ADVERSE DRUG REACTIONS IN OLDER ADULTS: A RETROSPECTIVE COMPARATIVE ANALYSIS OF SPONTANEOUS REPORTS TO THE GERMAN FEDERAL INSTITUTE FOR DRUGS AND MEDICAL DEVICES
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Progressive bone pain and fracture and abnormal positron emission tomography combined with a computed tomography are main reasons for the oncologists suspecting bone tumor. During the patient’s medical treatment, the oncologists’ unfamiliarity with adverse reactions to anti-HBV drugs were main reaso[r]
Vaccination with swine influenza vaccine is known to increase the risk for Guillain-Barré syndrome ( 30–34 ). Reports of Guillain-Barré syndrome after any vaccination are considered serious and followed up by VAERS to obtain additional information. An[r]
Although numerous publications have appeared on CE-MS, this technique is still developing to be widely accepted for routine use. The major limitation of CE is the limited sample volumes that can be analysed without compromising separation effic[r]
Nonspecific distribution and uncontrollable release of drugs in conventional drug delivery systems (CDDSs) have led to the development of smart nanocarrier-based drug delivery systems, which are also known as Smart Drug Delivery Systems (SDDSs). SDDSs can deliver drugs to the target sites with reduc[r]
Drug-induced liver injury (DILI) is a critical issue in drug development because DILI causes failures in clinical trials and the withdrawal of approved drugs from the market. There have been many attempts to predict the risk of DILI based on in vivo and in silico identification of hepatotoxic compou[r]
The global rise in aging population led to the increase of the number of elderly patients with lung cancer. Due to the impairment of the function of multiple organs, the work-up and treatment NSCLC for older patients become more difficult than adults.
In this work, we further enhance our computational framework for breast cancer drug repurposing by visualizing the prospected dynamic gene expression after the treatment. Practically, the most challenging problem in drug repurposing is to prioritize the list of drugs for further in vivo validation a[r]
We also used GLC4 cells to investigate CsA and its analogs in the absence of disturbing effects mediated by inhibition of P-glycoprotein pumps. Analyses with DCF as probe for assessment of ROS production showed, for all three analogs,
Definitions AF is a supraventricular tachyarrhythmia characterised by uncoordinated atrial activation with subsequent deterioration of atrial mechanical function. On the electrocardiogram, AF is described by the replacement of consistent P waves with rapid oscill[r]
There are no reports on investigations of the characteristics of adverse drug reaction (ADR) reports for pediatric patients in the Japanese Adverse D.rug Event Report database (JADER) and the utility of database for drug safety surveillance in these patients
administration of a drug when it is not intended. Expense is another consideration. Oral Ingestion Absorption from the gastrointestinal tract is governed by factors such as surface area for absorption, blood flow to the site of absorption,
sues within a group of eight different C57 ⁄ Bl6 mice. A second step would involve the measurement of the activity levels of signaling pathways, indicated by, for example, the phospho- ⁄ nonphospho ratios of pathway components.[r]
Case Study in Finance in Latrobe University. In this case study, we analysis CS energy in Australia. The company now has a tendency to create and operate a nuclear station the town of Mount Isa in Northwestern Queensland after finishing the planning for this project. In this report, we will assess t[r]
In this chapter, a comparative analysis of idiomatic expressions containing the word „eye‟ in English and Vietnamese equivalents will be given to find out the differences and similaritie[r]
The optimal choice of cytotoxic drugs for intraperitoneal chemotherapy (IPC) in conjunction with cytoreductive surgery (CRS) for treatment of peritoneal carcinomatosis (PC) is poorly defined. We investigated drug sensitivity ex vivo in patient samples of various PC tumor types and correlated clinica[r]
Drug resistance is a common cause of treatment failure in cancer patients and encompasses a multitude of different mechanisms. The aim of the present study was to identify drugs effective on multidrug resistant cells.
Task one : English – Vietnamese translation 1. Scientists have found some experimental evidence for dark matter. Astronomers at Bell Labs in the United States found evidence for dark matter in an image taken by the Hubble Space Telescope (HST) in 1997.[r]
136 Table 30 Fit Indices of the Measurement Model for Life Satisfaction – Male Older Adults 137 Table 31 Fit Indices for the Independence Model of Life Satisfaction – Male Older Adults 1[r]
A common approach to cancer therapy in clinical practice is the combination of several drugs to boost the anticancer activity of available drugs while suppressing their unwanted side effects. s. In this regard, we examined the efficacy of combination treatment with the widely-used genotoxic drug dox[r]