BÁO CÁO Y HỌC: "MLN51 AND GM-CSF INVOLVEMENT IN THE PROLIFERATION OF FIBROBLAST-LIKE SYNOVIOCYTES IN THE PATHOGENESIS OF RHEUMATOID ARTHRITIS" PPS

patient samples suggests that mutations of hCDC4 do not play a significant role in the pathogenesis of AML. During sequence analysis of exon 10 in the AML samples we identified a new intronic SNP which we subsequently confirmed by sequencing DNA samples of 51 healthy individuals. Interestingl[r]

To address whether this polymorphism is associated with the risk for coronary heart disease and/or plasma lipid levels in women, we studied a group of 967 female patients with hyperlipid[r]

Despite a difficulty to identify mutations that render the resistance of BRCA cancer cells to PARP inhibition, there is evidence to suggest that PARP inhibitors may be useful in treating tumors in combination with cytotoxic drugs by increasing the sensitivity of the tumors to these agents. Indeed, i[r]

Quinn TC. Hepatitis C, hepatitis B, and human immunodeficiency virus infections among non-intravenous drug-using patients attending clinics for sexually transmitted diseases. J Infect Dis 1994; 169:990-995. 51. Goldberg D, McIntyre PG, Smith R, Appleyard K, Dunlop J, Taylor A, Hutchinson S. H[r]

Int. J. Med. Sci. 2006, 3 35International Journal of Medical Sciences ISSN 1449-1907 www.medsci.org 2006 3(2):35-40 ©2006 Ivyspring International Publisher. All rights reserved Review Hepatitis C Virus Serologic and Virologic Tests and Clinical Diagnosis of HCV-Related Liver Disease Stéphane Chevali[r]

Received: 2006.04.28; Accepted: 2006.05.25; Published: 2006.06.01 The original report published in 2001 on a possible association between maternal use of loratadine and an increased risk[r]

and severity of disease. Am J Gastroenterol 2001; 96:2957. 10. Pagano G, Pacini G, Musso G, et al. Nonalcoholic steatohepatitis, insulin resistance, and metabolic syndrome: Further evidence for an etiologic association. Hepatology 2002; 35:367. 11. Marchesini G, Brizi M, Morselli-Labate AM, et al. A[r]

HSGLT3 AND GLUT4 GENE EXPRESSION As shown in Figure 1, the median relative expression ratio 2-ΔΔCt of hSGLT3 transcript levels in skeletal muscle increased by a factor of 10.02 after 16 [r]

In addition, recently, it has been demonstrated that Cys-C is more sensitive for moderate renal dysfunction than Cr [7-9], that is, the patients with a 24 h-Cr clearance of 51-70 mL/min show a significant increase in the serum level of Cys-C, but no alteration of Cr was found for such patient[r]

A recombinant first-generation adenovirus ADrBMP6 was constructed and compared with ADhBMP6 in the process of bone formation_._ In the second set of experiments, human _BMP6_ cDNA was co[r]

In the second published pivotal trial of combined therapy with pegylated interferon and ribavirin, cirrhotic patients treated with peginterferon alfa-2a plus ribavirin for 48 weeks had S[r]

and basal core promoter mutations on viral replicative interference. Hepatology 2001;34:404-410. 41. Crespo J, Lozano JL, Carte B, de las Heras B, de la Cruz F, Pons-Romero F. Viral replication in patients with concomitant hepatitis B and C virus infections. Eur J Clin Microbiol Infect Dis 1997;16:4[r]

In the second published pivotal trial of combined therapy with pegylated interferon and ribavirin, cirrhotic patients treated with peginterferon alfa-2a plus ribavirin for 48 weeks had S[r]

We identified a sufficient number of epidemiologic studies on lung cancer to conduct a meta-analysis for genetic polymor-phisms in nucleotide excision repair pathway genes, focusing on x[r]

As in all positive-strand RNA viruses investigated thus far (reviewed in ref. [65]), HCV forms a membrane-associated replication complex, composed of viral proteins, replicating RNA, altered cellular membranes and additional host cell factors [50, 51]. A specific membrane alteration, referred[r]

16. Regelson W, Loria R, Kalimi M. Hormonal intervention: "buffer hormones" or "state dependency". The role of dehydroepian-drosterone (DHEA), thyroid hormone, estrogen and hypophy-sectomy in aging. Ann N Y Acad Sci. 1988; 521: 260-73. 17. Herbert J. Neurosteroids, brain damage, and mental illness.[r]

may cause adverse effects that need a discontinuous use, in about 20% of patients. [49] Oxipurinol inhibits xanthine oxidase too and is an alternative to allopuri-nol, but an allergy to allopurinol is a contraindication to its use, owing to cross-allergies between them. [50] Parental administration,[r]

cirrhosis.[51-53] Once decompensated cirrhosis occurs, the 5-year survival rate falls to 50%.[51] The time from HCV infection to cirrhosis is dependent on multiple factors, and cannot be predicted in an individual patient. Virtually all HCV-related HCC occurs among patients with cirrho[r]

INTRODUCTION Studies using the human hepatocellular carcinoma HCC cell line HepG2 have demonstrated a specific gene expression pattern induced by ethanol different from that observed in [r]

Treatment should be individualized in patients with the following characteristics: 1 acute HCV infection; 2 coinfection with HIV; 3 under 18 years of age; 4 chronic renal disease, on or [r]