BÁO CÁO Y HỌC: "Γ PARADOXICAL ROLES OF IFN-Γ IN MODELS OF TH1-MEDIATED AUTOIMMUNITY" POTX

acute HCV infection persists and 4% to 20% of patients with chronic hepatitis C will develop liver cirrhosis within 20 years. In patients with liver cirrhosis, the risk to develop HCC is 1-5% per year. Current standard therapy is the combination of pegylated interferon-α (PEG-IFN-α) and ribav[r]

Corresponding address: Jin Zhong Li, D.V.M. Ph.D., Department of Neurological Surgery, University of Virginia Health System, P. O. Box 800212, Charlottesville, Virginia 22908, USA Received: 2006.05.02; Accepted: 2006.05.31; Published: 2006.06.01 Osteogenic potentials of some recombinant human bone m[r]

Int. J. Med. Sci. 2007, 4 72International Journal of Medical Sciences ISSN 1449-1907 www.medsci.org 2007 4(2):72-82 © Ivyspring International Publisher. All rights reserved Review Role of Dietary Soy Protein in Obesity Manuel T. Velasquez1 and Sam J. Bhathena1,2 1. Department of Medi[r]

Int. J. Med. Sci. 2007, 4 36International Journal of Medical Sciences ISSN 1449-1907 www.medsci.org 2007 4(1):36-44 © Ivyspring International Publisher. All rights reserved Research Paper Proteomic analysis of mechanisms of hypoxia-induced apoptosis in tro-phoblastic cells Shin-ichi Ishioka,[r]

mortality in women. Familial breast cancer is a small subset of this disease contributing to about 5 to 10% of breast cancer cases. Germline mutations of the breast tumor suppressor genes BRCA1 and BRCA2 have been found to contribute to most of the familial breast cancer cases [1-5]. BRCA1 wa[r]

relatively similar pattern to that found in the untreated control cells. The pairwise comparison analysis demonstrated four significantly up-regulated (COBRA1, ITGB4, STAU2, and HMGN3) genes and one down-regulated (ANK3) gene. All these genes exert their function on transcriptional and transl[r]

pancreatic cells [21]. Consumption of foods with a high content of nitrites and nitrosamines has been associated with type 1 diabetes [22;23]. In addition, advanced glycation and lipo-oxidation end products formed in meat and high fat products through heating and processing have been associat[r]

with peginterferon alfa-2b plus ribavirin in patients with chronic hepatitis C infected with genotype 1 and low pretreatment viremia. J Hepatol. 2006;44(1):97-103. 10. Drusano GL, Preston SL. A 48-week duration of therapy with pegylated interferon alpha 2b plus ribavirin may be too sho[r]

24, the likelihood of an SVR is virtually nil and treatment can be stopped or continued with the only aim to slow liver disease progression in patients with a severe prognosis, without any hope to eradicate infection (Figure 1A) [18, 22]. Ongoing trials are studying whether a prolonged antivi[r]

CagA protein. Science 2002; 295: 683-6. 5. Higashi H, Nakaya A, Tsutsumi R, et al. Helicobacter pylori CagA induces Ras-independent morphogenetic response through SHP-2 recruitment and activation. J Biol Chem 2004; 279: 17205-16. 6. Hatakeyama M. Helicobacter pylori CagA--a potential bacterial oncop[r]

Int. J. Med. Sci. 2006, 3 75International Journal of Medical Sciences ISSN 1449-1907 www.medsci.org 2006 3(2):75-78 ©2006 Ivyspring International Publisher. All rights reserved Review Antiviral therapy of HCV in the cirrhotic and transplant candidate Steven K. Herrine, and Victor J. Navarro Divisio[r]

Int. J. Med. Sci. 2007, 4 98International Journal of Medical Sciences ISSN 1449-1907 www.medsci.org 2007 4(2):98-104 © Ivyspring International Publisher. All rights reserved Research Paper No associations of Helicobacter pylori infection and gastric atrophy with plasma total homocysteine in Japanes[r]

severe with occasional lymphoid aggregates (Figure 2) [4,11]. Actively proliferating bile ductiles are often seen. Risk factors for severe recurrent HCV include advanced donor age, HCV genotype 1, high HCV RNA levels before and after transplant, early histological recurrence of HCV, concomita[r]

1 4 1. Department of Hospital Pharmacy, School of Medicine, Kobe University, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan 2. Clinical Pathology and Immunology, Department of Biomedical Informatics, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Ko[r]

Int. J. Med. Sci. 2006, 3 79International Journal of Medical Sciences ISSN 1449-1907 www.medsci.org 2006 3(2):79-83 ©2006 Ivyspring International Publisher. All rights reserved Review Management of HCV Infection and Liver Transplantation Thomas D. Schiano, and Paul Martin Adult Liver Transplantation[r]

healthy, middle-aged men the C genotype was associated with elevated levels of low-density lipoprotein (LDL) cholesterol and apolipoprotein B (Apo B). In 580 male subjects with hyperlipidaemia recruited from the West of Scotland Coronary Prevention Study (WOSCOPS) carriers of the C allele had signif[r]

yk23724@gipac.shinshu-u.ac.jp Received: 2006.03.25; Accepted: 2006.06.30; Published: 2006.07.12 Background: Helicobacter pylori has now been widely recognized as a causative agent of gastroduodenal diseases. The development of safer anti- H. pylori compounds is desirable due to the antibiotic-resist[r]

change in muscle strength (r=0.73, P=0.001). Group assignment was be the only independent predictor of hSGLT3 transcript levels, explaining 68% of its variability (P=0.01). Our data show that hSGLT3, but not GLTU4, expression was enhanced in skeletal muscle after 16 weeks of resistance training. Thi[r]

based regimens were unfavorable, leading to concern for the safety of such an approach. Crippin and colleagues randomized end-stage liver disease patients on the transplant waiting list to three dose regimens: interferon alfa-2b, 1 million units (MU) daily, interferon alfa-2b 3MU t.i.w., and[r]

Visser R, Harrington M. European study on epidemiology and the management of HCV in the haemodialysis population—Part 1:centre policy. EDTNA ERCA J. 2004; 30(2):84-90. 66. Angelico M, Tisone G, Rapicetta M, Pisani F, Gandin C, Chionne P, Dettori S, Iaria G, Danese V, Orlando G, Casciani CU. H[r]