INTRODUCTION Studies using the human hepatocellular carcinoma HCC cell line HepG2 have demonstrated a specific gene expression pattern induced by ethanol different from that observed in [r]
HSGLT3 AND GLUT4 GENE EXPRESSION As shown in Figure 1, the median relative expression ratio 2-ΔΔCt of hSGLT3 transcript levels in skeletal muscle increased by a factor of 10.02 after 16 [r]
The aim of this study was to characterize global changes of apoptosis-related proteins induced by hypoxia in trophoblastic cells so as to clarify the mechanism of hypoxia-induced apoptos[r]
In the present case a slight increase in the oxygen affinity of Hb J Meerut, relative to that of the normal control, has been observed as detected by low p50 values in arterial whole blo[r]
We identified a sufficient number of epidemiologic studies on lung cancer to conduct a meta-analysis for genetic polymor-phisms in nucleotide excision repair pathway genes, focusing on x[r]
A recombinant first-generation adenovirus ADrBMP6 was constructed and compared with ADhBMP6 in the process of bone formation_._ In the second set of experiments, human _BMP6_ cDNA was co[r]
The association of type 2 DM with unprocessed meat intake g/day and the frequency of consumption of processed meat was evaluated using the Cox model with adjustment for age, kcals/day, b[r]
Therefore, the observation that only one heterozygous mutation with no consequence on the translated protein was found while screening 14 exons of 35 patient samples suggests that mutati[r]
Metabolic steatosis is not triggered in anyway by the hepatitis C virus however the combination of this form of steatosis and the presence of HCV has been associated with a more rapid pr[r]
At such low concentration, ethanol-induced apoptosis in human hepatocellular carcinoma HepG2 cells is triggered by activation of the Fas receptor [12], a member of the tumor necrosis fam[r]
RISK FACTORS FOR ADVANCED PROGRESSION OF LIVER Fibrosis Risk Factors Alcohol consumption >30 g/day in males, >20 g/day in females Age at time of infection > 40 years Male gender Degree [r]
In general, immune factors prior to treatment or early in treatment do not predict sustained viral response SVR, defined as negative serum test for HCV RNA 6 months after completion of t[r]
Totally, the risk factors of dual infection are similar to those of single infection of the two viruses, including IDU, blood transfusion, unsafe sexual contact, and other parenteral tra[r]
Treatment should be individualized in patients with the following characteristics: 1 acute HCV infection; 2 coinfection with HIV; 3 under 18 years of age; 4 chronic renal disease, on or [r]
E-mail : jean-michel.pawlotsky@hmn.aphp.fr Received: 2006.01.12; Accepted: 2006.03.15; Published: 2006.04.01 The use of serological and virological tests has become essential in the mana[r]
In the second published pivotal trial of combined therapy with pegylated interferon and ribavirin, cirrhotic patients treated with peginterferon alfa-2a plus ribavirin for 48 weeks had S[r]
Although a well designed study from Europe did show a higher rate of graft failure in HCV recipients of live donor liver transplantation as compared to HCV+ recipients of deceased donor [r]
In the second published pivotal trial of combined therapy with pegylated interferon and ribavirin, cirrhotic patients treated with peginterferon alfa-2a plus ribavirin for 48 weeks had S[r]
In particular, HCV entry, cytoplasmic release and uncoating, the initial steps of replication, virus assembly, the release of viral progeny, and the detailed virion structure will be cha[r]