THE ROLE OF NATURE IN CANCER PATIENTS'' LIVES: A SYSTEMATIC REVIEW AND QUALITATIVE META-SYNTHESIS

Systematic reviews, with or without meta-analysis, play an important role today in synthesizing cancer research and are frequently used to guide decision-making. However, there is now an increase in the number of systematic reviews on the same topic, thereby necessitating a systematic review of prev[r]

Enzyme-linked Immunosorbent Assays (ELISAs)
Cells were seeded into 6-well plates and allowed to ad- here overnight. The spent media was removed and centrifuged to remove cell debris. A human TGF- β 1 DuoSet Development ELISA kit (R&D Systems Inc.) was utilised to an[r]

Faulkner, K.A., Redfern, M.S., Cauley, J.A., Landsittel, D.P., Studenski, S.A., Rosano, C.,Simonsick, E.M., Shorr, R.I., Ayonayon, H.N., Newman, A.B., Health, Aging, and BodyComposition Study, 2007. Multitasking: association between poorer performance and ah[r]

The combination of blue dye and radioisotope is most widely used to identify sentinel lymph nodes (SLNs) in patients with breast cancer. However, some individual studies suggested that dual tracers did not have an advantage over radioisotope alone in detecting SLNs. We performed a systematic review[r]

Cancer cachexia is a multifactorial syndrome that dramatically decreases survival. Loss of white adipose tissue (WAT) is one of the key characteristics of cachexia. WAT wasting is paralleled by microarchitectural remodeling in cachectic cancer patients. Fibrosis results from uncontrolled ECM synthes[r]

Several limitations of this meta-analysis must be noted. First, our meta-analysis was not conclusive regarding when CTCs should be evaluated after the initiation of chemotherapy and what levels of CTCs would be useful for clinical prognostication. Sec[r]

MLKL is the most important executor of necroptosis pathway. Recent studies have demonstrated that MLKL could serve as a potential prognostic biomarker for cancer patients. However, most studies reported so far are limited in discrete outcome and sample size.

Case reports, retrospective analyses, and observational studies have linked the use of cisplatin to increased risk of second cancers, especially life-threatening secondary leukemia. We therefore performed a systematic review and meta-analysis to evaluate the risk of second cancers associated with re[r]

We systematically reviewed the evidence for the interaction of microsatellite instability status (MSI) and treatment with 5FU in colorectal cancer to determine how well MSI status predicts health outcomes in patients undergoing 5FU-based chemotherapy.

Several studies have shown, that circulating tumor cells (CTC) have a negative prognostic value in colorectal cancer patients. Aim of this study was to evaluate the role of CTC in specifically rectal cancer patients regarding the influence on overall survival and to elucidate the impact of CTC in pr[r]

Cachexia may occur in 40% of cancer patients, representing the major cause of death in more than 20% of them. The aim of this study was to investigate the role of leptin, ghrelin and obestatin as diagnostic and predictive markers of cachexia in oncologic patients.

One well-accepted strategy for optimising outcomes in mammographic breast cancer screening is to improve communication with women about screening. It is not always clear, however, what it is that communication should be expected to achieve, and why or how this is so. We investigated Australian exper[r]

latent tuberculosis therapy. Isoniazid latent MTB treatment appears effective, causing severe hepatotoxicity in ϳ1%of patients.3. More than 60% of liver transplant recipients with active MTB have extrapulmonary involvement.4. Approximately 35% of patients wi[r]

Cytokines are involved in cancer invasion and metastasis. Circulating tumor cells (CTCs) play key role in tumor dissemination and are an independent survival predictor in breast cancer patients. The aim of this study was to assess correlation between CTCs and plasma cytokines in primary breast cance[r]

The role of laparoscopic resection in patients with clinically suspicious T4 colorectal cancer remains controversial. The aim of this study was to compare the long-term and oncologic outcomes of laparoscopic resection and the open approach in clinical T4 colorectal cancer.

Patients with primary brain tumors are reported to have an elevated level of distress prevalence, due to the functional sequelae and the unfavorable prognosis, but the estimated prevalence of this disorder varies among studies.

The role of post-mastectomy radiotherapy (PMRT) in the treatment of patients with T1–2N1 breast cancer is controversial. This study’s purpose was to evaluate the risk of recurrence of T1–2N1 breast cancer and the efficacy of PMRT in low-, medium- and high-risk groups of patients.

Surgical resection is necessary to conduct a pathological biopsy and to achieve a reduction of intracranial pressure in low-grade gliomas patients. This study aimed to determine whether a greater extent of resection would increase the overall 5-year and 10-year survival of patients with low-grade gl[r]

The aim of this systematic review and meta-analysis was to compare overall survival and disease-free survival after fertility sparing surgery (FSS) vs radical surgery in stage 1 epithelial ovarian cancer (EOC).

25. Misumi S, Endo M, Inatsu A, Hashimoto K, Takamune N, Shoji S: HumanImmunodeficiency Virus-Induced Apoptosis of Human Breast CancerCells Via CXCR4 is Mediated by the Viral Envelope Protein But Does NotRequire CD4. Current HIV Research 2008, 6:34-42.26. Gaughan EM, Dezube BJ,[r]