INTEREST OF PREOPERATIVE IMMUNONUTRITION IN LIVER RESECTION FOR CANCER: STUDY PROTOCOL OF THE PROPILS TRIAL, A MULTICENTER RANDOMIZED CONTROLLED PHASE IV TRIAL
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Statistical methods Sample size calculation The hypothesis of this phase IV trial is that immunonu- trition will reduce overall postoperative 30-day morbid- ity rate. The sample size calculation is based on the detection of significant difference
Chapter 133. Tetanus (Part 4) Tetanus: Treatment General Measures The goals of therapy are to eliminate the source of toxin, neutralize unbound toxin, and prevent muscle spasms while monitoring the patient's condition and providing support—especially respiratory s[r]
twice a day, once after breakfast and once after dinner, for 14 consecutive days, followed by a 7-day rest period. If the patients exhibit toxicities that meet the reduction criteria, the oxaliplatin dose of 130 mg/m 2 will be grad- ually reduced to[r]
Work is a central resource for cancer survivors as it not only provides income but also impacts health and quality of life. Additionally, work helps survivors to cope with the perceived critical life event. The German Pension Insurance provides medical rehabilitation for working-age patients with ch[r]
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly[r]
Self-management is becoming essential for breast cancer survivors, but evidence about the effectiveness of self-management support (SMS) intervention is lacking. To address this issue, we developed a theory-based SMS intervention, the ‘EMPOWER’, aimed at empowering breast cancer survivors. Here we d[r]
of 150 women. This analysis will be done by an independ-ent Data and Safety Monitoring Committee (DSMC) thatwill not be aware of the allocation of treatment. The sta-tistical analysis will be performed according to O'BrienFleming's rule. The decision to unbl[r]
Discussion In recent years, various interventions have been utilised to improve medication adherence to AI therapy for breast or other types of cancer [37, 38]. A pilot rando- mised controlled trial of a web-enabled application to prov[r]
This phase II bridging study assessed the safety and efficacy of nab-paclitaxel/gemcitabine (Metastatic Pancreatic Adenocarcinoma Clinical Trial [MPACT] regimen) in Chinese patients with metastatic pancreatic cancer (MPC).
4Department of Psychiatry, Case Western Reserve University, Cleveland, OH, USA and 5Department of Physical Education and Recreation, University of Alberta, Edmonton, AB, CanadaEmail: Vivian E von Gruenigen* - vivian.vongruenigen@UHhospitals.org; Heidi E Gibbons - heidi.frasure@U[r]
mary objectives, a significantly higher proportion ofBEXIDEM versus BCG-treated patients experienced BCrecurrence. The agents applied were applied correctly, i.e.BCG in accordance to the current EAU- guidelines andBEXIDEM dosing and regimen in accordance to priorph[r]
Prospective trials have demonstrated the advantage of dose-escalated radiotherapy for the biochemical and clinical control of intermediate risk prostate cancer. Dose escalation improves outcomes but increases risks of urinary and bowel toxicity.
Cervical dysplasia (cervical intraepithelial neoplasia (CIN)) is caused by Human Papillomavirus (HPV) and is most common in women of reproductive age. Current treatment of moderate to severe CIN is surgical.
Cancer-related fatigue is a common problem in persons with cancer, influencing health-related quality of life and causing a considerable challenge to society. Current evidence supports the beneficial effects of physical exercise in reducing fatigue, but the results across studies are not consistent,[r]
(page number not for citation purposes)pated in its design and coordination and helped to draftthe manuscript. All authors read and approved the finalmanuscript.AcknowledgementsWe wish to thank the participants and their families for their involvement in thi[r]
treatment by LLETZ. Follow-up visits are anchored to the start of the treat- ment (either imiquimod or LLETZ). Cytological assess- ment will be performed by two independent trained cytology analysts, according to the Papanicolaou system. In case of inconsi[r]
Cancer related fatigue (CRF) is one of the most prevalent and distressing long-term complaints reported by (non-) Hodgkin survivors. To date there has been no standard treatment for CRF in this population. A novel and promising approach to treat CRF is exposure to bright white light therapy
bacterial vaginosis with clindamycin during pregnancy have not reduced adverse pregnancy outcomes. Numerous trials of oral metronidazole treatment during pregnancy have given inconsistent results, and a 2007 Cochrane review concluded that antenatal treatment of women with bacter[r]
[PMID: 16371037] Hebert PC et al: A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. N Engl J Med 340:409, 1999 [PMID: 9971864] Hillyer CD et al (eds): Blood Banking and Transfusion Medicine: Basic Princ[r]