A PROBE CAN CAPTURE CIRCULATING TUMOR CELLS (CTC) – AN ANTITUMOR ANTIBODY BASED CAPTURE TECHNIQUE

The study was conducted with a objective to find a suitable, cost effective technique to capture CTC’s and to develop minimal invasive method for diagnosing tumor/cancer. In the present study polystyrene was used as a matrix to capture circulating tumor cells by using EpCAM antibodies.

The assessment of circulating tumor cells (CTCs) has been shown to enable monitoring of treatment response and early detection of metastatic breast cancer (MBC) recurrence. The aim of this study was to compare a well-established CTC detection method based on immunomagnetic isolation with a new, filt[r]

Background
While progress has been made on the prevention and treatment of primary cancers, metastases to distant sites remain a major clinical challenge and the main cause of death for the majority of cancer patients [1]. Thus attention has shifted toward a better understand- ing[r]

Molecular characterization of circulating tumor cells (CTC) is promising for personalized medicine. We aimed to identify a CTC gene expression profile predicting outcome to first-line aromatase inhibitors in metastatic breast cancer (MBC) patients.

Detection of circulating (CTC) or disseminated tumor cells (DTC) has been associated with negative prognosis and outcome in patients with colorectal cancer, though testing for these cells is not yet part of clinical routine. There are several different methodological approaches to detect tumor cells[r]

Recently, the prognostic significance of circulating tumor cells (CTCs) in primary breast cancer as assessed using the Food-and-Drug-Administration-approved CellSearch® system has been demonstrated.

Cytokines are involved in cancer invasion and metastasis. Circulating tumor cells (CTCs) play key role in tumor dissemination and are an independent survival predictor in breast cancer patients. The aim of this study was to assess correlation between CTCs and plasma cytokines in primary breast cance[r]

Discussion
To our knowledge, this is the first report of extremely high numbers of CTC in a case of squamous cell carcin- oma of oral cavity. At present, the CellSearch ® System is the most commonly used and the only Food and Drug Administration (FDA)-cleared CTC detection technique