SERUM IRISIN LEVELS ARE LOWER IN PATIENTS WITH BREAST CANCER: ASSOCIATION WITH DISEASE DIAGNOSIS AND TUMOR CHARACTERISTICS

Irisin is a recently discovered myokine, involved in the browning of white adipose tissue. To date, its function has been mainly associated with energy homeostasis and metabolism, and it has been proposed as a promising therapeutic target for obesity and metabolic diseases. This is the first study i[r]

Meng X-Y, Zhang Z, Davidson NE, Fung ET, Chan DW: Independent validation of candidate breast cancer serum biomarkers identified by mass spectrometry. Clin Chem 2005, 51:2229-2235.24. Mathelin C, Cromer A, Wendling C, Tomasetto C, Rio MC: Serum biomarkers for detection of[r]

To investigate of malnutrition by using indicators: SGA_3, Body Mass Index, serum prealbumin, serum albumin, normalized protein catabolic rate (nPCR) and serum leptin concentration in patients with chronic kidney disease are on Hemodialysis and continuous peritoneal dialysis at Can Tho General Hospi[r]

Cancer antigen (CA) 125 (CA-125) is used in ovarian cancer detection and monitoring, whose serum level has a positive correlation with tumor stage. The aim of this study was to obtain a prediction metastasis equation in a group of patients with ovarian cancer based on Ca-125

A shift towards less burdening and more patient friendly treatments for breast cancer is currently ongoing. In low-risk patients with early-stage disease, accelerated partial breast irradiation (APBI) is an alternative for whole breast irradiation following breast-conserving surgery.

Individual patients differ in their psychological response when receiving a cancer diagnosis, in this case breast cancer. Given the same disease burden, some patients master the situation well, while others experience a great deal of stress, depression and lowered quality of life.

BACKGROUND
Bronchoscopy with 2 sources of light (white and fluorescence) is an advance in diagnosis of lung cancer. The results of many previous studies have shown that the effectiveness of fluorescent light is better than white one. Especially, the efficiency of bronchoscopy in detection of lung c[r]

Delay in the diagnosis of breast cancer in symptomatic women of 3 months or more is associated with advanced stage and low survival. We conducted this study to learn more about the extent and reasons behind diagnosis delay of advanced breast cancer in Moroccan women.

Chapter 100. Megaloblastic Anemias (Part 5) An underlying maternal folate metabolic abnormality has also been postulated. One abnormality has been identified: reduced activity of the enzyme 5,10-methylene-THF reductase (MTHFR) (Fig. 100-1) caused by a common 677CÆT polymorphism in the MTHFR[r]

Lymph node (LN) involvement represents the strongest prognostic factor in colon cancer patients. The objective of this prospective study was to assess the prognostic impact of isolated tumor cells (ITC, defined as cell deposits ≤ 0.2 mm) in loco-regional LN of stage I & II colon cancer patients.

Objectives: To examine the characteristics of concomitant cardiovascular diseases in patients with chronic obstructive pulmonary disease. Subjects and methods: A cross-sectional descriptive study was conducted on 162 patients who had a confirmed diagnosis of chronic obstructive pulmonary disease fro[r]

We aimed to estimate the effect of alcohol consumption on breast cancer risk and to test whether overweight and obesity modifies this association. An increase in breast cancer risk with higher alcohol consumption was found for breast cancers in women with a BMI ≤25 kg/m2.

We also calculated outcome measures for MR- detected intramammary lesions. The cancer detection rate for intramammary lesions was defined as the total number of intramammary cancers detected at MR im- aging per 1000 examinations. The abnormal interpret- ation rate for intramammary lesions was[r]

Methods : This was a retrospective study approved by an institutional review board that included 66 women with cervical cancer treated with definitive chemoradiation who underwent pre-treatment MRI at our institution between 2012 and 2013. A region of interest (ROI) was m[r]

People from lower socioeconomic groups have worse survival outcomes for cancer, which in part reflects later-stage disease at diagnosis. The mechanisms underlying delayed cancer symptom presentation in lower socioeconomic groups are not well understood.

The prognostic significance of FOXP3+ tumor-infiltrating lymphocytes (TILs) in patients with breast cancer remains controversial. The aims of our meta-analysis are to evaluate its association with clinicopathological characteristics and prognostic significance in patients with breast cancer.

Cellular stressors and apoptosis-inducing agents have been shown to induce ribosomal RNA (rRNA) degradation in eukaryotic cells. Recently, RNA degradation in vivo was observed in patients with locally advanced breast cancer, where mid-treatment tumor RNA degradation was associated with complete tumo[r]

Obesity and diabetes are two risk factors for cancer. To evaluate the association of body mass index (BMI) with cancer risk in diabetic patients may improve current understanding of potential mechanisms.

Chronic diseases and multimorbidity are common in western countries and associated with increased breast cancer mortality. This study aims to investigate non-participation in breast cancer screening among women with chronic diseases and multimorbidity and the role of time in this association.

The association between body mass index (BMI) at the time of breast cancer diagnosis and the prognosis of breast cancer patients remains controversial. Furthermore, the association between BMI and prognosis with respect to different breast cancer subtypes is not clearly defined.