CORRELATION BETWEEN IMMUNE-RELATED ADVERSE EVENTS AND PROGNOSIS IN PATIENTS WITH VARIOUS CANCERS TREATED WITH ANTI PD-1 ANTIBODY

Immune checkpoint blockade is developed as standard treatment for non-small cell lung cancer. However immune-related adverse events (irAE) have still unknown complications. Here, we report a patient with lung squamous cell carcinoma who developed neuromyelitis optica spectrum disorder with nivolumab[r]

asthma. Allergol Immunopathol 2001, 29(3):140-146.24. Wilkinson TM, Donaldson GC, Johnston SL, Openshaw PJ, WedzichaJA: Respiratory syncytial virus, airway inflammation, andFEV1 decline in patients with chronic obstructive pulmonarydisease. Am J Respir Crit Care Med 2006, 173(8)[r]

asthma. Allergol Immunopathol 2001, 29(3):140-146.24. Wilkinson TM, Donaldson GC, Johnston SL, Openshaw PJ, WedzichaJA: Respiratory syncytial virus, airway inflammation, andFEV1 decline in patients with chronic obstructive pulmonarydisease. Am J Respir Crit Care Med 2006, 173(8)[r]

Malnutrition in gastrectomized patients receiving chemotherapy is associated with the susceptibility to chemotherapy-related adverse events. This study evaluated pre-operative nutritional status-related indices associated with adverse events in post-operation gastric cancer patients receiving chemot[r]

Discussion
New biomarkers could be helpful in predicting treatment outcomes earlier and more precisely, which is of great interest to physicians and researchers in the field. This re- port describes for the first time that the proto-oncogene Bmi-1 is aberrantly e[r]

The pretreatment albumin to globulin ratio (AGR) has been reported to correlate with the long-term survival in patients with various cancers. However, there are no reports regarding the correlation between the pretreatment AGR and chemotherapeutic outcomes in patients with unresectable metastatic co[r]

Cancer patients undergo routine computed-tomography (CT) scans and, therefore, iodinated contrast media (ICM) administration. It is not known whether a time-dependent correlation exists between chemotherapy administration, contrast enhanced CT and onset of acute ICM-related adverse reactions (ARs).

To study the association between Apelin expression and the clinical features and postoperative prognosis in patients with gastric cancer (Int J Cancer 136:2388-2401, 2015). Methods: Tumor samples and matched adjacent normal tissues were collected from 270 patients with GC receiving surgical resectio[r]

Better methods to predict prognosis can play a supplementary role in administering individualized treatment for breast cancer patients. Altered expressions of PTHrP and TGF-β have been observed in various types of human cancers.

Obesity has been reported as an adverse prognostic factor in breast cancer, but inconsistently, and under-treatment with chemotherapy may occur. We provide the first assessment of obesity and breast cancer outcomes in a population-based, multi-ethnic cohort of New Zealand patients treated with chemo[r]

Chapter 097. Paraneoplastic Neurologic Syndromes (Part 2) Pathogenesis Most PNDs are mediated by immune responses triggered by neuronal proteins (onconeuronal antigens) expressed by tumors. In PNDs of the central nervous system (CNS), many antibody-associated immune resp[r]

To compare the prognosis of upper urinary tract (UUT)-urothelial carcinoma (UC) and UC of the bladder (UCB) by pathological staging in patients treated with radical surgeries. Methods: The study population comprised 335 and 302 consecutive radical surgery cases performed between 1991 and 2010 for UU[r]

Median age at diagnosis of patients with chronic lymphocytic leukemia (CLL) is > 70 years. However, the majority of clinical trials do not reflect the demographics of CLL patients treated in the community. We examined treatment patterns, outcomes, and disease-related mortality in patients ≥ 75 years[r]

This study aimed to identify the health-related quality of life (HRQOL) domains associated with prognosis by assessing longitudinal alterations in HRQOL in patients with advanced hepatocellular carcinoma receiving sorafenib.

Primary malignant melanoma of the vagina is extremely rare, with a poorer prognosis than cutaneous malignant melanoma. Previous studies have explored the repurposing of itraconazole, a common oral anti-fungal agent, for the treatment of various cancers.

To analyze the expression of karyopherin alpha 2 (KPNA2) in upper tract urothelial carcinoma (UTUC) and to investigate whether the KPNA2 expression provides additional prognostic information following radical nephroureterectomy (RNU).

Analysis of mutation and protein expression of EGFR in patients with lung adenocarcinoma. Investigation the hypermethylation frequency of EGFR, BRCA1, MGMT, MLH1, RASSF1A and correlation of the methylation between these genes with mutations and protein expression of EGFR.

Combined with the existing evidence, our data suggest that obtaining information on KIT mutations from pa- tients before the start of treatment would allow clinicians to predict who are most likely to experience resistance to primary imatinib therapy, to evaluate which patients would b[r]

etiology of thrombocytosis has not been established in most cases. Patients with thrombocytosis are nearly all asymptomatic. Thrombocytosis is not clearly linked to thrombosis in patients with cancer. Thrombocytosis is present in 40% of patients