DELIVERING EARLY CARE IN DIABETES EVALUATION (DECIDE): A PROTOCOL FOR A RANDOMISED CONTROLLED TRIAL TO ASSESS HOSPITAL VERSUS HOME MANAGEMENT AT DIAGNOSIS IN CHILDHOOD DIABETES
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There is increased incidence of new cases of type 1 diabetes in children younger than 15 years. The debate concerning where best to manage newly diagnosed children continues. Some units routinely admit children to hospital whilst others routinely manage children at home.
The WIDA-trial had no ‘ real ’ randomized control group because we used an additional group to control secular effects and the observation period of this group was shorter. GPs in the control group showed a small but significant knowledge gain that was lower than in
Diabetic tissue damage This may be present when a person applies for a job, or may develop during employ- ment. People with diabetes may fail to appreciate the existence or significance of complications. Visual loss from diabetic eye disease, retinopathy, or cat[r]
In this context, we performed two trials with one single intraarticular injection of IL-1ra in knee OA [7,8]. Th e main result of the randomised, placebo-controlled trial using two doses of IL-1ra (50 mg and 150 mg) was negative regarding the evolution of pain[r]
HIV infection in a family may affect optimum child development. Our hypothesis is that child development outcomes among HIV-exposed infants will be improved through a complex early childhood stimulation (ECS) programme, and income and loans saving programme for HIV positive parents.
High-volume versus standard-volume haemofiltration for septic shock patients with acute kidney injury (IVOIRE study): a multicentre randomized controlled trial Intensive Care Medicine S[r]
Initial scheduled insulin, dose deci- sions, and correction-dose calcula- tions. The initial doses of scheduled subcutaneous insulin are based on previ- ously established dose requirements, pre- vious experience for the same patient during similar circumstances of nutri- tional change or dr[r]
Most adolescents aged 10-19 years with diabetes have type 1, an autoimmune form of the disease in which the pancreas produces little or no insulin. Without insulin, fat and sugar remain in the blood and eventually can damage vital organs. Acute complications such as ketoac[r]
The authors thank Stephanie Zaza, MD, MPH, for support, technical assistance, and editorial review; Kristi Riccio, BSc, for technical assistance; and Kate W. Harris, BA, for editorial and technical assistance. The authors acknowledge the fol- lowing consultants for their[r]
Limitations This study had a number of limitations. First, although the non-response analysis indicated that the sample was rep- resentative in all but one of the measured variables (number of years since professional qualification), the response rate was low (40% at the indiv[r]
However, when preparing to conduct either analysis it is essential to con- struct a scatter diagram of the values of one of the variables against the values of the other variable. By drawing a scatter diagram one can see imme- diately whether or not there is any visual evidence[r]
Convulsive status epilepticus (CSE) is the most common life-threatening childhood neurological emergency. Despite this, there is a lack of high quality evidence supporting medication use after first line benzodiazepines, with current treatment protocols based solely on non-experimental evidence and[r]
In this paper a new fuzzy model (FMOTPD2) is developed and by this model the measures of beliefs are determined so that one of the groups of possible therapeutic procedures is optimal for each patient of type 2 diabetes on hospital treatment. The choice of therapeutic procedure on individual level,[r]
Childhood obesity and early puberty are intermediate risk factors for later metabolic and reproductive disorders including diabetes, polycystic ovarian syndrome (PCOS), and breast cancer.
Once consented, participants were randomised to treatment as usual from their general practice (controls) or the practice nurse led intervention. The intervention includes a specially prepared education booklet and a compre- hensive baseline assessment of participants ’ m[r]
Type 1 diabetes (T1D) is a chronic metabolic condition requiring intensive daily self-care to avoid both high and low blood glucose levels. Self-care and glycemic outcomes are particularly problematic in adolescence, a period known for its increased risk of emotional problems.
Immediate intervention HTH case-management intervention was based on the lat- est guidelines for the management of CHD risk factors, particularly those reflecting cholesterol management [22,23], hypertension [24], physical activity [25], diabetes [26], aspirin th[r]
Schools We began with a pool of 66 elementary schools in two adminstrative areas of the school district. Schools were excluded if all the students attending the school received special education or other special services; the school was operated by an entity other than the school sys[r]
The purpose of this study was to test the feasibility of a randomised controlled trial comparing six weeks of humanistic school-based counselling versus waiting list in the reduction of emotional distress in young people, and to obtain initial indications of efficacy.
Photodynamic therapy (PTD) involves the local activation of a systemically administered photosensitising agent by non- ionising radiation in the form of non-thermal laser light. Many of the sensitising agents that have been studied have been products of porphyrin metabolism such as 5[r]