fat loss rather than diminution in non-fat body mass as indicated by different means: impedance measure-ments, waist, hip and thigh measurements, and sub-cutaneous fat measurements. Earlier, Udani et al. [20] reported reduced body weights and serum triglyc-erides in 14 obese adults receiving 1500 mg[r]
1. INTRODUCTION Hb J-Meerut results from a C ->A mutation (GCG->GAG) at codon 120 of the α1 or α2 globin gene, changing the alanine to glutamic acid at residue 120 of the α chain [1,2,3]. This variant was first reported in two sisters from Meerut, Utlar Pradesh, India [1][r]
pattern. It is possible that participants who have been diagnosed with a chronic disease may have changed their diet. To address this concern we adjusted for the presence of chronic disease (CHD, cancer, and stroke) and hypertension throughout the analyses. We also repeated the analyses exclu[r]
of wild type BRCA1 and BRCA2, DSBs can be efficiently repaired by RAD51 mediated homologous recombination (Fig. 1B). It has been shown that BRCA1 and BRCA2 interact with RAD51, and play essential role in homologous recombination [28, 30, 31]. Thus, in the event of DNA damage associated with PARP inh[r]
3. Department of Medical Technology, Nagoya University School of Health Sciences, 1-1-20 Daikominami, Higashi-ku, Na-goya, 461-8673 Japan Correspondence to: Simon Itou, Department of Preventive Medicine / Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, 65 Ts[r]
Exon 1 (transcript variant 3) and exon 10 were amplified from selected samples with PCR parameters as described above. After a control electrophoresis on 2% agarose gels, the PCR products were directly subjected to processing with Surveyor nuclease [13] (Transgenomic, Omaha, USA) according to[r]
tion. Exercise is a known stress condition that con-sumes muscle glycogen rapidly. During the recovery period following exercise, the whole-body glucose tolerance and the rate of muscle glycogen storage in-creases simultaneously, resulting in glycogen super-compensation [5]. This normal adapt[r]
isolated Japanese H. pylori strains (J-HM-CAP) ELISA (Kyowa Medex, Tokyo, Japan), were used for the identification of H. pylori-infected participants (in the control group the former was used and in the case group both were used.). An ELISA value of 2.3 or over was regarded as positive for both test[r]
exclude opportunistic brain infection, however of the eight lumbar punctures that were performed, no op-portunistic infections were found. Similarly, even though HIV-1-infected subjects had advanced immu-nosuppression, there were no individuals who had any history of any opportunistic infections, in[r]
As an example we presented the finding that maternal use of loratadine in early pregnancy was associated with a roughly doubled risk for infant hypospadias. We concluded: “The finding can still be random, but causality cannot be dismissed, even though the mechanism of action is not understood[r]
such as poorly controlled hypertension or diabetes, obstructive pulmonary disease, or significant heart disease. Patients with autoimmune hepatitis or other conditions known to be exacerbated by interferon and ribavirin or known to have hypersensitivity to these drugs should not receive treatment. T[r]
The controls were selected from the study population of 65,383 male births. The control group comprised of 10 controls per case, and these controls had no recorded diagnosis of hypospadias during the first six months post delivery. We matched on birth, month, and year of the child. To examine whethe[r]
replicating HCV RNA. Critical for the usefulness of this system was the identification of specific amino acid substitutions, i.e., cell culture-adaptive changes, that increased the efficiency of replication initiation by several orders of magnitude [9]. With the replicon system it became possible, f[r]
18. Farci P, et al. Hepatitis C virus-associated fulminant hepatic failure. N Engl J Med, 1996. 335(9): 631-4. 19. Vogt M, et al. Prevalence and clinical outcome of hepatitis C infection in children who underwent cardiac surgery before the implementation of blood-donor screening. N Engl J Med, 1999.[r]
acceptable participation rate as well as less selection bias. We have chosen to report from the youngest age cohort participating in “The Prospective Population Study of Women in Gothenburg” as this was the age group in which lung function status was most thoroughly examined and selection bias due t[r]
virus. In this study, HCVRNA was detected more frequently in patients with anti-HCV positive (90.7% of 130) than in patients with HBsAg/anti-HCV positive (65.2% of 69, p<0.001). 5. Antivirus Therapy Few data exist on treatment of double infection. Some preliminary studies [45,46] showed that[r]
of steatosis exist in our patients with HCV. The first type of steatosis occurs secondary to metabolic factors namely alcohol use or the metabolic syndrome. This form of steatosis is not initiated by the hepatitis C virus however it can very well increase the progression of fibrosis ultimately towar[r]
African Americans which may explain a low SVR in this population compared to other groups [13]. African American patients showed significantly lower decrease in HCV RNA over the first 24 hours than Caucasians and significantly longer delay in initial response and significant difference in the[r]