensional research. In the present survey, QoL and psychological distress were studied in a sample of young female bre[r]
CLINICOPATHOLOGICAL FACTORS INFLUENCING THE OUTCOMES OF SURGICAL TREATMENT IN PATIENTS WITH T4A HYPOPHARYNGEAL CANCER
The purpose of this study was to determine prognostic factors influencing outcomes of surgical treatment in patients with T4a hypopharyngeal cancer.
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EVOLUTION OF QUALITY OF LIFE IN PATIENTS WITH BREAST CANCER DURING THE FIRST YEAR OF FOLLOW-UP IN MOROCCO
Quality of life has an important place in the future of patients with breast cancer. The objective of this study is to assess the evolution of the patient’s quality of life with breast cancer in Morocco after a year of follow-up.
SENTINEL LYMPH NODE BIOPSY AFTER NEOADJUVANT CHEMOTHERAPY FOR BREAST CANCER: RETROSPECTIVE COMPARATIVE EVALUATION OF CLINICALLY AXILLARY LYMPH NODE POSITIVE AND NEGATIVE PATIENTS, INCLUDING
To evaluate the accuracy of sentinel lymph node biopsy (SLNB) after neoadjuvant chemotherapy (NAC) in breast cancer patients with axillary lymph node (ALN) metastasis. Methods: A total of 122 patients with operable breast cancer were enrolled in this single-center retrospective study.
Overexpression of KCNJ3 gene splice variants affects vital parameters of the malignant breast cancer cell line MCF-7 in an opposing manner
tein with two transmembrane α -helices per subunit;
therefore, the subcellular localization of fluorescent chi- maeras in membranes is expected to indicate successful overexpression of the entire protein. Indeed, expression of C-termin[r]
therefore, the subcellular localization of fluorescent chi- maeras in membranes is expected to indicate successful overexpression of the entire protein. Indeed, expression of C-termin[r]
POST-DIAGNOSTIC ANTIPSYCHOTIC USE AND CANCER MORTALITY: A POPULATION BASED COHORT STUDY
Many antipsychotics elevate prolactin, a hormone implicated in breast cancer aetiology however no studies have investigated antipsychotic use in patients with breast cancer. This study investigated if antipsychotic use is associated with an increased risk of cancer-specific mortality among breast ca[r]
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Oxalate induces breast cancer
These proliferation experiments showed that oxalate at concentrations of 20 and 50 μM induces significantly higher rates of proliferation of MCF-7, MDA-MB231 cell lines after three days of treatment as determined by Two-way ANOVA with Holm-Sidak’s multiple c[r]
THE PROGNOSTIC VALUE OF STROMAL AND EPITHELIAL PERIOSTIN EXPRESSION IN HUMAN BREAST CANCER: CORRELATION WITH CLINICAL PATHOLOGICAL FEATURES AND MORTALITY OUTCOME
PN is a secreted cell adhesion protein critical for carcinogenesis. In breast cancer, it is overexpressed compared to normal breast, and a few reports suggest that it has a potential role as a prognostic marker.
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